Zobrazeno 1 - 10
of 3 983
pro vyhledávání: '"ACE2 protein, human"'
Autor:
Nicholas C. Wu, Xueyong Zhu, Marit J. van Gils, Jakob Kreye, Chang-Chun D Lee, Linghang Peng, Hejun Liu, Meng Yuan, Abigail M. Jackson, Dennis R. Burton, Andrew B. Ward, Rogier W. Sanders, David Nemazee, S. Momsen Reincke, Harald Prüss, Ian A. Wilson, Deli Huang
Publikováno v:
Science 373(6556), 818-823 (2021). doi:10.1126/science.abh1139
bioRxiv
article-version (status) pre
article-version (number) 1
Science, 373(6556), 818-823. American Association for the Advancement of Science
Science (New York, N.y.)
bioRxiv
article-version (status) pre
article-version (number) 1
Science, 373(6556), 818-823. American Association for the Advancement of Science
Science (New York, N.y.)
The protective efficacy of neutralizing antibodies (nAbs) elicited during natural infection with SARS-CoV-2 and by vaccination based on its spike protein has been compromised with emergence of the recent SARS-CoV-2 variants. Residues E484 and K417 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a44f112f84d84b18800a45c2c75d8b9
http://www.scopus.com/inward/record.url?scp=85112522453&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85112522453&partnerID=8YFLogxK
Autor:
Badiu, Dumitru Cristinel, Popescu, Gabriel Cristian, Zgura, Anca, Stanciu, Adriana Mercan, Dodot, Mihai Daniel, Mehedintu, Claudia, Toma, Letitia, Razvan, Simu, Bacinschi, Xenia, Haineala, Bogdan
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
BACKGROUND Thyroiditis is an important extrahepatic association in chronic hepatitis C virus (HCV) infection. There have been reports of an association between SARS-CoV-2 infection and the onset or re-activation of autoimmune hypothyroidism. Therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10e7fed4aaf8c43e6a5b191f2bb4bea
https://doi.org/10.12659/msm.935075
https://doi.org/10.12659/msm.935075
Autor:
Prelli Bozzo, Caterina, Nchioua, Rayhane, Volcic, Meta, Koepke, Lennart, Krüger, Jana, Schütz, Desiree, Heller, Sandra, Stürzel, Christina M., Kmiec, Dorota, Conzelmann, Carina, Müller, Janis, Zech, Fabian, Braun, Elisabeth, Groß, Rüdiger, Wettstein, Lukas, Weil, Tatjana, Weiß, Johanna, Diofano, Federica, Rodríguez Alfonso, Armando A., Wiese, Sebastian, Sauter, Daniel, Münch, Jan, Goffinet, Christine, Catanese, Alberto, Schön, Michael, Boeckers, Tobias M., Stenger, Steffen, Sato, Kei, Just, Steffen, Kleger, Alexander, Sparrer, Konstantin M. J., Kirchhoff, Frank
Publikováno v:
Nature Communications 12(1), 4584 (2021). doi:10.1038/s41467-021-24817-y
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) can restrict viral pathogens, but pro- and anti-viral activities have been reported for coronaviruses. Here, we show that artificial overexpression of IFITMs blocks SARS-CoV-2 infection. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc49410437957521bf8a06e7e4be82f2
https://pub.dzne.de/record/162717
https://pub.dzne.de/record/162717
Autor:
Julius Hoffmann, Laura Stöffler, Christian Drosten, Ian A. Wilson, Stefan Hippenstiel, Niels von Wardenburg, Jakob Trimpert, Xueyong Zhu, Dietmar Schmitz, Scott van Hoof, Andreas C. Hocke, Florian Kurth, Marcel A. Müller, Lucie Y Li, Hejun Liu, Leif E. Sander, Christiana Franke, Daria Vladimirova, Chang-Chun D Lee, Anja Richter, Marie Luisa Schmidt, Kristina Dietert, Elisa Sanchez-Sendin, Jakob Kreye, Karl Skriner, Harald Prüss, Lara Maria Jeworowski, Martin Witzenrath, Marie A Homeyer, Nikolaus Osterrieder, Nicholas C. Wu, Daniel Wendisch, Victor M. Corman, Paula Charlotte Barthel, Matthias Endres, Luca D. Bertzbach, Azza Abdelgawad, Meng Yuan, Norbert Suttorp, S. Momsen Reincke, Markus Höltje, Tatjana Schwarz, Hans Christian Kornau, Achim D. Gruber
Publikováno v:
Cell
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed characterization of virus-neutralizing antibodies and target epitopes is needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5418ec544a5ad15fbfd4125ba4fd2f9d
http://europepmc.org/articles/PMC7510528
http://europepmc.org/articles/PMC7510528
Autor:
Shu Liu, Annika Hornberger, Katerina Konstantoulea, Philip Denner, Stefan F. Lichtenthaler, Stefanie-Elisabeth Heumüller, Lydia Paulsen, André Hossinger, Joost Schymkowitz, Frederic Rousseau, Ina Vorberg, Manuela Neumann, Oleksandra Buravlova, Stephan A. Müller
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications 12(1), 5739 (2021). doi:10.1038/s41467-021-25855-2
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications 12(1), 5739 (2021). doi:10.1038/s41467-021-25855-2
Protein aggregates associated with neurodegenerative diseases have the ability to transmit to unaffected cells, thereby templating their own aberrant conformation onto soluble homotypic proteins. Proteopathic seeds can be released into the extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c267871c21edbc58285a17a04aad283d
https://pubmed.ncbi.nlm.nih.gov/34667166
https://pubmed.ncbi.nlm.nih.gov/34667166
Autor:
Teemu Smura, Frederic A. Meunier, Minou Djannatian, Jonas Franz, Martin Sebastian Winkler, Christine Stadelmann, Leonora Szirovicza, Brit Mollenhauer, Ari Helenius, Pamela Österlund, Olli Vapalahti, Tuğberk Kaya, Sarah J. Butcher, Maria Anastasina, Lev Levanov, Ravi Ojha, Suvi Kuivanen, Ludovico Cantuti-Castelvetri, Mikael Simons, Hannimari Kallio-Kokko, Ozgun Gokce, Giuseppe Balistreri, Katri Kallio, Merja Joensuu, Liliana D. Pedro, Allan Tobi, Franziska van der Meer, Tambet Teesalu, Jussi Hepojoki
Publikováno v:
Science
Science, 370 (6518)
Science (New York, N.y.)
Science / Science now 370(6518), 856-860 (2020). doi:10.1126/science.abd2985
Signal Transduction and Targeted Therapy
Science, 370 (6518)
Science (New York, N.y.)
Science / Science now 370(6518), 856-860 (2020). doi:10.1126/science.abd2985
Signal Transduction and Targeted Therapy
Another host factor for SARS-CoV-2 Virus-host interactions determine cellular entry and spreading in tissues. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the earlier SARS-CoV use angiotensin-converting enzyme 2 (ACE2) as a recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d602d02c0f3dd0c2860bc58f052583
Autor:
Linghang Peng, Fangzhu Zhao, Meng Yuan, Xueyong Zhu, Dennis R. Burton, Hejun Liu, Nicholas C. Wu, Chang-Chun D Lee, Marit J. van Gils, David Nemazee, Deli Huang, Sandhya Bangaru, Ian A. Wilson, Hans Christian Kornau, Shawn Barman, Harald Prüss, Rogier W. Sanders, Jakob Kreye, S. Momsen Reincke, Andrew B. Ward
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
Cell host & microbe, 29(5), 806-818.e6. Cell Press
Cell host and microbe 29(5), 806-818.e6 (2021). doi:10.1016/j.chom.2021.04.005
Cell Host & Microbe
article-version (status) pre
article-version (number) 1
Cell host & microbe, 29(5), 806-818.e6. Cell Press
Cell host and microbe 29(5), 806-818.e6 (2021). doi:10.1016/j.chom.2021.04.005
Cell Host & Microbe
Coronaviruses have caused several human epidemics and pandemics including the ongoing coronavirus disease 2019 (COVID-19). Prophylactic vaccines and therapeutic antibodies have already shown striking effectiveness against COVID-19. Nevertheless, conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf08c7509dedd958cc92d18c46463d3
https://doi.org/10.1016/j.chom.2021.04.005
https://doi.org/10.1016/j.chom.2021.04.005
Publikováno v:
Cell Reports
Cell Reports, Vol 32, Iss 12, Pp 108175-(2020)
Cell reports 32(12), 108175 (2020). doi:10.1016/j.celrep.2020.108175
SSRN
bioRxiv
article-version (status) pre
article-version (number) 2
Cell Reports, Vol 32, Iss 12, Pp 108175-(2020)
Cell reports 32(12), 108175 (2020). doi:10.1016/j.celrep.2020.108175
SSRN
bioRxiv
article-version (status) pre
article-version (number) 2
To predict the tropism of human coronaviruses, we profile 28 SARS-CoV-2 and coronavirus-associated receptors and factors (SCARFs) using single-cell transcriptomics across various healthy human tissues. SCARFs include cellular factors both facilitatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53de96471dee3f2ce03610e0ebd50321
http://europepmc.org/articles/PMC7470764
http://europepmc.org/articles/PMC7470764
Autor:
Lou, Pei1 (AUTHOR), Fang, An1 (AUTHOR), Zhao, Wanqing1 (AUTHOR), Yao, Kuanda1 (AUTHOR), Yang, Yusheng1 (AUTHOR), Hu, Jiahui1 (AUTHOR) hu.jiahui@imicams.ac.cn
Publikováno v:
Journal of Medical Internet Research. 2023, Vol. 25 Issue 1, p1-21. 21p.
Autor:
Zhu, An1,2,3 (AUTHOR), Liu, Min1 (AUTHOR), Li, Yang4 (AUTHOR), Lei, Qing5 (AUTHOR), Wu, Qiaoyi6 (AUTHOR), Lin, Mingxi1 (AUTHOR), Lai, Danyun4 (AUTHOR), Lu, Linfang1 (AUTHOR), Yu, Siqi1 (AUTHOR), Guo, Shujuan4 (AUTHOR), Jiang, Hewei4 (AUTHOR), Hou, Hongyan7 (AUTHOR), Zheng, Yunxiao4 (AUTHOR), Wang, Xuening4 (AUTHOR), Ma, Mingliang4 (AUTHOR), Zhang, Bo7 (AUTHOR), Chen, Hong4 (AUTHOR), Xue, Junbiao4 (AUTHOR), Zhang, Hainan4 (AUTHOR), Qi, Huan4 (AUTHOR)
Publikováno v:
Journal of Clinical Medicine. Oct2022, Vol. 11 Issue 19, p5974. 16p.