Zobrazeno 1 - 10
of 168
pro vyhledávání: '"AD pathology"'
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33761- (2024)
Erzhi Wan (EZW), a classic Traditional Chinese Medicine formula, has shown promise as a potential therapeutic option for Alzheimer's disease (AD), yet its mechanism remains elusive. Herein, we employed an integrative in-silico approach to investigate
Externí odkaz:
https://doaj.org/article/4c0cc93803e7409cbb090329e5923222
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24785- (2024)
Background: Scrophulariae Radix (SR) is a commonly used medicinal plant. Alzheimer's disease (AD) is a neurodegenerative disease for which there is no effective treatment. This study aims to initially clarify the potential mechanism of SR in the trea
Externí odkaz:
https://doaj.org/article/a84bd41e9d064da0a1d82e81868b450a
Publikováno v:
Pathogens, Vol 13, Iss 3, p 240 (2024)
Alzheimer’s Disease (AD), a progressive and debilitating condition, is reported to be the most common type of dementia, with at least 55 million people believed to be currently affected. Many causation hypotheses of AD exist, yet the intriguing lin
Externí odkaz:
https://doaj.org/article/9ea41c7828c44b869eb57768f27d31d2
Autor:
Stefan Teipel, Michel J. Grothe
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106070- (2023)
Background: It is not clear to which degree limbic TDP-43 pathology associates with a cholinergic deficit in the absence of Alzheimer's disease (AD) pathology. Objective: Replicate and extend recent evidence on cholinergic basal forebrain atrophy in
Externí odkaz:
https://doaj.org/article/2caa3cea495c4c2e85ee830679a1a88b
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders in the world, but still lack of effective drug treatment. Gynostemma Pentaphyllum (Thunb.) Makino (GpM), a Chinese medicinal herb, plays important ro
Externí odkaz:
https://doaj.org/article/d50588c225414f39b10d328d76688632
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionHeat-clearing and detoxifying Chinese medicines have been documented to have anti-Alzheimer’s disease (AD) activities according to the accumulated clinical experience and pharmacological research results in recent decades. In this study
Externí odkaz:
https://doaj.org/article/899d95cd8f3048daaaba90df1226a4e3
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Background: Numerous benefits of green tea have been reported. However, the effects of green tea on cognitive function remain disputable and the mechanism is still unclear.Objective: To investigate the relationship of green tea consumption with cogni
Externí odkaz:
https://doaj.org/article/283dd58b0cdb4dbd92bffaf3f83123a0
Autor:
Junjie Wu, Syed S. Shahid, Qixiang Lin, Antoine Hone-Blanchet, Jeremy L. Smith, Benjamin B. Risk, Aditya S. Bisht, David W. Loring, Felicia C. Goldstein, Allan I. Levey, James J. Lah, Deqiang Qiu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
While hippocampal atrophy and its regional susceptibility to Alzheimer’s disease (AD) are well reported at late stages of AD, studies of the asymptomatic stage of AD are limited but could elucidate early stage pathophysiology as well as provide pre
Externí odkaz:
https://doaj.org/article/a9a83aa0e3b8457e993050136de93afa
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Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundAlzheimer's disease (AD) is becoming a more prevalent public health issue in today's culture. The experimental study of Coptidis Rhizoma (CR) and its chemical components in AD treatment has been widely reported, but the principle of multi-l
Externí odkaz:
https://doaj.org/article/ab6163d429234ab58a0e4158c9b84ec2