Zobrazeno 1 - 10
of 98
pro vyhledávání: '"ACC, Acetyl CoA carboxylase"'
Publikováno v:
Journal of Advanced Research
Graphical abstract
Introduction Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic total cholesterol (TC) and total triglyceride (TG) accumulation. In our previous study, we found that rats treated with hyperoside became re
Introduction Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic total cholesterol (TC) and total triglyceride (TG) accumulation. In our previous study, we found that rats treated with hyperoside became re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2bd34a875a308c3012404fcb1667cc
https://doi.org/10.1016/j.jare.2021.06.001
https://doi.org/10.1016/j.jare.2021.06.001
Autor:
Yuxiao Liu, Xiaozhen Dai, Xiao-Lin Liu, Aoyuan Cui, Feng Shen, Feng-Zhi Xin, Weitong Su, Jian-Gao Fan, Yamei Han, Ze-Hua Zhao, Feifei Zhang, Yaqian Xue, Yu Li, Genxiang Cai, Zhengshuai Liu, Zi-Xuan Wang, Qin Pan, Jinyun Bai, Zhimin Hu, Tian-Yi Ren, Fengguang Ma, Da Zhou
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)
Background and Aims Butyric acid is an intestinal microbiota-produced short-chain fatty acid, which exerts salutary effects on alleviating nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism of butyrate on regulating hepatic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4e846e48b3e395486746888e372063
https://doi.org/10.1016/j.jcmgh.2021.05.006
https://doi.org/10.1016/j.jcmgh.2021.05.006
Autor:
Chang Hwa Jung, Hyunjung Lee, Hyo-Deok Seo, Jiyun Ahn, Young In Kim, Tae-Youl Ha, Seung Yeon Ha
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1201-1213 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The development of nonalcoholic fatty liver disease (NAFLD) can be modulated by microRNAs (miRNA). Dietary polyphenols modulate the expression of miRNA such as miR-467b-3p in the liver. In addition, 6-gingerol (6-G), the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3294865d4fb01bb2374fab59ed3691
http://www.sciencedirect.com/science/article/pii/S2352345X21001223
http://www.sciencedirect.com/science/article/pii/S2352345X21001223
Autor:
Klaus Schughart, Diana Cabrera, Heike Kollmus, Carolin Pilzner, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez
Publikováno v:
The Journal of biological chemistry
United States
The Journal of Biological Chemistry
United States
The Journal of Biological Chemistry
Influenza A virus (IAV) infection casts a significant burden on society. It has particularly high morbidity and mortality rates in patients suffering from metabolic disorders. The aim of this study was to relate metabolic changes with IAV susceptibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35df79d0e1826add7a81f0ba6216551f
https://hdl.handle.net/10033/623093
https://hdl.handle.net/10033/623093
Autor:
Naoya Sakamoto, Koji Nakagawa, Goki Suda, Ayaka Asano, Masanobu Kobayashi, Mitsuteru Natsuizaka, Shunsuke Ohnishi, Hiroshi Takeda, Osamu Maehara
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 6, Pp 545-556 (2019)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 6, Pp 545-556 (2019)
CD133 is a cellular surface protein, which has been reported to be a cancer stem cell marker, and thus is considered a potential target for cancer treatment. Metformin, one of the biguanides used for the treatment of diabetes, is also known to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7622a72464a68bd5e5a7720bad47e569
https://doi.org/10.1016/j.neo.2019.03.007
https://doi.org/10.1016/j.neo.2019.03.007
Autor:
Ngoc Anh Hoang, Ina Bergheim, Helmut Sies, Lars-Oliver Klotz, Holger Steinbrenner, Mustafa Micoogullari
Publikováno v:
Redox Biology, Vol 20, Iss, Pp 489-495 (2019)
Redox Biology
Redox Biology
Selenium-binding protein 1 (SELENBP1) has recently been reported to catalyse the oxidation of methanethiol, an organosulfur compound produced by gut microbiota. Two of the reaction products of methanethiol oxidation, hydrogen peroxide and hydrogen su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dc29ec4b382eead239361950d6c410
https://doi.org/10.1016/j.redox.2018.11.004
https://doi.org/10.1016/j.redox.2018.11.004
Autor:
Yangyang Hu, Ting Yuan, Huan Chen, Ting Yang, Jing Wang, Hong Yu, Qing Yuan, Danli Fu, Xiang Xie, Wenfeng Xu
Publikováno v:
Redox Biology
Redox Biology, Vol 20, Iss, Pp 247-260 (2019)
Redox Biology, Vol 20, Iss, Pp 247-260 (2019)
Oxidative stress and inflammation interact in the development of diabetic atherosclerosis. Intracellular hyperglycemia promotes production of mitochondrial reactive oxygen species (ROS), increased formation of intracellular advanced glycation end-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9eba5d1c8ff637dfcb1b8003cebc6f
https://doi.org/10.1016/j.redox.2018.09.025
https://doi.org/10.1016/j.redox.2018.09.025
Autor:
Kendra K. Bence, William P. Esler
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
The prevalence and diagnosis of nonalcoholic fatty liver disease (NAFLD) is on the rise worldwide and currently has no FDA-approved pharmacotherapy. The increase in disease burden of NAFLD and a more severe form of this progressive liver disease, non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14a0440d3ac498ff260c68d959a6ab3
https://doi.org/10.1016/j.jcmgh.2019.04.007
https://doi.org/10.1016/j.jcmgh.2019.04.007
Autor:
Younes Achouri, Joseph P. Dewulf, Emile Van Schaftingen, Stéphanie Paquay, Etienne Marbaix, Guido T. Bommer
Publikováno v:
The Journal of Biological Chemistry
The Journal of biological chemistry, Vol. 297, no.4, p. 101083 (2021)
The Journal of biological chemistry, Vol. 297, no.4, p. 101083 (2021)
The cytosolic enzyme ethylmalonyl-CoA decarboxylase (ECHDC1) decarboxylates ethyl- or methyl-malonyl-CoA, two side-products of acetyl-CoA carboxylase. These CoA derivatives can be used to synthesize a subset of branched-chain fatty acids (FAs). We pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b97fc024070caa6e86136ac1563a523
https://pubmed.ncbi.nlm.nih.gov/34419447
https://pubmed.ncbi.nlm.nih.gov/34419447
Publikováno v:
JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
International audience; Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease worldwide. It is characterised by steatosis, liver inflammation, hepatocellular injury and progressive fibrosis. Several preclinical models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31673956635c337dc60791ff712432
https://pubmed.ncbi.nlm.nih.gov/34667947
https://pubmed.ncbi.nlm.nih.gov/34667947