Zobrazeno 1 - 10
of 29
pro vyhledávání: '"ADAM, a disintegrin and metalloproteinase"'
Autor:
Antonella D'Amore, Angela Acciarito, Antonino Moschella, Zeeshan Ali, Khouloud Boujnah, Saverio Alberti, Anna Laura Aloisi, Pasquale Simeone, Rossano Lattanzio, Paola Zanna, Giovanna Vacca, Marco Trerotola, Emanuela Guerra, Martina Ceci, Valeria Garbo
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 4, Pp 415-428 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Trop-2 is a transmembrane signal transducer that can induce cancer growth. Using antibody targeting and N-terminal Edman degradation, we show here that Trop-2 undergoes cleavage in the first thyroglobulin domain loop of its extracellular region, betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301cd7c391b29616c20ccc6f7b54ded
http://www.sciencedirect.com/science/article/pii/S1476558621000166
http://www.sciencedirect.com/science/article/pii/S1476558621000166
Publikováno v:
Matrix Biology Plus
Matrix Biology Plus, Vol 12, Iss, Pp 100094-(2021)
Matrix Biology Plus, Vol 12, Iss, Pp 100094-(2021)
Highlights • The endothelial glycocalyx is a ubiquitous intravascular structure essential for vascular homeostasis. • During sepsis, the glycocalyx is degraded via the collective action of a variety of redundant sheddases, the regulation of which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a055ff7791d39ede0280836f32f1d8
http://europepmc.org/articles/PMC8668992
http://europepmc.org/articles/PMC8668992
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 686-695 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 686-695 (2020)
Graphical abstract
Hepatocellular carcinoma (HCC) is an essentially incurable inflammation-related cancer. We have previously shown by network analysis of proteomic data that the flavonoids epigallocatechin gallate (EGCG) and fisetin (FIS) effic
Hepatocellular carcinoma (HCC) is an essentially incurable inflammation-related cancer. We have previously shown by network analysis of proteomic data that the flavonoids epigallocatechin gallate (EGCG) and fisetin (FIS) effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2b7c496c6b1b9ca88af07fd67f672e
https://doi.org/10.1016/j.csbj.2020.03.006
https://doi.org/10.1016/j.csbj.2020.03.006
Autor:
Michelle A. Ozbun
Publikováno v:
Papillomavirus Research
Papillomavirus Research, Vol 7, Iss, Pp 188-192 (2019)
Papillomavirus Research, Vol 7, Iss, Pp 188-192 (2019)
Human papillomaviruses (HPVs), like all PVs, predominantly cause benign tumors, or warts, in stratifying squamous epithelial tissues. Virions are released from apical surfaces of the skin and mucosa and, to initiate a new infection, must utilize a br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7251c6de935a25473ff8355606a1b347
http://europepmc.org/articles/PMC6514438
http://europepmc.org/articles/PMC6514438
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
ADAM and ADAMTS are two large metalloproteinase families involved in numerous physiological processes, such as shedding of cell-surface protein ectodomains and extra-cellular matrix remodelling. Aberrant expression or dysregulation of ADAMs and ADAMT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0150607bd4589c2860f5d1603440359d
http://europepmc.org/articles/PMC8335159
http://europepmc.org/articles/PMC8335159
Autor:
Takeshi Suzuki, Chikako Asada, Hirari Yamahana, Yoshihiro Uto, Risa Takatsuka, Minoru Terashima, Takahisa Takino
Publikováno v:
Biochem Biophys Rep
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101072-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101072-(2021)
Matrix metalloproteinase (MMP)-2 and MMP-9, also known as gelatinases or type IV collagenases, are recognized as major contributors to the proteolytic degradation of extracellular matrix during tumor invasion. Latent MMP-2 (proMMP-2) is activated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e001543e7e8c01d95600f1c24b5b697
https://doi.org/10.1016/j.bbrep.2021.101072
https://doi.org/10.1016/j.bbrep.2021.101072
Autor:
Takehito Asakawa, Takashi Nagaishi, Kiichiro Tsuchiya, Mai Murakami, Tomoaki Mochimaru, Michio Onizawa, Chiharu Sakuma, Ryuichi Okamoto, Hiromasa Ohira, Chikako Saito, Rie Hikichi, Shigeru Oshima, Mamoru Watanabe, Ai Minamidate, Yuichi Hiraoka
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss, Pp 101065-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Ikarugamycin (IK) is an antibiotic which has been reported to have a variety of functions, such as inhibition of clathrin-mediated endocytosis (CME), anti-tumor effects and regulation of the immune system. Whether IK influences cytokine production is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f482f004afe8c745a364c5d5502fc1f4
https://doi.org/10.1016/j.bbrep.2021.101065
https://doi.org/10.1016/j.bbrep.2021.101065
Autor:
Thomas Steuber, Franziska Büscheck, Burkhard Beyer, Maria Christina Tsourlakis, Frank Jacobsen, Asmus Heumann, Stefan Steurer, Till S. Clauditz, Jakob R. Izbicki, Corinna Wittmer, Claudia Hube-Magg, Michael Fitzner, Andrea Hinsch, Andreas M. Luebke, Waldemar Wilczak, Christoph Burdelski, Ronald Simon, Till Krech, Sarah Minner, Thorsten Schlomm, Guido Sauter, Martina Kluth, Imke Thederan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 4, Pp 279-287 (2017)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The A Disintegrin and Metalloproteinase (ADAM) family of endopeptidases plays a role in many solid cancers and includes promising targets for anticancer therapies. Deregulation of ADAM15 has been linked to tumor aggressiveness and cell line studies s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68ac5e92d6d87cc3f75e79a6f751b0a
http://www.sciencedirect.com/science/article/pii/S1476558616301798
http://www.sciencedirect.com/science/article/pii/S1476558616301798
Publikováno v:
Neurobiology of Sleep and Circadian Rhythms
Neurobiology of Sleep and Circadian Rhythms, Vol 5, Iss, Pp 15-36 (2018)
Neurobiology of Sleep and Circadian Rhythms, Vol 5, Iss, Pp 15-36 (2018)
The mammalian circadian and sleep-wake systems are closely aligned through their coordinated regulation of daily activity patterns. Although they differ in their anatomical organization and physiological processes, they utilize overlapping regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9784b59b0d2c00d8e0ea1156b937fff4
https://pubmed.ncbi.nlm.nih.gov/31236509
https://pubmed.ncbi.nlm.nih.gov/31236509
Publikováno v:
Biochemical and Biophysical Research Communications
We have found that A Disintegrin And Metalloproteinase-9 (ADAM9) localises to cell-cell junctions with VE-Cadherin in confluent endothelial monolayers. Co-cultures of cells separately transfected with ADAM9-EGFP or ADAM9-HA showed expression is requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f75aefaae4aeb6625cb7fd2666ef896a
https://pubmed.ncbi.nlm.nih.gov/28928095
https://pubmed.ncbi.nlm.nih.gov/28928095