Zobrazeno 1 - 10
of 98
pro vyhledávání: '"ACKR2"'
Publikováno v:
In International Immunopharmacology 25 December 2024 143 Part 2
Autor:
Martyna Szpakowska, Giulia D’Uonnolo, Rafael Luís, Ana Alonso Bartolomé, Marcus Thelen, Daniel F. Legler, Andy Chevigné
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Atypical chemokine receptors (ACKRs) form a small subfamily of receptors (ACKR1–4) unable to trigger G protein-dependent signaling in response to their ligands. They do, however, play a crucial regulatory role in chemokine biology by capturing, sca
Externí odkaz:
https://doaj.org/article/8e49bcf050c243f79bcc7daea35cb726
Autor:
Alessandro Vacchini, Elisa Maffioli, Dario Di Silvestre, Cinzia Cancellieri, Samantha Milanesi, Simona Nonnis, Sabrina Badanai, Pierluigi Mauri, Armando Negri, Massimo Locati, Gabriella Tedeschi, Elena Monica Borroni
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
ACKR2 is an atypical chemokine receptor which is structurally uncoupled from G proteins and is unable to activate signaling pathways used by conventional chemokine receptors to promote cell migration. Nonetheless, ACKR2 regulates inflammatory and imm
Externí odkaz:
https://doaj.org/article/bde15963e014423c9585dbe4db42066b
Autor:
Giulia D’Uonnolo, Nathan Reynders, Max Meyrath, Dayana Abboud, Tomasz Uchański, Toon Laeremans, Brian F. Volkman, Bassam Janji, Julien Hanson, Martyna Szpakowska, Andy Chevigné
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The chemokine receptor CXCR3 plays a critical role in immune cell recruitment and activation. CXCR3 exists as two main isoforms, CXCR3-A and CXCR3-B, resulting from alternative splicing. Although the two isoforms differ only by the presence of an N-t
Externí odkaz:
https://doaj.org/article/97a267f9626b47b594598c4e259d2560
Autor:
Arezoo Gowhari Shabgah, Farhad Jadidi-Niaragh, Hamed Mohammadi, Farnoosh Ebrahimzadeh, Maziar Oveisee, Abbas Jahanara, Jamshid Gholizadeh Navashenaq
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chemokines exert crucial roles in inducing immune responses through ligation to their canonical receptors. Besides these receptors, there are other atypical chemokine receptors (ACKR1–4) that can bind to a wide range of chemokines and carry out var
Externí odkaz:
https://doaj.org/article/8a4d8e18c68646d38b751e70b202c0b9
Akademický článek
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Akademický článek
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Autor:
Alessandro Vacchini, Cinzia Cancellieri, Samantha Milanesi, Sabrina Badanai, Benedetta Savino, Francesco Bifari, Massimo Locati, Raffaella Bonecchi, Elena Monica Borroni
Publikováno v:
Vaccines, Vol 8, Iss 3, p 542 (2020)
The atypical chemokine receptor ACKR2, formerly named D6, is a scavenger chemokine receptor with a non-redundant role in the control of inflammation and immunity. The scavenging activity of ACKR2 depends on its trafficking properties, which require a
Externí odkaz:
https://doaj.org/article/d13f68dbc089452082d753d6d63f170e
Autor:
Gerard J. Graham, Megan K. L. MacLeod, Gillian J. Wilson, Samantha Love, Christopher A.H. Hansell, Marieke Pingen
Publikováno v:
European Journal of Immunology
Analysis of chemokine receptor, and atypical chemokine receptor, expression is frequently hampered by the lack of availability of high‐quality antibodies and the species specificity of those that are available. We have previously described methodol
Akademický článek
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