Zobrazeno 1 - 10
of 33
pro vyhledávání: '"ACAT activity"'
Autor:
Fei Xu, Wei Gu, Cai Lu, Yun Zhang, Shengjin Liu, Haiying Liao, Qinan Wu, Jun Chen, Yuqing Shen, Ke Bao
Publikováno v:
International Journal of Biological Macromolecules. 158:1141-1162
We studied the lipid-regulating effect and molecular mechanism of the medical components of Alisma orientalis: alisol A, alisol B, 23-acetyl alisol C (23C) and the 3 (alisol A): 1(alisol B):1(23C) and 2(alisol A):2(alisol B):1(23C) mixtures designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ed6e4968558d0be5284d7e4a04691e
https://doi.org/10.1016/j.ijbiomac.2020.04.260
https://doi.org/10.1016/j.ijbiomac.2020.04.260
Publikováno v:
Аграрний вісник Причорномор'я.
За результатами досліджень інтенсивності інвазії демодекозу у хворих собак за генералізованої форми демодекозу встановлено,що на 10 - д
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74cffe236d07f797aff994723ef37390
https://doi.org/10.37000/abbsl.2021.99.16
https://doi.org/10.37000/abbsl.2021.99.16
Autor:
Therese M Heinonen
Publikováno v:
Expert Opinion on Investigational Drugs. 11:1519-1527
Cholesterol is an essential building block without which humans and other animals could not exist. As with most necessities, under certain conditions, excess can sharply tip the scale and lead to an unfavourable outcome. Excess cholesterol is stored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d29b1ff089b2c7dc6239def0e17d32
https://doi.org/10.1517/13543784.11.11.1519
https://doi.org/10.1517/13543784.11.11.1519
Autor:
Tsuyoshi Noguchi, Hiroshi Shimizu, Masami Muraoka, Katsuhisa Ioriya, Katsuya Fujita, Naohito Ohashi
Publikováno v:
Pharmacology. 65:18-25
We investigated the effects of SMP-500, a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on ACAT activities in the liver and intestine, and in macrophages. We measured its effects on the serum cholesterol levels and hepatic cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a03242825a20f889baf228169e6a499
https://doi.org/10.1159/000056181
https://doi.org/10.1159/000056181
Publikováno v:
Japanese Journal of Pharmacology. 76:309-312
We examined the inhibitory potency of F-1394 ((lS,2S)-2-[3-(2,2-dimethylpropyl)-3-nonylureido]cyclohexane-1-yl 3-[(4R)-N(2,2,5,5-tetramethyl-l,3-dioxane-4-carbonyl)amino]propionate), an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on ACAT a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b333a7af50b06dd62017c52ff530332
https://doi.org/10.1254/jjp.76.309
https://doi.org/10.1254/jjp.76.309
Autor:
Hart Terance William, Christopher Smith, Neil Victor Harris, David Riddell, R. Jordan, Ashton Michael John, Vincenzo Facchini, R.C. Bush, R. MacKenzie
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:47-50
RP 73163 5 the major metabolite of the ACAT inhibitor RP 76076 3 retains ACAT activity. This alkylsulphinyl-4,5-diphenyl-1H-imidazole has higher systemic bioavailability than the parent thioether, with plasma levels of parent compound in certain spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48126fcdfe0bcf10b7c686ec5d6b16c5
https://doi.org/10.1016/0960-894x(95)00555-8
https://doi.org/10.1016/0960-894x(95)00555-8
Autor:
Akira Nagayoshi, Masakuni Okuhara, Kazuhiko Ohne, Yoshikuni Ito, Yoshitada Notsu, Yuri Sakuma, Hiroyuki Hagihara, Seitaro Mutoh
Publikováno v:
Japanese Journal of Pharmacology. 70:35-41
FR129169 (FR) (N-(l,2-diphenylethyl)-2-octyloxyphenylacetamide) has been found to inhibit acyl-CoA:cholesterol acyltransferase (ACAT) activities in intestinal microsomes of rats and rabbits and the liver homogenate of rats with IC50 values of around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fc62abb47e4b1d1f042b45b36e6fcd
https://doi.org/10.1254/jjp.70.35
https://doi.org/10.1254/jjp.70.35
Autor:
Kazuro Shiomi, Hiroshi Tomoda, Noriko Tabata, Satoshi Omura, Noriko Arai, Rokuro Masuma, Da Jun Yang, Tomoya Kawakubo
Publikováno v:
The Journal of Antibiotics. 48:696-702
New azaphilones named isochromophilones III-VI were isolated from the culture broth of Penicillium multicolor FO-3216 as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT). Their structures were elucidated by NMR and other spectroscopic analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294af0e9eeb89162056f6da505535e36
https://doi.org/10.7164/antibiotics.48.696
https://doi.org/10.7164/antibiotics.48.696
Autor:
Oh Eok Kwon, Koanhoi Kim, Mun-Chual Rho, Seung Woong Lee, Hyun Sun Lee, Young-Kook Kim, Hye Young Song, Jin Ah Baek, Kyung Hee Jeune, Mi Yeon Chung
Publikováno v:
Archives of Pharmacal Research. 26:716-718
In the course of our search for Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors from natural sources, a new type of ACAT inhibitor was isolated from a methanol extract of Diospyros kaki. On the basis of spectral and structural evidence, the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf20f4eb045072c2cc9aa33ae531019d
https://doi.org/10.1007/bf02976679
https://doi.org/10.1007/bf02976679
Autor:
Yoshikazu Morishita, Katsuhiko Ando, Yuzuru Matsuda, Kazutoshi Kuroda, Yutaka Saito, Yoji Ikuina, Isao Kawamoto
Publikováno v:
ChemInform. 25
AS-186a, b, c, d, and g were isolated from the cultured broth of Penicillium asperosporum KY1635 as inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT). IC50 values for the effect of AS-186a, b, c, d, and g against ACAT activity of the microso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f159d240524697a73679cc806c9fd94
https://doi.org/10.1002/chin.199431281
https://doi.org/10.1002/chin.199431281