Zobrazeno 1 - 10
of 515
pro vyhledávání: '"AJ Green"'
Autor:
Frances A, Carter, M Joan, Taylor, Madeline J, Weston, Teresa A, Quigley, John H, Beveridge, Robert AJ, Green, Steve, Duffy, Joseph, Boden
Publikováno v:
The New Zealand medical journal. 131(1476)
To systematically assess the service satisfaction of consumers, their families and referrers with crisis resolution (CR).Consecutive consumers discharged after receiving CR over a five-week period were potentially eligible for participation, together
Autor:
Terri McVeigh, Duff M, Carroll C, O'Shea R, Bradley L, Farrell M, Dj, Gallagher, Clabby C, Aj, Green
Publikováno v:
Europe PubMed Central
MUTYH is involved in DNA damage repair. Bi-allelic MUTYH mutations predispose to polyposis and gastrointestinal malignancies, distinct genetically from autosomal dominant familial adenomatous polyposis coli. Two common European MUTYH mutations accoun
Autor:
Fairfoul G, Li, Mcguire, Pal S, James Ironside, Neumann J, Christie S, Joachim C, Esiri M, Sg, Evetts, Rolinski M, Baig F, Ruffmann C, Wade-Martins R, Mt, Hu, Parkkinen L, Aj, Green
Publikováno v:
Fairfoul, G, McGuire, L I, Pal, S, Ironside, J W, Neumann, J, Christie, S, Joachim, C, Esiri, M, Evetts, S G, Rolinski, M, Baig, F, Ruffmann, C, Wade-Martins, R, Hu, M T M, Parkkinen, L & Green, A J E 2016, ' Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies ', Annals of Clinical and Translational Neurology, vol. 3, no. 10, pp. 812-818 . https://doi.org/10.1002/acn3.338
Fairfoul, G, McGuire, L I, Pal, S, Ironside, J, Neumann, J, Christie, S, Joachim, C, Esiri, M, Evetts, S G, Rolinski, M, Baig, F, Ruffmann, C, Wade-Martins, R, Hu, M T M, Parkkinen, L & Green, A 2016, ' Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies ', Annals of Clinical and Translational Neurology . https://doi.org/10.1002/acn3.338
Europe PubMed Central
Fairfoul, G, McGuire, L I, Pal, S, Ironside, J, Neumann, J, Christie, S, Joachim, C, Esiri, M, Evetts, S G, Rolinski, M, Baig, F, Ruffmann, C, Wade-Martins, R, Hu, M T M, Parkkinen, L & Green, A 2016, ' Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies ', Annals of Clinical and Translational Neurology . https://doi.org/10.1002/acn3.338
Europe PubMed Central
We have developed a novel real-time quaking-induced conversion RT-QuIC-based assay to detect alpha-synuclein aggregation in brain and cerebrospinal fluid from dementia with Lewy bodies and Parkinson's disease patients. This assay can detect alpha-syn
Autor:
R Boden, AA Flynn, GM Boxer, Jason L. J. Dearling, J Bhatia, R. H. J. Begent, AJ Green, RB Pedley
Publikováno v:
International Journal of Radiation Biology. 77:507-517
To develop a model that relates the pattern of dose delivery during radio-immunotherapy to biological effect. This model was used to assess the efficacy of a range of antibodies labelled with 131I, 186Re and 90Y.Pharmacokinetic data were obtained by
Publikováno v:
Physics in Medicine and Biology. 44:N151-N159
Image registration is a powerful tool for correlating functional images with images of anatomical structure. This facilitates more accurate quantitation of regional radiopharmaceutical uptake. Similarly, registration of images of radiolabelled antibo
Autor:
KA Chester, N. Cushen, M.P. Napier, Robert E. Hawkins, Joanne L. Casey, Andrew J.W. Hilson, Richard H. J. Begent, CJ Johnson, L.D Hope‐Stone, M. J. Verhaar, Lisa Robson, AJ Green, P. A. Keep
Publikováno v:
Nature Medicine. 2:979-984
We present a system for cancer targeting based on single-chain Fv (scFv) antibodies selected from combinatorial libraries, produced in bacteria and purified by using an engineered tag. Combinatorial libraries of scFv genes contain great diversity, an
Autor:
DM Lane, KF Eagle, RHJ Begent, LD Hope-Stone, AJ Green, JL Casey, PA Keep, AMB Kelly, JA Ledermann, MG Glaser, AJW Hilson
Publikováno v:
British Journal of Cancer
Studies in animal tumour models of colorectal cancer suggest that F(ab')2 antibody fragments to carcinoembryonic antigen (CEA) labelled with iodine-131 give superior therapy compared with intact anti-CEA antibody. The purpose of this study was to inv
Autor:
Ethaar El-Emir, Jason L. J. Dearling, AJ Green, AA Flynn, R Boden, RB Pedley, GM Boxer, Ingrid A. Petrie, R. H. J. Begent
Publikováno v:
Physics in medicine and biology. 47(20)
Many agents using tumour-associated characteristics are deposited heterogeneously within tumour tissue. Consequently, tumour heterogeneity should be addressed when obtaining information on tumour biology or relating absorbed radiation dose to biologi
Autor:
P. A. Keep, KA Chester, Robert E. Hawkins, Richard H. J. Begent, Lisa Robson, AJ Green, RB Pedley, Greg Winter, GM Boxer, J.A. Boden LIBiol, O. Cochet
Publikováno v:
Lancet (London, England). 343(8895)
Insertion of antibody genes into filamentous bacteriophage makes it possible to generate and screen libraries of 10(7) or more antibodies. Each phage expresses an antibody on its surface and contains the corresponding antibody gene. Genes that encode