Výsledky vyhledávání

Profiling of Caspase Signaling Pathways Predicts Clinical Response to Chemotherapy in Diffuse Large B-Cell Lymphomas

Autor: Hanneke C. Kluin-Nelemans, H van Krieken, Gert J. Ossenkoppele, Sagm Cillessen, Jjf Muris, [No Value] van Houdt, Cjlm Meijer, J. J. Oudejans, AJ Kummer

Publikováno v: Blood. 104:1544-1544

Disruption of the apoptosis signaling cascade is a probable cause for resistance to chemotherapy in patients with diffuse large B-cell lymphomas (DLBCL). We investigated whether inhibition of either or both caspase 8 and 9 apoptosis signaling pathway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9ba66102b90b0577445d92060d1ef00
https://doi.org/10.1182/blood.v104.11.1544.1544

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Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo

Autor: Eh, Spaeny-Dekking, Wl, Hanna, Am, Wolbink, Pc, Wever, Ja, Kummer, Aj, Kummer, Aj, Swaak, Jaap Michiel Middeldorp, Hg, Huisman, Cj, Froelich, Ce, Hack

Publikováno v: Europe PubMed Central

Activated CTLs and NK cells induce apoptosis via multiple mechanisms, including that termed granule exocytosis. The latter pathway consists of vectorial secretion of perforin and a family of granule-associated serine proteases (granzymes) to the targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8dec46a899ba93626c10771ea45d8da3
http://europepmc.org/abstract/med/9531325

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Akademický článek

Drug-induced apoptosis in lung cnacer cells is not mediated by the Fas/FasL (CD95/APO1) signaling pathway.

Autor: Ferreira CG; Division of Medical Oncology, University Hospital Vrije Universiteit Amsterdam, The Netherlands., Tolis C, Span SW, Peters GJ, van Lopik T, Kummer AJ, Pinedo HM, Giaccone G

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2000 Jan; Vol. 6 (1), pp. 203-12.

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Akademický článek

Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo.

Autor: Spaeny-Dekking EH; Central Laboratory of The Netherlands Red Cross Blood Transfusion Service, Amsterdam., Hanna WL, Wolbink AM, Wever PC, Kummer JA, Swaak AJ, Middeldorp JM, Huisman HG, Froelich CJ, Hack CE

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 1998 Apr 01; Vol. 160 (7), pp. 3610-6.

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Akademický článek

Nonfunctioning malignant paraganglioma of the posterior mediastinum with spinal cord compression. A case report.

Autor: Noorda RJ; Department of Orthopaedic Surgery, Academic Hospital, Free University, Amsterdam, The Netherlands., Wuisman PI, Kummer AJ, Winters HA, Rauwerda JA, Egeler-Peerdeman SM

Publikováno v: Spine [Spine (Phila Pa 1976)] 1996 Jul 15; Vol. 21 (14), pp. 1703-9.

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Akademický článek

Evidence that intestinal intraepithelial lymphocytes are activated cytotoxic T cells in celiac disease but not in giardiasis.

Autor: Oberhuber G; Department of Clinical Pathology, University of Vienna Medical School, Austria., Vogelsang H, Stolte M, Muthenthaler S, Kummer JA, Radaszkiewicz T

Publikováno v: The American journal of pathology [Am J Pathol] 1996 May; Vol. 148 (5), pp. 1351-7.

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Akademický článek

THE METABOLISM OF AMINO ACIDS AND CASEIN DIGEST IN PHLORHIZINIZED DOGS.

Autor: Hawkins WB; Department of Pathology, The University of Rochester School of Medicine and Dentistry, Rochester, New York., McKee FW, Hawley GM, Kummer AJ

Publikováno v: The Journal of experimental medicine [J Exp Med] 1947 Apr 30; Vol. 85 (5), pp. 479-89.

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