Rosiglitazone-induced white adipocyte browning is regulated by actin and Myh9.

Autor: Chen L; Key Laboratory of Agriculture Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China., Hao J; Key Laboratory of Agriculture Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China., Zhang J; Key Laboratory of Agriculture Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China., Wu J; Key Laboratory of Agriculture Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China., Ren Z; Key Laboratory of Agriculture Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China; Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan, Hubei 430070, China; Hubei Hongshan Laboratory, Wuhan, Hubei 430070, China. Electronic address: renzq@mail.hzau.edu.cn.

Publikováno v: Life sciences [Life Sci] 2024 Dec 15; Vol. 359, pp. 123217. Date of Electronic Publication: 2024 Nov 05.

cAMP driven UCP1 induction in human adipocytes requires ATGL-catalyzed lipolysis.

Autor: Desai A; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA., Loureiro ZY; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA; Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA., DeSouza T; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA., Yang Q; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA; Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA., Solivan-Rivera J; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA; Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA., Corvera S; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA; Diabetes Center of Excellence, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA; Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA. Electronic address: silvia.corvera@umassmed.edu.

Publikováno v: Molecular metabolism [Mol Metab] 2024 Dec; Vol. 90, pp. 102051. Date of Electronic Publication: 2024 Oct 23.

Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes.

Autor: Wang T; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Sharma AK; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Wu C; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Maushart CI; Department of Endocrinology, Diabetes, and Metabolism, University Hospital of Basel and University of Basel, Basel, Switzerland., Ghosh A; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Yang W; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Stefanicka P; Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine and University Hospital, Comenius University in Bratislava, Bratislava, Slovakia., Kovanicova Z; Institute of Experimental Endocrinology, Biomedical Research Center at the Slovak Academy of Sciences, Bratislava, Slovakia., Ukropec J; Institute of Experimental Endocrinology, Biomedical Research Center at the Slovak Academy of Sciences, Bratislava, Slovakia., Zhang J; Laboratory of Exercise and Health, Health Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Schwerzenbach, Switzerland., Arnold M; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Klug M; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., De Bock K; Laboratory of Exercise and Health, Health Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Schwerzenbach, Switzerland., Schneider U; Department of Surgery, Cantonal Hospital of Baden, Im Ergel 1, 5404 Baden, Switzerland., Popescu C; Department of Nuclear Medicine, Cantonal Hospital of Baden, Im Ergel 1, 5404 Baden, Switzerland., Zheng B; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China., Ding L; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Long F; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Dewal RS; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Moser C; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Sun W; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Dong H; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland., Takes M; Department of Radiology and Nuclear Medicine, University Hospital of Basel, Basel, Switzerland., Suelberg D; Department of Surgery, Cantonal Hospital of Baden, Im Ergel 1, 5404 Baden, Switzerland., Mameghani A; Department of Surgery, Cantonal Hospital of Baden, Im Ergel 1, 5404 Baden, Switzerland., Nocito A; Department of Surgery, Cantonal Hospital of Baden, Im Ergel 1, 5404 Baden, Switzerland., Zech CJ; Department of Radiology and Nuclear Medicine, University Hospital of Basel, Basel, Switzerland., Chirindel A; Department of Radiology and Nuclear Medicine, University Hospital of Basel, Basel, Switzerland., Wild D; Department of Radiology and Nuclear Medicine, University Hospital of Basel, Basel, Switzerland., Burger IA; Department of Nuclear Medicine, Cantonal Hospital of Baden, Im Ergel 1, 5404 Baden, Switzerland; Department of Nuclear Medicine, University Hospital of Zurich, University of Zurich, Zurich, Switzerland., Schön MR; Städtisches Klinikum Karlsruhe, Clinic of Visceral Surgery, Karlsruhe, Germany., Dietrich A; Clinic for Visceral, Transplant and Thoracic and Vascular Surgery, University Hospital Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany., Gao M; Department of Pharmacy, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China., Heine M; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany., Sun Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Vargas-Castillo A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Søberg S; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark; The Center of Inflammation and Metabolism and the Center for Physical Activity Research, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark., Scheele C; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark; The Center of Inflammation and Metabolism and the Center for Physical Activity Research, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark., Balaz M; Institute of Experimental Endocrinology, Biomedical Research Center at the Slovak Academy of Sciences, Bratislava, Slovakia; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia., Blüher M; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Germany & Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital, Leipzig, Germany. Electronic address: matthias.blueher@medizin.uni-leipzig.de., Betz MJ; Department of Endocrinology, Diabetes, and Metabolism, University Hospital of Basel and University of Basel, Basel, Switzerland. Electronic address: matthias.betz@usb.ch., Spiegelman BM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Wolfrum C; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology ETH Zurich, Schwerzenbach, Switzerland. Electronic address: christian-wolfrum@ethz.ch.

Publikováno v: Cell metabolism [Cell Metab] 2024 Sep 03; Vol. 36 (9), pp. 2130-2145.e7. Date of Electronic Publication: 2024 Jul 30.

NDUFA9 and its crotonylation modification promote browning of white adipocytes by activating mitochondrial function in mice.

Autor: Liu Y; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Liu Z; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Ren Z; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Han Q; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Chen X; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Han J; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Qiu G; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China., Sun C; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: sunchao2775@163.com.

Publikováno v: The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2024 Jun; Vol. 171, pp. 106583. Date of Electronic Publication: 2024 Apr 22.

BDE-99 stimulates generation of aberrant brown/beige adipocytes.

Autor: Wen Q; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100190, China; Beijing Institute of Basic Medical Sciences, Beijing, 100850, China., Xie X; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100190, China. Electronic address: xnxie@rcees.ac.cn., Ren Q; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100190, China., Pan R; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100190, China., Du Y; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100190, China.

Publikováno v: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2024 Apr 15; Vol. 347, pp. 123761. Date of Electronic Publication: 2024 Mar 09.