Zobrazeno 1 - 2
of 2
pro vyhledávání: '"ACT, Atypical cartilaginous tumor"'
Autor:
Hans J. Baelde, Yvonne de Jong, Alwine B. Kruisselbrink, Judith V.M.G. Bovée, Gaia Alberti, Ruben D. Addie, Ivo Que
Publikováno v:
Journal of Bone Oncology
Journal of Bone Oncology, Vol 15, Iss, Pp-(2019)
Journal of Bone Oncology, 15
Journal of Bone Oncology, Vol 15, Iss, Pp-(2019)
Journal of Bone Oncology, 15
Background: Chondrosarcomas are malignant cartilage-producing tumors showing mutations and changes in gene expression in metabolism related genes. In this study, we aimed to explore the metabolome and identify targetable metabolic vulnerabilities in
Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway.
Autor:
Addie RD; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., de Jong Y; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Alberti G; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Kruisselbrink AB; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Que I; Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands., Baelde H; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands., Bovée JVMG; Department of Pathology, Leiden University Medical Centre, Leiden, the Netherlands.
Publikováno v:
Journal of bone oncology [J Bone Oncol] 2019 Jan 29; Vol. 15, pp. 100222. Date of Electronic Publication: 2019 Jan 29 (Print Publication: 2019).