Zobrazeno 1 - 10
of 12 360
pro vyhledávání: '"ADRIAMYCIN"'
Autor:
Jialu Weng, Shiyi Wu, Yating Pan, Yifan Lai, Jinrong Zhu, Wenzhang Jin, Deyu Lu, Yizhang Chen, Zhijie Yu, Xinjie Zan, Jinglin Xia
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101311- (2024)
Chemotherapy is the primary palliative treatment for advanced hepatocellular carcinoma (HCC). However, the systemic delivery is associated with the drawbacks including a high risk of adverse effects and a low efficacy. Therefore, local injection ther
Externí odkaz:
https://doaj.org/article/77372ebd5ad94134bbf3281b67351d12
Publikováno v:
Organogenesis, Vol 20, Iss 1 (2024)
ABSTRACTThis study is to investigate the therapeutical effect and mechanisms of human-derived adipose mesenchymal stem cells (ADSC) in relieving adriamycin (ADR)-induced nephropathy (AN). SD rats were separated into normal group, ADR group, ADR+Losar
Externí odkaz:
https://doaj.org/article/6f6107a8d5a24e7cae1b5fd354600090
Autor:
Yue Liu, Xiao-ya Zhu, Li-li Liao, Zhan-hui Zhang, Tao-sheng Huang, Ling Zhang, Xi-wen Jiang, Yi Ma
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Most patients with acute myeloid leukemia (AML) eventually develop drug resistance, leading to a poor prognosis. Dysregulated long gene non coding RNAs (lincRNAs) have been implicated in chemoresistance in AML. Unfortunately, the
Externí odkaz:
https://doaj.org/article/7e415f1e88de446e99462b39ab2b8281
Autor:
Astri Astuti, I Gede Sumantra, Adila Aafiyah, R. Maman Abdurahman, Teddy Arnold Sihite, Mohammad Rizki Akbar, Melawati Hasan, Erwan Martanto
Publikováno v:
International Journal of Integrated Health Sciences, Vol 12, Iss 1, Pp 55-64 (2024)
Objective: To assess the cardioprotective effects of Carvedilol in preventing subclinical left ventricular dysfunction (SLVD) in breast cancer patients after completing FAC chemotherapy. Methods: This prospective study employed a quasi-experimental
Externí odkaz:
https://doaj.org/article/e4c44564203f4b01ab9e9668ccff7521
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 2, Pp 233-240 (2024)
Objective(s): Due to its negative side effects, mainly nephrotoxicity, adriamycin (ADR) is used fairly infrequently. The purpose of this study is to investigate the effects of N-acetyl cysteine (NAC) on the immunoreactivity of spexin (SPX) in the kid
Externí odkaz:
https://doaj.org/article/2a57a11d48bb4f2a944d6bc5e1858ad4
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 81-90 (2024)
Introduction: Sodium-glucose cotransporter 2 (SGLT2) inhibitors target SGLT2 in renal proximal tubules and promote glycosuria in type 2 diabetes mellitus in humans and animal models, resulting in reduced blood glucose levels. Although clinical trials
Externí odkaz:
https://doaj.org/article/0c74f7d139b74404a08bd234905a2bfc
Publikováno v:
Ain Shams Engineering Journal, Vol 15, Iss 6, Pp 102721- (2024)
Anthracyclines exert cytotoxic effects on cancer cells through genotoxicity, inducing damage to their genetic material and impeding their reproductive capacity. The compound possesses a molecular framework consisting of an anthracycline ring system,
Externí odkaz:
https://doaj.org/article/94d2cdae7e434564bb185b283f821d6e
Autor:
Shuai Wang, Hefeng Geng, Yizhen Li, Ziang Xu, Kaisi Yang, Ling Yang, Fuhai Hui, Yingshi Zhang
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30759- (2024)
Background: Transarterial chemoembolization (TACE) is a common treatment for hepatocellular carcinoma (HCC), but the best therapeutic agent for TACE treatment has not been determined. The neutrophil/lymphocyte ratio (NLR) is a systemic immune system
Externí odkaz:
https://doaj.org/article/b84f52235c0d44d991ace1eb8eeba335
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 12, Pp 1814-1821 (2023)
Objective To investigate the effects of adipocyte plasma membrane-associated protein (APMAP) over-expression on glomerular podocyte injury in adriamycin (ADR) nephropathy. Methods The rat model of adriamycin nephropathy was constructed by tail vein i
Externí odkaz:
https://doaj.org/article/3220590f95ec46c295b3b35abc31fa1a
Publikováno v:
Zhongguo shipin weisheng zazhi, Vol 35, Iss 10, Pp 1416-1423 (2023)
ObjectiveThe aim of this study was to explore the protective effect of kaempferol against adriamycin-induced renal injury in rats and its underlying mechanism.MethodsA rat model of renal injury was established by adriamycin injection. The rats were d
Externí odkaz:
https://doaj.org/article/3f550f3a930d40329c55dc6f92db2492