Zobrazeno 1 - 10
of 523
pro vyhledávání: '"ACTOR, P."'
A machine-learnable variational scheme using Gaussian radial basis functions (GRBFs) is presented and used to approximate linear problems on bounded and unbounded domains. In contrast to standard mesh-free methods, which use GRBFs to discretize stron
Externí odkaz:
http://arxiv.org/abs/2410.06219
We present a domain decomposition strategy for developing structure-preserving finite element discretizations from data when exact governing equations are unknown. On subdomains, trainable Whitney form elements are used to identify structure-preservi
Externí odkaz:
http://arxiv.org/abs/2406.05571
Causal representation learning algorithms discover lower-dimensional representations of data that admit a decipherable interpretation of cause and effect; as achieving such interpretable representations is challenging, many causal learning algorithms
Externí odkaz:
http://arxiv.org/abs/2310.18471
Publikováno v:
Frontiers in Mechanical Engineering, Vol 10 (2024)
Representation learning algorithms are often used to extract essential features from high-dimensional datasets. These algorithms commonly assume that such features are independent. However, multimodal datasets containing complementary information oft
Externí odkaz:
https://doaj.org/article/4c3c52496fb6436d8c9d06a7d2d97175
Using neural networks to solve variational problems, and other scientific machine learning tasks, has been limited by a lack of consistency and an inability to exactly integrate expressions involving neural network architectures. We address these lim
Externí odkaz:
http://arxiv.org/abs/2110.14055
Autor:
Celaya, Adrian, Actor, Jonas A., Muthusivarajan, Rajarajeswari, Gates, Evan, Chung, Caroline, Schellingerhout, Dawid, Riviere, Beatrice, Fuentes, David
Medical imaging deep learning models are often large and complex, requiring specialized hardware to train and evaluate these models. To address such issues, we propose the PocketNet paradigm to reduce the size of deep learning models by throttling th
Externí odkaz:
http://arxiv.org/abs/2104.10745
Autor:
Samantha S. Olah, Dean J. Kareemo, William C. Buchta, Brooke L. Sinnen, Carley N. Miller, Hannah S. Actor-Engel, Sara E. Gookin, Christina S. Winborn, Mason S. Kleinjan, Kevin C. Crosby, Jason Aoto, Katharine R. Smith, Matthew J. Kennedy
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113331- (2023)
Summary: Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic neurotransmitter release sites. While spatial coordination between pre- and postsynaptic elemen
Externí odkaz:
https://doaj.org/article/3444965cf8894b45b28692c79eca5faf
Autor:
Harrison J. Ramsay, Sara E. Gookin, Austin M. Ramsey, Dean J. Kareemo, Kevin C. Crosby, Dominik G. Stich, Samantha S. Olah, Hannah S. Actor-Engel, Katharine R. Smith, Matthew J. Kennedy
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Postsynaptic neurotransmitter receptors and their associated scaffolding proteins assemble into discrete, nanometer-scale subsynaptic domains (SSDs) within the postsynaptic membrane at both excitatory and inhibitory synapses. Intriguingly, postsynapt
Externí odkaz:
https://doaj.org/article/0a611978cc574cd884372c1cb950f914
Autor:
Actor, Jonas, Knepley, Matthew G.
Kolmogorov famously proved that multivariate continuous functions can be represented as a superposition of a small number of univariate continuous functions, $$ f(x_1,\dots,x_n) = \sum_{q=0}^{2n+1} \chi^q \left( \sum_{p=1}^n \psi^{pq}(x_p) \right).$$
Externí odkaz:
http://arxiv.org/abs/1712.08286
Autor:
Nandadeva Lokugamage, Imran H. Chowdhury, Ronald J. Biediger, Robert V. Market, Sayadeth Khounlo, Navin D. Warier, Shen-An Hwang, Jeffrey K. Actor, Darren G. Woodside, Upendra Marathi, Peter Vanderslice, Nisha Jain Garg
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract The development of suitable safe adjuvants to enhance appropriate antigen-driven immune responses remains a challenge. Here we describe the adjuvant properties of a small molecule activator of the integrins αLβ2 and α4β1, named 7HP349, w
Externí odkaz:
https://doaj.org/article/fa56993f549b4cbda0b8eb8236c01b18