Zelluläre und subzelluläre Lokalisation von Angiopoietin-2 in der Lunge

Autor: B Gutbier, C Veith-Berger, J Berg, K Hellwig, M Mieth, AK Neuhauß, TT Bauer, M Tönnies, M Witzenrath, AC Hocke

Publikováno v: Pneumologie. 69

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::686b0e94ccf8c637d7f059603604d628
https://doi.org/10.1055/s-0035-1548662

Sphingosinkinase-1 und Sphingosin-1-Phosphat tragen zur Entstehung des akuten Lungenversagens bei Pneumokokken-Pneumonie

Autor: B Gutbier, SM Schönrock, R Haberberger, AC Hocke, S Hippenstiel, A Lüth, B Kleuser, WG Bertrams, K Szymanski, K Reppe, HC Müller, B Schmeck, M Andratsch, TJ Mitchell, H Schütte, K Mayer, N Suttorp, M Witzenrath

Publikováno v: Pneumologie. 65

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5547dd9423e413fed57f3cf3a411162
https://doi.org/10.1055/s-0031-1296110

Microenvironmental acidification by pneumococcal sugar consumption fosters barrier disruption and immune suppression in the human alveolus.

Autor: Fatykhova D; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Fritsch VN; Institute of Biology-Microbiology, Freie Universität Berlin, Berlin, Germany., Siebert K; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Methling K; University of Greifswald, Institute of Biochemistry, Metabolomics, Greifswald, Germany., Lalk M; University of Greifswald, Institute of Biochemistry, Metabolomics, Greifswald, Germany., Busche T; Center for Biotechnology, University Bielefeld, Bielefeld, Germany.; NGS Core Facility, Medical School OWL, Bielefeld University, Bielefeld, Germany., Kalinowski J; Center for Biotechnology, University Bielefeld, Bielefeld, Germany., Weiner J; Core Unit Bioinformatics, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Beule D; Core Unit Bioinformatics, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Bertrams W; Institute for Lung Research, Universities of Giessen and Marburg Lung Center, German Center for Lung Research (DZL), Philipps University Marburg, Marburg, Germany., Kohler TP; Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Germany., Hammerschmidt S; Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Germany., Löwa A; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Fischer M; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Mieth M; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Hellwig K; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Frey D; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Neudecker J; Department of General, Visceral, Vascular and Thoracic Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany., Rueckert JC; Department of General, Visceral, Vascular and Thoracic Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany., Toennies M; HELIOS Clinic Emil von Behring, Department of Pneumology and Department of Thoracic Surgery, Chest Hospital Heckeshorn, Berlin, Germany., Bauer TT; HELIOS Clinic Emil von Behring, Department of Pneumology and Department of Thoracic Surgery, Chest Hospital Heckeshorn, Berlin, Germany., Graff M; Department of Thoracic Surgery, DRK Clinics, Berlin, Germany., Tran HL; Department of Thoracic Surgery, Vivantes Clinics Neukölln, Berlin, Germany., Eggeling S; Department of Thoracic Surgery, Vivantes Clinics Neukölln, Berlin, Germany., Gruber AD; Department of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany., Antelmann H; Institute of Biology-Microbiology, Freie Universität Berlin, Berlin, Germany., Hippenstiel S; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Contributed equally., Hocke AC; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany andreas.hocke@charite.de.; Contributed equally.

Publikováno v: The European respiratory journal [Eur Respir J] 2024 Sep 04. Date of Electronic Publication: 2024 Sep 04.

Author Correction: Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins.

Autor: Aziz UBA; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany., Saoud A; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany., Bermudez M; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.; Institute for Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany., Mieth M; Department of Infectious Diseases, Respiratory Medicine, and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Atef A; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany.; Department of Medicinal Chemistry, Faculty of Pharmacy, Assuit University, Assiut, 71526, Egypt., Rudolf T; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany., Arkona C; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany., Trenkner T; Leibniz Institute of Virology, Hamburg, 20251, Germany., Böttcher C; Institute of Chemistry and Biochemistry, Research Center of Electron Microscopy (FZEM), Freie Universität Berlin, Fabeckstraße 36A, 14195, Berlin, Germany., Ludwig K; Institute of Chemistry and Biochemistry, Research Center of Electron Microscopy (FZEM), Freie Universität Berlin, Fabeckstraße 36A, 14195, Berlin, Germany., Hoelzemer A; Leibniz Institute of Virology, Hamburg, 20251, Germany.; First Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), 20251, Hamburg, Germany., Hocke AC; Department of Infectious Diseases, Respiratory Medicine, and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Wolber G; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany., Rademann J; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195, Berlin, Germany. joerg.rademann@fu-berlin.de.

Publikováno v: Nature communications [Nat Commun] 2024 May 21; Vol. 15 (1), pp. 4323. Date of Electronic Publication: 2024 May 21.

Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets.

Autor: Halwe NJ; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany., Hamberger L; Institute of Virology, Medical Center-University of Freiburg, 79104, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany., Sehl-Ewert J; Department of Experimental Animal Facilities and Biorisk Management, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany., Mache C; Unit 17, Influenza and Other Respiratory Viruses, Robert Koch-Institut, Seestraße 10, 13353, Berlin, Germany., Schön J; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany., Ulrich L; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany., Calvelage S; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany., Tönnies M; HELIOS Clinic Emil von Behring, Department of Pneumology and Department of Thoracic Surgery, Chest Hospital Heckeshorn, Berlin, Germany., Fuchs J; Institute of Virology, Medical Center-University of Freiburg, 79104, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany., Bandawane P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Loganathan M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Abbad A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Carreño JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bermúdez-González MC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kandeil A; Center of Scientific Excellence for Influenza Virus, Institute of Environmental Research and Climate Changes, National Research Centre, Giza, Egypt.; Human Link DMCC, Dubai, United Arab Emirates., El-Shesheny R; Center of Scientific Excellence for Influenza Virus, Institute of Environmental Research and Climate Changes, National Research Centre, Giza, Egypt.; Human Link DMCC, Dubai, United Arab Emirates., Ali MA; Center of Scientific Excellence for Influenza Virus, Institute of Environmental Research and Climate Changes, National Research Centre, Giza, Egypt., Kayali G; Center of Scientific Excellence for Influenza Virus, Institute of Environmental Research and Climate Changes, National Research Centre, Giza, Egypt.; Human Link DMCC, Dubai, United Arab Emirates., Budt M; Unit 17, Influenza and Other Respiratory Viruses, Robert Koch-Institut, Seestraße 10, 13353, Berlin, Germany., Hippenstiel S; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany., Hocke AC; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wolff T; Unit 17, Influenza and Other Respiratory Viruses, Robert Koch-Institut, Seestraße 10, 13353, Berlin, Germany., Schwemmle M; Institute of Virology, Medical Center-University of Freiburg, 79104, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany., Ciminski K; Institute of Virology, Medical Center-University of Freiburg, 79104, Freiburg, Germany. kevin.ciminski@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany. kevin.ciminski@uniklinik-freiburg.de., Hoffmann D; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany. donata.hoffmann@fli.de., Beer M; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493, Greifswald, Insel Riems, Germany. martin.beer@fli.de.

Publikováno v: Nature communications [Nat Commun] 2024 Apr 25; Vol. 15 (1), pp. 3450. Date of Electronic Publication: 2024 Apr 25.