Zobrazeno 1 - 10
of 1 255
pro vyhledávání: '"ADH1B"'
Autor:
Alexander Jordan, BSc, Charlotte Näslund-Koch, MD, Signe Vedel-Krogh, PhD, Stig Egil Bojesen, DMSc, Lone Skov, DMSc
Publikováno v:
JAAD International, Vol 15, Iss , Pp 197-205 (2024)
Background: Psoriasis is associated with high alcohol consumption, but the causality of this relationship is unclear. Objective: We aimed to use a Mendelian randomization approach to investigate the causal effects of alcohol on incident psoriasis. Me
Externí odkaz:
https://doaj.org/article/be48f4c253684970a37e13a3243e816d
Autor:
Yukiko Owaki, Hisashi Yoshimoto, Go Saito, Shohei Dobashi, Satoshi Kushio, Akihiro Nakamura, Takahiro Goto, Yusuke Togo, Kazumasa Mori, Hideki Hokazono
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background It is unclear whether brief interventions using the combined classification of alcohol-metabolizing enzymes aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) together with behavioral changes in alcohol use can
Externí odkaz:
https://doaj.org/article/0ff9d60c14c94b97a5013ee41e19e759
Autor:
Min H Chuah, Megan P Leask, Ruth K Topless, Gregory D Gamble, Nicholas A Sumpter, Lisa K Stamp, Tony R Merriman, Nicola Dalbeth
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Alcohol consumption is a risk factor for hyperuricaemia and gout. Multiple single-nucleotide polymorphisms (SNPs) have been identified as associated with both alcohol consumption and serum urate or gout in separate genome-wide ass
Externí odkaz:
https://doaj.org/article/18374dbc3e0b4c9eab56923d21d4cba1
Autor:
Biao Zhang, Yu‐Hui Peng, Yun Luo, Chao‐Qun Hong, Yi‐Wei Lin, Yu‐Ling Zhang, Yi‐Wei Xu, Xue‐Fen Su, Fang‐Cai Wu
Publikováno v:
Cancer Medicine, Vol 12, Iss 20, Pp 20437-20449 (2023)
Abstract Background Previous studies have shown that ALDH2 and ADH1B genes may be associated with alcohol metabolism and the risk of esophageal squamous cell carcinoma (ESCC), with inconsistent results. This meta‐analysis aimed at comprehensively a
Externí odkaz:
https://doaj.org/article/a176eb8c19924e3bb5f9cbe85226d004
Autor:
Yoonsu Cho, Kuang Lin, Su-Hyun Lee, Canqing Yu, Dan Schmidt Valle, Daniel Avery, Jun Lv, Keumji Jung, Liming Li, George Davey Smith, China Kadoorie Biobank Collaborative Group, Dianjianyi Sun, Zhengming Chen, Iona Y. Millwood, Gibran Hemani, Robin G. Walters
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Although it is known that variation in the aldehyde dehydrogenase 2 (ALDH2) gene family influences the East Asian alcohol flushing response, knowledge about other genetic variants that affect flushing symptoms is limited. Methods
Externí odkaz:
https://doaj.org/article/98e9e7d2e7b64263ace2543576b8a573
Akademický článek
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Akademický článek
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Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 747-759 (2023)
Abstract Background ADH1B rs1229984 and ALDH2 rs671 are the specifically prevalent functional variants in the East Asians. These variants, which result in a dramatic change in enzyme activity, are highly associated with alcohol‐related disorders an
Externí odkaz:
https://doaj.org/article/5ac352888c5b4534924679a34e7e4ada
Autor:
Xiaoxiao Jiang, Chunlong Yan, Hanlin Zhang, Li Chen, Rui Jiang, Kexin Zheng, Wanzhu Jin, Huijuan Ma, Xiaomeng Liu, Meng Dong
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Alcohol is an essential drug in human life with multiple medical functions, but excessive alcohol intake, even a single episode of binge drinking, can cause serious damage. Reducing alcohol consumption or absorption is a direct way to allevi
Externí odkaz:
https://doaj.org/article/4d0ed03129a9446ca8eb87a7775c5913
Autor:
Yukiko Owaki, Hisashi Yoshimoto, Go Saito, Takahiro Goto, Satoshi Kushio, Akihiro Nakamura, Yusuke Togo, Kazumasa Mori, Hideki Hokazono
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background The alcohol-metabolizing enzyme aldehyde dehydrogenase 2 (ALDH2) is a carcinogenic acetaldehyde-degrading enzyme, and its low activity is a genetic constitution peculiar to East Asians. People with low alcohol dehydrogenase 1B act
Externí odkaz:
https://doaj.org/article/024a67772a414905bda2f2d71a397ee8