Zobrazeno 1 - 10
of 98
pro vyhledávání: '"ACC, acetyl CoA carboxylase"'
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic total cholesterol (TC) and total triglyceride (TG) accumulation. In our previous study, we found that rats treated with hyperoside became re
Introduction Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic total cholesterol (TC) and total triglyceride (TG) accumulation. In our previous study, we found that rats treated with hyperoside became re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2bd34a875a308c3012404fcb1667cc
https://doi.org/10.1016/j.jare.2021.06.001
https://doi.org/10.1016/j.jare.2021.06.001
Autor:
Yuxiao Liu, Xiaozhen Dai, Xiao-Lin Liu, Aoyuan Cui, Feng Shen, Feng-Zhi Xin, Weitong Su, Jian-Gao Fan, Yamei Han, Ze-Hua Zhao, Feifei Zhang, Yaqian Xue, Yu Li, Genxiang Cai, Zhengshuai Liu, Zi-Xuan Wang, Qin Pan, Jinyun Bai, Zhimin Hu, Tian-Yi Ren, Fengguang Ma, Da Zhou
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)
Background and Aims Butyric acid is an intestinal microbiota-produced short-chain fatty acid, which exerts salutary effects on alleviating nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism of butyrate on regulating hepatic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4e846e48b3e395486746888e372063
https://doi.org/10.1016/j.jcmgh.2021.05.006
https://doi.org/10.1016/j.jcmgh.2021.05.006
Autor:
Chang Hwa Jung, Hyunjung Lee, Hyo-Deok Seo, Jiyun Ahn, Young In Kim, Tae-Youl Ha, Seung Yeon Ha
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1201-1213 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The development of nonalcoholic fatty liver disease (NAFLD) can be modulated by microRNAs (miRNA). Dietary polyphenols modulate the expression of miRNA such as miR-467b-3p in the liver. In addition, 6-gingerol (6-G), the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3294865d4fb01bb2374fab59ed3691
http://www.sciencedirect.com/science/article/pii/S2352345X21001223
http://www.sciencedirect.com/science/article/pii/S2352345X21001223
Autor:
Klaus Schughart, Diana Cabrera, Heike Kollmus, Carolin Pilzner, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez
Publikováno v:
The Journal of biological chemistry
United States
The Journal of Biological Chemistry
United States
The Journal of Biological Chemistry
Influenza A virus (IAV) infection casts a significant burden on society. It has particularly high morbidity and mortality rates in patients suffering from metabolic disorders. The aim of this study was to relate metabolic changes with IAV susceptibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35df79d0e1826add7a81f0ba6216551f
https://hdl.handle.net/10033/623093
https://hdl.handle.net/10033/623093
Autor:
Naoya Sakamoto, Koji Nakagawa, Goki Suda, Ayaka Asano, Masanobu Kobayashi, Mitsuteru Natsuizaka, Shunsuke Ohnishi, Hiroshi Takeda, Osamu Maehara
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 6, Pp 545-556 (2019)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 6, Pp 545-556 (2019)
CD133 is a cellular surface protein, which has been reported to be a cancer stem cell marker, and thus is considered a potential target for cancer treatment. Metformin, one of the biguanides used for the treatment of diabetes, is also known to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7622a72464a68bd5e5a7720bad47e569
https://doi.org/10.1016/j.neo.2019.03.007
https://doi.org/10.1016/j.neo.2019.03.007
Autor:
Younes Achouri, Joseph P. Dewulf, Emile Van Schaftingen, Stéphanie Paquay, Etienne Marbaix, Guido T. Bommer
Publikováno v:
The Journal of Biological Chemistry
The Journal of biological chemistry, Vol. 297, no.4, p. 101083 (2021)
The Journal of biological chemistry, Vol. 297, no.4, p. 101083 (2021)
The cytosolic enzyme ethylmalonyl-CoA decarboxylase (ECHDC1) decarboxylates ethyl- or methyl-malonyl-CoA, two side-products of acetyl-CoA carboxylase. These CoA derivatives can be used to synthesize a subset of branched-chain fatty acids (FAs). We pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b97fc024070caa6e86136ac1563a523
https://pubmed.ncbi.nlm.nih.gov/34419447
https://pubmed.ncbi.nlm.nih.gov/34419447
Publikováno v:
JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
International audience; Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease worldwide. It is characterised by steatosis, liver inflammation, hepatocellular injury and progressive fibrosis. Several preclinical models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31673956635c337dc60791ff712432
https://pubmed.ncbi.nlm.nih.gov/34667947
https://pubmed.ncbi.nlm.nih.gov/34667947
Publikováno v:
Metabolism Open, Vol 9, Iss, Pp 100086-(2021)
Metabolism Open
Metabolism Open
Background In our recent study using [U–13C3]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol (1,3PDO) and 3-hydroxypropio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675290128f116ea040e00c4c3e286fbe
http://www.sciencedirect.com/science/article/pii/S2589936821000104
http://www.sciencedirect.com/science/article/pii/S2589936821000104
Autor:
Emile Levy, Nickolas Auclair, Lena Ahmarani, Jean-François Beaulieu, Noël Peretti, Nathalie Patey, Schohraya Spahis, Alain T. Sané
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, Vol 62, Iss, Pp 100085-(2021)
Journal of Lipid Research, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, Vol 62, Iss, Pp 100085-(2021)
International audience; Chylomicron retention disease (CRD) is an autosomal recessive disorder associated with biallelic Sar1b mutations leading to defects in intracellular chylomicron (CM) trafficking and secretion. To date, a direct cause-effect re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437c6d76490d2b00b616f9ab5275cf52
https://doi.org/10.1016/j.jlr.2021.100085
https://doi.org/10.1016/j.jlr.2021.100085
Autor:
Yan Gao, Ruibing Chen, Zhenwen Zhao, Xinyu Guan, Hao Wang, Yali Zhang, Xiangyang Zhang, Xing Li
Publikováno v:
Molecular & Cellular Proteomics : MCP
Long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is upregulated in various cancers, and its overexpression is associated with tumor growth and metastasis. MALAT1 has been recognized as a key player in the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b330e561ef21a94663bda07e49baef7
https://pubmed.ncbi.nlm.nih.gov/34478876
https://pubmed.ncbi.nlm.nih.gov/34478876