Zobrazeno 1 - 10 of 68 pro vyhledávání: '"ADR, adverse drug reaction"'
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Akademický článek
The cholesterol-lowering effect of statins is modified by LILRB5 intolerance genotype: Results from a recruit-by-genotype clinical trial
Autor: Aleksi Tornio, Margherita Bigossi, Moneeza K. Siddiqui, Gwen Kennedy, Ala’a Melhem, Mehul K. Chourasia, Cyrielle Maroteau, Roberto Pola, Daniel I. Chasman, Alexander S. F. Doney, Colin N. A. Palmer
Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)
Background/Aims: Statin intolerance leads to poor adherence to statin therapy, resulting in a failure to achieve desired cholesterol reduction and adverse outcomes. The LILRB5 Asp247Gly genotype has been identified as being associated with statin int
Externí odkaz: https://doaj.org/article/0d4d6d2d4d054897bf926eddaa49e459
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2
A review on machine learning approaches and trends in drug discovery
Autor: Victor Maojo, Nereida Rodriguez-Fernandez, Adrian Carballal, Carlos Fernandez-Lozano, Francisco J. Novoa, Alejandro Pazos, Paula Carracedo-Reboredo, Francisco Cedrón, Jose Liñares-Blanco
Publikováno v: Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4538-4558 (2021)
RUC. Repositorio da Universidade da Coruña
instname
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • Machine Learning in drug discovery has greatly benefited the pharmaceutical industry. • Application of machine algorithms must entail a robust design in real clinical tasks. • Trending machine learning algor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1455b1a18d7c6c8d727e34d6b7d78f8
http://www.sciencedirect.com/science/article/pii/S2001037021003421
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3
Akademický článek
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4
Receptor-mediated targeted drug delivery systems for treatment of inflammatory bowel disease: Opportunities and emerging strategies
Autor: Caifang Gao, Peng Liu, Hongguo Chen, Xu Wu, Xudong Tang, Yitao Wang, Chi Teng Vong, Shengpeng Wang
Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)
Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical manifestations and high risks of cancerization. With no curative therapy for IBD at present, the development of effective therapeutics is highly advocated. Drug de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf33f667c4f81b143c5ccef5cfb99fc
http://europepmc.org/articles/PMC8463263
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6
Prevalence and real-world assessment of central aortic blood pressure in adult patients with essential hypertension uncontrolled on single anti-hypertensive agents
Autor: Ranjan Kumar Sharma, Ravi M. Tiwari, Abhay Joshi, Manish Verma, Chirag Trivedi, Deepa Chodankar
Publikováno v: Indian Heart Journal
Indian Heart Journal, Vol 70, Iss, Pp S213-S220 (2018)
Objective: To assess the prevalence of high central aortic pressure (CAP) in Indian patients with uncontrolled essential hypertension while on anti-hypertensive monotherapy. Also, to determine correlation between brachial blood pressure (BBP) and CAP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e877125d1d18453352f37870601fac0
http://europepmc.org/articles/PMC6310176
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7
French organization for the pharmacovigilance of COVID-19 vaccines: A major challenge
Autor: Francesco Salvo, Aurélie Grandvuillemin, Annie-Pierre Jonville-Béra, Sophie Gautier, Nathalie Massy, Marie-Blanche Valnet-Rabier, Valérie Gras-Champel, Céline Mounier, Clémence Lacroix, Antoine Pariente, Joëlle Micallef, Mehdi Benkebil
Publikováno v: Thérapie
Thérapie, EDP Sciences-Depuis 2016, la revue Thérapie n’est plus publiée par EDP Sciences.> Therapies (Elsevier), 2021, 76 (4), pp.297-303. ⟨10.1016/j.therap.2021.05.003⟩
Therapie
International audience; In this special issue, we present the main highlights of the first weeks of pharmacovigilance monitoring of coronavirus disease 2019 (COVID-19) vaccines in this unprecedented situation in France: the deployment of a vaccinatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a9398537631f6cf579fe428909c272
https://pubmed.ncbi.nlm.nih.gov/34059351
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8
Safety and efficacy of lopinavir/ritonavir combination in COVID-19: A systematic review, meta-analysis, and meta-regression analysis
Autor: Anusuya, Bhattacharyya, Subodh, Kumar, Phulen, Sarma, Hardeep, Kaur, Manisha, Prajapat, Nishant, Shekhar, Seema, Bansal, Pramod, Avti, Mythili, Hazarika, Saurabh, Sharma, Dhruv, Mahendru, Ajay, Prakash, Bikash, Medhi
Publikováno v: Indian Journal of Pharmacology
BACKGROUND: Being protease inhibitors and owing to their efficacy in SARS-CoV, lopinavir + ritonavir (L/R) combination is being used in the management of COVID-19. In this systematic review and meta-analysis, we have evaluated the comparative safety
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c0e4969b0fb1c6bb8cf64362cbf259e
https://pubmed.ncbi.nlm.nih.gov/33078733
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9
Clinical characteristics and management of iodine contrast media-related anaphylactic shock during cardiac catheterization
Autor: Hongliang Zhang, Fenghuan Hu, Yong Wang, Zhiwei Huang, Shubin Qiao, Weixian Yang
Publikováno v: The World Allergy Organization Journal
World Allergy Organization Journal, Vol 13, Iss 9, Pp 100459-(2020)
Objective This study aimed to investigate the clinical characteristics and impact of intra-aortic balloon pump (IABP) implantation on the prognosis of patients with anaphylactic shock (AS) during cardiac catheterization. Methods We analyzed the medic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c68a3871ec349536f774ec50f06ca37
http://europepmc.org/articles/PMC7486688
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