Zobrazeno 1 - 10
of 27
pro vyhledávání: '"ADAM17 (a disintegrin and metalloprotease 17)"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Wagdi Almishri, Liam A. Swain, Charlotte D’Mello, Tyson S. Le, Stefan J. Urbanski, Henry H. Nguyen
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) is a ubiquitously expressed membrane-bound enzyme that mediates shedding of a wide variety of important regulators in inflammation including cytokines and adhesion molecules. Hep
Externí odkaz:
https://doaj.org/article/baa61ac6f41f44bd872a34e0752f00ef
Autor:
Hemant K. Mishra, Kate J. Dixon, Nabendu Pore, Martin Felices, Jeffrey S. Miller, Bruce Walcheck
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are innate cytotoxic lymphocytes that can recognize assorted determinants on tumor cells and rapidly kill these cells. Due to their anti-tumor effector functions and potential for allogeneic use, various NK cell platforms ar
Externí odkaz:
https://doaj.org/article/27002e9de420433699fba065559dac2a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Thorsten Maretzky, Stefan F. Lichtenthaler, Gisela Weskamp, Theresa T. Lu, Sebastien Monette, Jose Lora, Dorjee T.N. Shola, Chingwen Yang, Carl P. Blobel, Thomas M. Li
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 296, 100733-(2021). doi:10.1016/j.jbc.2021.100733
The journal of biological chemistry 296, 100733-(2021). doi:10.1016/j.jbc.2021.100733
A disintegrin and metalloprotease 17 (ADAM17) is a cell-surface metalloprotease that serves as the principle sheddase for tumor necrosis factor α (TNFα), interleukin-6 receptor (IL-6R), and several ligands of the epidermal growth factor receptor (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ddba9cdef79f06d77f3f2a019dddab
https://pubmed.ncbi.nlm.nih.gov/33957124
https://pubmed.ncbi.nlm.nih.gov/33957124
Autor:
Yi Zhao, Eliud Morales Dávila, Xue Li, Beiyu Tang, Ariana I. Rabinowitsch, Jose Manuel Perez-Aguilar, Carl P. Blobel
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12796
The metalloprotease ADAM17 is a key regulator of the TNFα, IL-6R and EGFR signaling pathways. The maturation and function of ADAM17 is controlled by the seven-membrane-spanning proteins iRhoms1 and 2. The functional properties of the ADAM17/iRhom1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c5925afe053ede0d789802750029d1
https://doi.org/10.3390/ijms232112796
https://doi.org/10.3390/ijms232112796
Autor:
Nabendu Pore, Kate Dixon, Hemant K. Mishra, Jeffrey S. Miller, Bruce Walcheck, Martin Felices
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Natural killer (NK) cells are innate cytotoxic lymphocytes that can recognize assorted determinants on tumor cells and rapidly kill these cells. Due to their anti-tumor effector functions and potential for allogeneic use, various NK cell platforms ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b43c967712a30c2e124385a76c28ba
https://www.frontiersin.org/articles/10.3389/fimmu.2021.711621/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.711621/full
Autor:
Jianglei Chen, Yanhong Du, Wenjing Wu, Siribhinya Benyajati, Dibyendu Chakraborty, Yusuke Takahashi, Xiang Ma, Yangxiong Li, Wentao Liang, Jian Xing Ma
Publikováno v:
The Journal of Biological Chemistry
Very low-density lipoprotein receptor (VLDLR) is a multifunctional transmembrane protein. Beyond the function of the full-length VLDLR in lipid transport, the soluble ectodomain of VLDLR (sVLDLR) confers anti-inflammatory and antiangiogenic roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5974b7bf59a8584fad41d82734272403
https://pubmed.ncbi.nlm.nih.gov/34509473
https://pubmed.ncbi.nlm.nih.gov/34509473
Publikováno v:
Pharmacology & Therapeutics
The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has prompted scientists to address an urgent need for defining mechanisms of disease pathology and treatment. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9934ef0c6702914904ddd32cd943ffca
Publikováno v:
Biochimica et Biophysica Acta. Molecular Basis of Disease
SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) also in pregnant women. Infection in pregnancy leads to maternal and placental functional alterations. Pregnant women with vascular defects such as preeclampsia show high susceptibility to SARS-Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f69415503fb233c3dd8f144a7755885
http://europepmc.org/articles/PMC8668602
http://europepmc.org/articles/PMC8668602