Zobrazeno 1 - 10
of 14
pro vyhledávání: '"ACLY ATP citrate lyase"'
Autor:
Balakrishna L. Lokeshwar, Su Hyeong Kim, Shivendra V. Singh, Krishna B. Singh, Eun-Ryeong Hahm
Publikováno v:
Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 10, Iss 3, Pp 188-197 (2020)
Journal of Traditional and Complementary Medicine, Vol 10, Iss 3, Pp 188-197 (2020)
Prior research argues for a role of increased de novo fatty acid synthesis in pathogenesis of prostate adenocarcinoma, which remains a leading cause of cancer-associated mortality in American men. A safe and effective inhibitor of fatty acid synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243c1f07ad39b092a389000f579ecb5f
http://europepmc.org/articles/PMC7340880
http://europepmc.org/articles/PMC7340880
Autor:
Jennifer E. Gallagher, Dorothy Kisielewski, John F. Dillon, Shaun V. Walsh, Diane Cassidy, David J. Harrison, Ritu Sharma, Tadashi Honda, John D. Hayes, Alison D. McNeilly, Michael L.J. Ashford, Albena T. Dinkova-Kostova, Rory J. McCrimmon
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)
Background & Aims Nonalcoholic steatohepatitis (NASH) is associated with oxidative stress. We surmised that pharmacologic activation of NF-E2 p45-related factor 2 (Nrf2) using the acetylenic tricyclic bis(cyano enone) TBE-31 would suppress NASH becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdd8de56b5ba950a8c970d72cce7012
https://doi.org/10.1016/j.jcmgh.2017.11.016
https://doi.org/10.1016/j.jcmgh.2017.11.016
Publikováno v:
The Journal of Biological Chemistry
Mitochondria are critical for regulation of the activation, differentiation, and survival of macrophages and other immune cells. In response to various extracellular signals, such as microbial or viral infection, changes to mitochondrial metabolism a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b40b8a29dfcab6952141869277a440
https://doi.org/10.1016/j.jbc.2021.100904
https://doi.org/10.1016/j.jbc.2021.100904
Autor:
Robert T. Kennedy, Michael J. MacDonald, Charles F. Burant, Melissa J. Longacre, Mahmoud A. El Azzouny, Israrul H. Ansari
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 10, Pp 980-987 (2016)
Molecular Metabolism, Vol 5, Iss 10, Pp 980-987 (2016)
Objective Glucose-stimulated insulin secretion in pancreatic beta cells requires metabolic signals including the generation of glucose-derived short chain acyl-CoAs in the cytosol from mitochondrially-derived metabolites. One concept of insulin secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449a905936b693b58c6c575c1c722dd0
https://doi.org/10.1016/j.molmet.2016.07.011
https://doi.org/10.1016/j.molmet.2016.07.011
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 5, Iss, Pp 598-607 (2018)
Toxicology Reports, Vol 5, Iss, Pp 598-607 (2018)
Graphical abstract
Highlights • Capsaicinoids (CAPs) are active compounds in Capsicum fruits. • CAPs have anti-inflammatory and antioxidant properties. • CAPs with regular exercise may enhance lipid metabolism. • CAPs down-regulate muscl
Highlights • Capsaicinoids (CAPs) are active compounds in Capsicum fruits. • CAPs have anti-inflammatory and antioxidant properties. • CAPs with regular exercise may enhance lipid metabolism. • CAPs down-regulate muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5662d8d52b26aec118984ecdb36a17bb
https://pubmed.ncbi.nlm.nih.gov/29854630
https://pubmed.ncbi.nlm.nih.gov/29854630
Autor:
Luisa M.P. Valente, Marta Conde-Sieira, Emilio Salas-Leiton, Nicole Francesca Pelusio, Marta M. Duarte, José L. Soengas
Publikováno v:
British Journal of Nutrition.
Four isolipidic and isoenergetic diets with different protein:carbohydrate (CH) contents (48:38, 52:34, 56:30, 60:26) were fed to juvenile Senegalese sole (22·01 (sem0·01) g) during 104 d. Oral glucose tolerance tests were performed at the beginnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eff14929f32586f18887c2d336ffcab
https://doi.org/10.1017/s0007114516001057
https://doi.org/10.1017/s0007114516001057
Autor:
Boris N. Kholodenko, Natalia Volinsky, Cormac McCarthy, Nina Saban, Mariko Okada-Hatakeyama, Alex von Kriegsheim, Walter Kolch
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 35, Iss 2, p e00178 (2015)
Bioscience Reports, Vol 35, Iss 2, p e00178 (2015)
In MCF-7 breast cancer cells epidermal growth factor (EGF) induces cell proliferation, whereas heregulin (HRG)/neuregulin (NRG) induces irreversible phenotypic changes accompanied by lipid accumulation. Although these changes in breast cancer cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ef4589932267100ca4347d61ac0ead
https://doi.org/10.1042/bsr20140172
https://doi.org/10.1042/bsr20140172
Autor:
Paul B; Biotech Research & Innovation Center (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lewinska M; Biotech Research & Innovation Center (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Andersen JB; Biotech Research & Innovation Center (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2022 Mar 26; Vol. 4 (6), pp. 100479. Date of Electronic Publication: 2022 Mar 26 (Print Publication: 2022).
Autor:
Kim SH; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Singh KB; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Hahm ER; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Lokeshwar BL; Georgia Cancer Center and Department of Medicine, Augusta University, Augusta, GA, USA., Singh SV; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Publikováno v:
Journal of traditional and complementary medicine [J Tradit Complement Med] 2020 Feb 07; Vol. 10 (3), pp. 188-197. Date of Electronic Publication: 2020 Feb 07 (Print Publication: 2020).
Autor:
Kovalic AJ; Wake Forest Baptist Medical Center, Department of Internal Medicine, Winston-Salem, NC, United States., Banerjee P; University of Memphis, School of Public Health, Division of Epidemiology, Biostatistics, and Environmental Health, Memphis, TN, United States., Tran QT; University of Tennessee Health Science Center, Department of Preventive Medicine, Memphis, TN, United States., Singal AK; University of Alabama at Birmingham, Department of Medicine, Division of Gastroenterology and Hepatology, Birmingham, AL, United States., Satapathy SK; University of Tennessee Health Science Center, Methodist University Hospital Transplant Institute, Memphis, TN, United States.
Publikováno v:
Journal of clinical and experimental hepatology [J Clin Exp Hepatol] 2018 Dec; Vol. 8 (4), pp. 390-402. Date of Electronic Publication: 2018 Apr 25.