Výsledky vyhledávání - "AE von dem Borne"

Detection of human monocyte-reactive alloantibodies by flow cytometry after selective downmodulation of the Fc receptor I

Autor: RW Kuijpers, MC Dooren, AE von dem Borne, WH Ouwehand

Publikováno v: Blood. 78:2150-2156

Monocyte-reactive human alloantibodies may be of importance in situations such as transfusion reactions and bone marrow and kidney transplantation. So far, only complement-binding monocyte-reactive antibodies can be detected with a cytotoxicity assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95918d73d8713e69863ee86ddc1d23ae
https://doi.org/10.1182/blood.v78.8.2150.bloodjournal7882150

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Deficiency of glycosyl-phosphatidylinositol-linked membrane glycoproteins of leukocytes in paroxysmal nocturnal hemoglobinuria, description of a new diagnostic cytofluorometric assay

Autor: CE van der Schoot, TW Huizinga, ET van 't Veer-Korthof, R Wijmans, J Pinkster, AE von dem Borne

Publikováno v: Blood. 76:1853-1859

Paroxysmal nocturnal hemoglobinuria (PNH) is a disease that affects not only red cells, but other blood cells as well. The common defect is supposed to be an acquired deficiency of glycosyl-phosphatidylinositol (GPI)-anchored membrane proteins, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c291e7465df70b39579a45eaed9d97d4
https://doi.org/10.1182/blood.v76.9.1853.bloodjournal7691853

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Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells

Autor: JM Kerst, M de Haas, CE van der Schoot, IC Slaper-Cortenbach, M Kleijer, AE von dem Borne, RH van Oers

Publikováno v: Blood. 82(11)

We performed a detailed kinetic study on the in vivo effect of a single subcutaneous dose of granulocyte colony-stimulating factor (G-CSF; 300 micrograms) in four healthy individuals on the expression and function of neutrophil Fc gamma receptors (Fc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c551fd2894003e6566b8edd86a81ddf
https://pubmed.ncbi.nlm.nih.gov/7694676

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Expression and release of CD27 in human B-cell malignancies

Autor: MH van Oers, ST Pals, LM Evers, CE van der Schoot, G Koopman, JM Bonfrer, RQ Hintzen, AE von dem Borne, RA van Lier

Publikováno v: Blood. 82(11)

CD27, a transmembrane disulfide-linked 55-kD homodimer, belongs to the nerve growth factor-receptor family, a group of homologous molecules involved in lymphocyte differentiation and selection. It is expressed on mature thymocytes, peripheral blood T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eeaa9e0cc60e4ea36eeab5f705a01ce
https://pubmed.ncbi.nlm.nih.gov/8241510

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Glanzmann's thrombasthenia caused by homozygosity for a splice defect that leads to deletion of the first coding exon of the glycoprotein IIIa mRNA

Autor: S Simsek, H Heyboer, LG de Bruijne-Admiraal, R Goldschmeding, HT Cuijpers, AE von dem Borne

Publikováno v: Blood. 81(8)

Glanzmann's thrombasthenia (GT) is the result of the absence or of an altered and dysfunctional expression on the platelet membrane of the fibrinogen receptor (glycoprotein [GP] IIb/IIIa complex). Various molecular genetic mechanisms have been found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e75a6e7bc21c8519fd45f3c7fd76ce
https://pubmed.ncbi.nlm.nih.gov/8471765

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Granulocyte colony-stimulating factor induces hFc gamma RI (CD64 antigen)-positive neutrophils via an effect on myeloid precursor cells

Autor: JM Kerst, JG van de Winkel, AH Evans, M de Haas, IC Slaper-Cortenbach, TP de Wit, AE von dem Borne, CE van der Schoot, RH van Oers

Publikováno v: Blood. 81(6)

In this study we have examined hFc gamma RI expression during myelopoiesis. Normal bone marrow (BM) cells were found to express hFc gamma RI up to the metamyelocyte stage. A different Fc gamma RI expression pattern was observed in an in vitro model o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe3ddb93253f48e61c031835c207bc4
https://pubmed.ncbi.nlm.nih.gov/7680917

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Alpha 4 beta 1 and alpha 5 beta 1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way

Autor: JM Kerst, JB Sanders, IC Slaper-Cortenbach, MC Doorakkers, B Hooibrink, RH van Oers, AE von dem Borne, CE van der Schoot

Publikováno v: Blood. 81(2)

To study the receptors involved in the interaction between extracellular matrix proteins and hematopoietic progenitor cells, we analyzed the expression of beta 1 integrins on CD34+ bone marrow cells by means of immunoflowcytometry. Alpha 4 beta 1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3426f0b8e1a00c95b407a11b97bffb03
https://pubmed.ncbi.nlm.nih.gov/7678511

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Single point mutation in human glycoprotein IIIa is associated with a new platelet-specific alloantigen (Mo) involved in neonatal alloimmune thrombocytopenia

Autor: RW Kuijpers, S Simsek, NM Faber, R Goldschmeding, RK van Wermerkerken, AE von dem Borne

Publikováno v: Blood. 81(1)

Here we describe a new platelet-specific alloantigen that was identified in a case of neonatal alloimmune thrombocytopenia. This antigen has provisionally been called “Mo.” By studying the Mo family, it was shown to be inherited in an autosomal d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67193f45232e548afd8c33dc37fff1c4
https://pubmed.ncbi.nlm.nih.gov/8093349

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Localization of the platelet-specific HPA-2 (Ko) alloantigens on the N-terminal globular fragment of platelet glycoprotein Ib alpha

Autor: RW Kuijpers, WH Ouwehand, PM Bleeker, D Christie, AE von dem Borne

Publikováno v: Blood. 79(1)

The human platelet-specific alloantigens HPA-2a and HPA-2b (= Kob and Koa) together constitute a biallelic antigen system. The HPA-2 antigens have not, to date, been located on a particular platelet membrane molecule. Here, we describe the localizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1534d11fb9cff6cc4a0974c157ca08d6
https://pubmed.ncbi.nlm.nih.gov/1370207

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