HostSeq: a Canadian whole genome sequencing and clinical data resource

Autor: S Yoo, E Garg, LT Elliott, RJ Hung, AR Halevy, JD Brooks, SB Bull, F Gagnon, CMT Greenwood, JF Lawless, AD Paterson, L Sun, MH Zawati, J Lerner-Ellis, RJS Abraham, I Birol, G Bourque, J-M Garant, C Gosselin, J Li, J Whitney, B Thiruvahindrapuram, J-A Herbrick, M Lorenti, MS Reuter, OO Adeoye, S Liu, U Allen, FP Bernier, CM Biggs, AM Cheung, J Cowan, M Herridge, DM Maslove, BP Modi, V Mooser, SK Morris, M Ostrowski, RS Parekh, G Pfeffer, O Suchowersky, J Taher, J Upton, RL Warren, RSM Yeung, N Aziz, SE Turvey, BM Knoppers, M Lathrop, SJM Jones, SW Scherer, LJ Strug

Publikováno v: BMC Genomic Data, Vol 24, Iss 1, Pp 1-12 (2023)

Abstract HostSeq was launched in April 2020 as a national initiative to integrate whole genome sequencing data from 10,000 Canadians infected with SARS-CoV-2 with clinical information related to their disease experience. The mandate of HostSeq is to

Externí odkaz: https://doaj.org/article/8dd9330e73634673be15f3808eeffdfb

Quantitative Analysis of Cerebral Corrosion Casts from Endoglin+/+ and +/- Mice

Autor: KG terBrugge, AD Paterson, M. Letarte, RJ Mount, MC Wallace, RV Harrison, J. Satomi

Publikováno v: Microscopy and Microanalysis. 8:890-891

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3701228c73c2a0aed0177febd330f75b
https://doi.org/10.1017/s1431927602102650

Autosomal dominant macular dystrophy linked to a chromosome 17 tandem duplication.

Autor: Adele R; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Hussein R; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Tavares E; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Ahmed K; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Di Scipio M; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Charish J; Vision Division, Krembil Research Institute, Toronto, Canada., Liang M; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Monis S; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Tumber A; Department of Ophthalmology and Visual Sciences, Hospital for Sick Children, Toronto, Canada., Chen X; Vision Division, Krembil Research Institute, Toronto, Canada., Paton TA; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Roslin NM; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Eileen C; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Ivakine E; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Sunny NE; Department of Animal and Avian Sciences, University of Maryland, College Park, United States of America., Wilson MD; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Campos E; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Rajala RV; Departments of Ophthalmology, Physiology, and Cell Biology, and Dean McGee, University of Oklahoma Health Sciences Center, Oklahoma City, United States of America., Maynes JT; Department of Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, Canada., Monnier PP; Vision Division, Krembil Research Institute, Toronto, Canada., Paterson AD; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Héon E; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada., Vincent A; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada.

Publikováno v: JCI insight [JCI Insight] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.

Association of Genetically Predicted Skipping of COL4A4 Exon 27 with Hematuria and Albuminuria.

Autor: Lona-Durazo F; Montreal Heart Institute, Montreal, Quebec, Canada.; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Omachi K; Division of Nephrology, Washington University School of Medicine, St. Louis, Missouri.; Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan., Fermin D; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Eichinger F; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Troost JP; Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, Michigan., Lin MH; Division of Nephrology, Washington University School of Medicine, St. Louis, Missouri., Dinsmore IR; Department of Genomic Health, Geisinger, Danville, Pennsylvania., Mirshahi T; Department of Genomic Health, Geisinger, Danville, Pennsylvania., Chang AR; Department of Population Health Sciences, Center for Kidney Health Research, Geisinger, Danville, Pennsylvania.; Department of Nephrology, Geisinger, Danville, Pennsylvania., Miner JH; Division of Nephrology, Washington University School of Medicine, St. Louis, Missouri., Paterson AD; Divisions of Epidemiology and Biostatistics, Dalla Lana School of Public Health, Toronto, Ontario, Canada.; Genetics and Genome Biology, Research Institute at The Hospital for Sick Children, Toronto, Ontario, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada., Barua M; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.; Division of Nephrology, University Health Network, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, Toronto, Ontario, Canada., Gagliano Taliun SA; Montreal Heart Institute, Montreal, Quebec, Canada.; Department of Medicine, Université de Montréal, Montreal, Quebec, Canada.; Department of Neurosciences, Université de Montréal, Montreal, Quebec, Canada.

Publikováno v: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2024 Aug 27. Date of Electronic Publication: 2024 Aug 27.

Analyses of potential causal contributors to increased waist/hip ratio-associated cardiometabolic disease: A combined and sex-stratified Mendelian randomization study.

Autor: Hashemy H; Department of Medicine, University Health Network, Toronto & University of Toronto, Toronto, Ontario, Canada., Nguyen A; Department of Medicine, University Health Network, Toronto & University of Toronto, Toronto, Ontario, Canada., Khafagy R; Department of Medicine, University Health Network, Toronto & University of Toronto, Toronto, Ontario, Canada.; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Divisions of Epidemiology and Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Roshandel D; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada., Paterson AD; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Divisions of Epidemiology and Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Dash S; Department of Medicine, University Health Network, Toronto & University of Toronto, Toronto, Ontario, Canada.

Publikováno v: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Jun; Vol. 26 (6), pp. 2284-2291. Date of Electronic Publication: 2024 Mar 15.