Zobrazeno 1 - 10
of 25
pro vyhledávání: '"AHR, Airway hyperresponsiveness"'
Autor:
Akio Niimi, Woo-Jung Song
Publikováno v:
The Journal of Allergy and Clinical Immunology. in Practice
Background Angiotensin converting enzyme inhibitor (ACEI) intolerance commonly occurs, requiring switching to an angiotensin-II receptor blocker (ARB). Angiotensin converting enzyme inhibitor intolerance may be mediated by bradykinin, potentially aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bb25a877d5efaa654b8965ed0e2944
https://pubmed.ncbi.nlm.nih.gov/33965593
https://pubmed.ncbi.nlm.nih.gov/33965593
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 6957-6962 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 6957-6962 (2021)
Graphical abstract
Asthma is a complicated lung disease, which has increased morbidity and mortality rates in worldwide. There is an overlap between asthma pathophysiology and mitochondrial dysfunction and MSCs may have regulatory effect on mito
Asthma is a complicated lung disease, which has increased morbidity and mortality rates in worldwide. There is an overlap between asthma pathophysiology and mitochondrial dysfunction and MSCs may have regulatory effect on mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d570e737062499ca4ded98c542acd9
https://pubmed.ncbi.nlm.nih.gov/34866995
https://pubmed.ncbi.nlm.nih.gov/34866995
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 8, Pp 4311-4317 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 8, Pp 4311-4317 (2021)
Graphical abstract
Asthma as chronic airway disease has high prevalence in children and imbalance of Th1/Th2 is a critical mechanism in pathogenesis of the asthma. Baicalein as a cell protective and anti-inflammatory flavonoid may have anti-asth
Asthma as chronic airway disease has high prevalence in children and imbalance of Th1/Th2 is a critical mechanism in pathogenesis of the asthma. Baicalein as a cell protective and anti-inflammatory flavonoid may have anti-asth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26865b6b27608bd63c98045b189ba319
https://doi.org/10.1016/j.sjbs.2021.04.009
https://doi.org/10.1016/j.sjbs.2021.04.009
Publikováno v:
Pharmacological Research
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b9b3d7b7767e97cb84ac3227c7da4
Autor:
Ji Hye Kim, Jung Won Park, Thomas S. Kupper, Jungsoo Lee, Ke Lun Zhang, Youdong Pan, Kyung Hee Park, Seo Hyeong Kim, Jongsun Lee, Ji Yeon Noh, HyeRan Kim, Chang Ook Park, Bomi Kim, Kyoung Yong Jeong, Kwang Hoon Lee, Howard Chu, Zheng-wang Sun
Publikováno v:
EBioMedicine, Vol 58, Iss, Pp 102879-(2020)
EBioMedicine
EBioMedicine
Background While the incidence of patients with atopic dermatitis (AD) with atopic march (AM) showing respiratory allergy is steadily rising, the pathomechanism is still unknown. There are currently no biomarkers to predict progression of AM. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09dac8f75a65d7395b7b64a1ba4bc1a
http://www.sciencedirect.com/science/article/pii/S2352396420302541
http://www.sciencedirect.com/science/article/pii/S2352396420302541
Autor:
Branchett, William J., Stölting, Helen, Oliver, Robert A., Walker, Simone A., Puttur, Franz, Gregory, Lisa G., Gabryšová, Leona, Wilson, Mark S., O'Garra, Anne, Lloyd, Clare M.
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Although originally defined as a type 2 (T2) immune-mediated condition, non-T2 cytokines, such as IFN-γ and IL-17A, have been implicated in asthma pathogenesis, particularly in patients with severe disease. IL-10 regulates TH cell phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0a7c940fb49fc00fa7f95debf0466019
https://pubmed.ncbi.nlm.nih.gov/31812572
https://pubmed.ncbi.nlm.nih.gov/31812572
Autor:
Sandisiwe Mangali, Martyna Scibiorek, Frank Kirstein, Amkele Ngomti, Jermaine Khumalo, Sabelo Hadebe, Frank Brombacher, Hlumani Ndlovu, Nontobeko Mthembu
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background B cells play an important role in allergies through secretion of IgE. IL-4 receptor α (IL-4Rα) is key in allergic asthma and regulates type 2 cytokine production, IgE secretion, and airway hyperresponsiveness. IL-4 activation of B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad3ec83f4328c2fc8eb949e8974ffd7
https://doi.org/10.1016/j.jaci.2020.12.635
https://doi.org/10.1016/j.jaci.2020.12.635
Autor:
Baranyi, Ulrike, Farkas, Andreas M., Hock, Karin, Mahr, Benedikt, Linhart, Birgit, Gattringer, Martina, Focke-Tejkl, Margit, Petersen, Arnd, Wrba, Fritz, Rülicke, Thomas, Valenta, Rudolf, Wekerle, Thomas
Publikováno v:
EBioMedicine
EBioMedicine, Vol 7, Iss C, Pp 230-239 (2016)
EBioMedicine, Vol 7, Iss C, Pp 230-239 (2016)
Background Therapeutic strategies for the prophylaxis of IgE-mediated allergy remain an unmet medical need. Cell therapy is an emerging approach with high potential for preventing and treating immunological diseases. We aimed to develop a cell-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1cff621a3dd57452f02889e4e632776e
http://europepmc.org/articles/PMC4909362
http://europepmc.org/articles/PMC4909362
Autor:
Aurora Vocale, Silvia Falco, Paola Rogliani, Luigino Calzetta, Beatrice Ludovica Ritondo, Francesco Facciolo
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss, Pp 100010-(2021)
Current Research in Pharmacology and Drug Discovery
Current Research in Pharmacology and Drug Discovery
Background Recurrent cow's milk (CM) aspiration is often associated with gastroesophageal reflux in infants and toddlers and it seems to be implicated in the etiology of different inflammatory lung disorders. This study aimed to investigate ex vivo t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182b2ebd60c3558e8e128d46e5200c67
https://doi.org/10.1016/j.crphar.2020.100010
https://doi.org/10.1016/j.crphar.2020.100010
Autor:
Onn Min Kon, Alberto Papi, Luminita A. Stanciu, Jie Zhu, Christine K. Ward, Marco Contoli, Simon D. Message, Mary Ann Mascelli, Michael R. Edwards, Peter K. Jeffery, Elliot S. Barnathan, Tatiana Kebadze, Sebastian L. Johnston, Patrick Mallia
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background The innate immune system senses viral infection through pattern recognition receptors (PRRs), leading to type I interferon production. The role of type I interferon and PPRs in rhinovirus-induced asthma exacerbations in vivo are uncertain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b155e0565de09a673f8091ddc072c443
http://hdl.handle.net/11392/2397435
http://hdl.handle.net/11392/2397435
