Zobrazeno 1 - 10
of 87 897
pro vyhledávání: '"ACTIVE-SITE"'
Autor:
Rabea Voget, Julian Breidenbach, Tobias Claff, Alexandra Hingst, Katharina Sylvester, Christian Steinebach, Lan Phuong Vu, Renato H. Weiße, Ulrike Bartz, Norbert Sträter, Christa E. Müller, Michael Gütschow
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2349-2357 (2024)
A titrant for the SARS-CoV-2 main protease (Mpro) was developed that enables, for the first time, the exact determination of the concentration of the enzymatically active Mpro by active-site titration. The covalent binding mode of the tetrapeptidic t
Externí odkaz:
https://doaj.org/article/58da7d67bdec41a39ad53783d3a36b34
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract Iron single‐atom catalysts (SACs) have garnered increasing attention as highly efficient catalysts for the oxygen reduction reaction (ORR), yet their performance in practical devices remains suboptimal due to the low density of accessible
Externí odkaz:
https://doaj.org/article/0bd3e325650e426aadcb2e97efe850a4
Publikováno v:
Carbon Resources Conversion, Vol 7, Iss 3, Pp 100222- (2024)
In this study, we aimed to synthesise and evaluate the antimicrobial activity of sulphanilamide-condensed pyrimidine derivatives. The compounds were synthesised using a one-pot, three-component reaction. The structures of the synthesised compounds we
Externí odkaz:
https://doaj.org/article/912b132446334bec80fa3cfe6edadfa7
Publikováno v:
Carbon Energy, Vol 6, Iss 8, Pp n/a-n/a (2024)
Abstract Electrocatalytic water splitting has been identified as a potential candidate for producing clean hydrogen energy with zero carbon emission. However, the sluggish kinetics of oxygen evolution reaction on the anode side of the water‐splitti
Externí odkaz:
https://doaj.org/article/5ab5b86b21134ad6a2b27b5a34addc0a
Autor:
Preety Panwar, Jacob Bastholm Olesen, Galia Blum, Jean-Marie Delaisse, Kent Søe, Dieter Brömme
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cathepsin K (CatK), an essential collagenase in osteoclasts (OCs), is a potential therapeutic target for the treatment of osteoporosis. Using live-cell imaging, we monitored the bone resorptive behaviour of OCs during dose-dependent inhibiti
Externí odkaz:
https://doaj.org/article/92cb3c72ac144f1391fde56b99a57085
Publikováno v:
Nano-Micro Letters, Vol 16, Iss 1, Pp 1-24 (2024)
Highlights Mechanistic understandings of metal-free carbon thermocatalysis and electrocatalysis from the viewpoint of model method are summarized. Active sites and reaction mechanisms are discussed with a focus on in-situ techniques and 2D structure
Externí odkaz:
https://doaj.org/article/1fda428f3df34fdfb232cbd0b868ea35
Publikováno v:
Eng, Vol 5, Iss 1, Pp 91-103 (2024)
Protein engineering is the design and modification of protein structures to optimize their functions or create novel functionalities for applications in biotechnology, medicine or industry. It represents an essential scientific solution for many of t
Externí odkaz:
https://doaj.org/article/918843479472405ba371b252b1f1705c
Publikováno v:
Fuel Processing Technology, Vol 261, Iss , Pp 108106- (2024)
Developing highly efficient single-atom catalysts (SACs) for electrocatalytic carbon dioxide reduction reaction (CO2RR) is a promising approach to promoting carbon neutrality. However, challenges such as low activity, selectivity and high costs hinde
Externí odkaz:
https://doaj.org/article/692317f91a1a4f0582d229bbb7d5ef06
Publikováno v:
ChemElectroChem, Vol 11, Iss 10, Pp n/a-n/a (2024)
Abstract The demand for hydrogen production technology to replace fossil fuels and address the global climate crisis has become one of the most urgent tasks in the modern era. Among the promising breakthroughs, electrochemical water splitting using r
Externí odkaz:
https://doaj.org/article/363c2e7b77744ee1b51e5d5f8b959d3a