Zobrazeno 1 - 10
of 7 016
pro vyhledávání: '"AHR"'
Autor:
Sarah E. Morgan, Lisa A. DeLouise
Publikováno v:
Eco-Environment & Health, Vol 3, Iss 3, Pp 347-354 (2024)
This project reports on the use of a novel nanomembrane filtering technology to isolate and analyze the bioactivity of microplastic (MP)-containing debris from Lake Ontario water samples. Environmental MPs are a complex mixture of polymers and sorbed
Externí odkaz:
https://doaj.org/article/416d4b64bc5c49cb8e4931134b8621f3
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant that disrupts hepatic function leading to steatotic liver disease (SLD)-like pathologies, such as steatosis, steatohepatitis, and fibrosis. These effects ar
Externí odkaz:
https://doaj.org/article/fb48d6e31421443c87289a33eda499ff
Autor:
Takeshi Yasuda, Tomohisa Takagi, Kohei Asaeda, Hikaru Hashimoto, Mariko Kajiwara, Yuka Azuma, Hiroaki Kitae, Yasuko Hirai, Katsura Mizushima, Toshifumi Doi, Ken Inoue, Osamu Dohi, Naohisa Yoshida, Kazuhiko Uchiyama, Takeshi Ishikawa, Hideyuki Konishi, Yuichi Ukawa, Akiko Kohara, Masatake Kudoh, Ryo Inoue, Yuji Naito, Yoshito Itoh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Maintaining the mucus layer is crucial for the innate immune system. Urolithin A (Uro A) is a gut microbiota-derived metabolite; however, its effect on mucin production as a physical barrier remains unclear. This study aimed to elucidate the
Externí odkaz:
https://doaj.org/article/52427b2d7a264fa0b2fe3c9fb621bc4e
Autor:
Arnaud Jacquerie, Ann Hoeben, Daniëlle B. P. Eekers, Alida A. Postma, Maxime Vanmechelen, Frederik de Smet, Linda Ackermans, Monique Anten, Kim Severens, Axel zur Hausen, Martinus P. G. Broen, Jan Beckervordersandforth
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Glioblastoma (GBM) continues to exhibit a discouraging survival rate despite extensive research into new treatments. One factor contributing to its poor prognosis is the tumor's immunosuppressive microenvironment, in which the kynurenine pat
Externí odkaz:
https://doaj.org/article/0c333146661840be874a5e7bc5fc17a2
Autor:
Mina Rahmati, Mojtaba Zare Ebrahimabad, Alale Langari, Ali Najafi, Shohreh Taziki, Alireza Norouzi, Mehrdad Teimoorian, Milad Khorasani, Saeed Mohammadi
Publikováno v:
Immuno, Vol 4, Iss 2, Pp 159-171 (2024)
Chronic hepatitis B (CHB) poses treatment challenges, with treatment response and disease outcome often determined by the immune response, particularly mononuclear phagocytes. Monocytes can differentiate into various subpopulations influenced by AHR.
Externí odkaz:
https://doaj.org/article/9347c79f21a94382972da35e101d24cd
Autor:
Manxiu Huai, Yingjie Wang, Junhao Li, Jiaxing Pan, Fang Sun, Feiyu Zhang, Yi Zhang, Leiming Xu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Imperceptible examination and unideal treatment effect are still intractable difficulties for the clinical treatment of pancreatic ductal adenocarcinoma (PDAC). At present, despite 5-fluorouracil (5-FU), as a clinical first-line FOLFIRINOX c
Externí odkaz:
https://doaj.org/article/4cfd0131ed7f45a695d4fe096f464496
Autor:
Hang Yu, Jingmin Fan, Rui Xue, Jiawei Guan, Fangyuan Tian, Yu Xu, Linyun He, Ji Liu, Zhenzhu Du, Daqun Chen, Wei Yu, Wen Chen, Bo Han
Publikováno v:
Food Frontiers, Vol 5, Iss 3, Pp 1320-1337 (2024)
Abstract Alhagi honey (AH) is produced in arid and hot areas of Central Asia, and its polysaccharides (AP) are widely known for their activity in the treatment of intestinal diseases such as diarrhea. However, the therapeutic potential and mechanism
Externí odkaz:
https://doaj.org/article/c30d72b6be3348bca67e94703d073bb4
Autor:
Natalija Jonić, Ivan Koprivica, Stavroula G. Kyrkou, Vasileios-Panagiotis Bistas, Christos Chatzigiannis, Nataša Radulović, Ivan Pilipović, Andjelina Jovanović, Milan B. Jovanović, Mirjana Dimitrijević, Andreas G. Tzakos, Ivana Stojanović
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type 1 diabetes (T1D) is an autoimmune disease with a strong chronic inflammatory component. One possible strategy for the treatment of T1D is to stimulate the regulatory arm of the immune response, i.e. to promote the function of tolerogenic dendrit
Externí odkaz:
https://doaj.org/article/11b51184e3184bd1b78ab93ef5a4d033
Autor:
Shenghui Liu
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37265- (2024)
The aryl hydrocarbon receptor (AHR) is a transcription factor activated by ligands that participates in many important physiological processes. Although AHR activation is associated with hepatomegaly, the underlying mechanism remains unclear. This st
Externí odkaz:
https://doaj.org/article/62373f59631d44a3a0146034b14d1358
Autor:
Fatemah Bahman, Khubaib Choudhry, Fatema Al-Rashed, Fahd Al-Mulla, Sardar Sindhu, Rasheed Ahmad
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The aryl hydrocarbon receptor (AhR) is a versatile environmental sensor and transcription factor found throughout the body, responding to a wide range of small molecules originating from the environment, our diets, host microbiomes, and internal meta
Externí odkaz:
https://doaj.org/article/4e0144c1dbbb494c8b09a0a96856fe6e