Zobrazeno 1 - 10
of 16
pro vyhledávání: '"AC, adenylate cyclase"'
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3861-3876 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3861-3876 (2020)
Graphical abstract
Highlights • Toxoplasma genome harbors at least 18 phosphodiesterases encoded by distinct genes. • Most parasite PDEs lack regulatory modules and are quite divergent from their human orthologs. • Acutely-infectious tachy
Highlights • Toxoplasma genome harbors at least 18 phosphodiesterases encoded by distinct genes. • Most parasite PDEs lack regulatory modules and are quite divergent from their human orthologs. • Acutely-infectious tachy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952729672d93971172ad6bb332f7a8ef
http://europepmc.org/articles/PMC7720076
http://europepmc.org/articles/PMC7720076
Autor:
Hossam M. Abdallah, Gamal A. Mohamed, Ali M. El-Halawany, Martin K. Safo, Noura A. Hassan, Hany M. El-Bassossy
Publikováno v:
Journal of Advanced Research, Vol 24, Iss, Pp 273-279 (2020)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Highlights • Methanol extract of Psiadia punctulata (MAPP) produced a significant vasodilation. • Chloroform fraction and its methylated flavonoids were responsible for this effect. • Vasodilation is referred to endothel
Highlights • Methanol extract of Psiadia punctulata (MAPP) produced a significant vasodilation. • Chloroform fraction and its methylated flavonoids were responsible for this effect. • Vasodilation is referred to endothel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e154d40b7f6c70738bd46a118a460f
http://www.sciencedirect.com/science/article/pii/S2090123220300023
http://www.sciencedirect.com/science/article/pii/S2090123220300023
Autor:
Nadezhda Malysheva, Anja M. Richter, Regine Hengge, Alexandra Possling, Kaveh Pouran Yousef, Susanne Herbst, Max von Kleist
Publikováno v:
Journal of Molecular Biology
In many bacteria, the biofilm-promoting second messenger c-di-GMP is produced and degraded by multiple diguanylate cyclases (DGC) and phosphodiesterases (PDE), respectively. High target specificity of some of these enzymes has led to theoretical conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b9e826190327cca543a0aaafc340ff
http://europepmc.org/articles/PMC7397504
http://europepmc.org/articles/PMC7397504
Publikováno v:
Redox Biology
Redox Biology, Elsevier, 2017, 12, pp.18-34. ⟨10.1016/j.redox.2017.01.007⟩
Redox Biology, Vol 12, Iss, Pp 18-34 (2017)
Redox Biology, Elsevier, 2017, 12, pp.18-34. ⟨10.1016/j.redox.2017.01.007⟩
Redox Biology, Vol 12, Iss, Pp 18-34 (2017)
Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62a1d3f10ae17aeb4cf416d517cd170
https://hal.archives-ouvertes.fr/hal-02349886
https://hal.archives-ouvertes.fr/hal-02349886
Autor:
Margit S, Müller
Publikováno v:
Biochemical Society Transactions
Astrocytic glycogen degradation is an important factor in metabolic support of brain function, particularly during increased neuronal firing. In this context, glycogen is commonly thought of as a source for the provision of energy substrates, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::574b8da551473b09e825850c6073b885
https://pubmed.ncbi.nlm.nih.gov/25233408
https://pubmed.ncbi.nlm.nih.gov/25233408
Autor:
Roslin J, Adamson, Anthony, Watts
Publikováno v:
Febs Letters
Highlights • Little is known of the kinetics of interactions between GPCRs and their signalling partners. • NTS1 binds Gαi1 and Gαs with affinities of 15 ± 6 nM and 31 ± 18 nM (SE), respectively. • This SPR assay may be applicable to multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66683f26538e7f8c86820f20abd0ee53
https://pubmed.ncbi.nlm.nih.gov/25447525
https://pubmed.ncbi.nlm.nih.gov/25447525
Structures of soluble guanylate cyclase: implications for regulatory mechanisms and drug development
Autor:
Opher, Gileadi
Publikováno v:
Biochemical Society Transactions
Activation of cGMP synthesis leads to vasodilation, and is an important mechanism in clinical treatment of angina, heart failure, and severe peripheral and pulmonary hypertension. The nitric oxide-responsive sGC (soluble guanylate cyclase) has been t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7dee024935ed4f8da6f8f538439cb12a
https://pubmed.ncbi.nlm.nih.gov/24450636
https://pubmed.ncbi.nlm.nih.gov/24450636
Publikováno v:
Bioscience Reports, Vol 32, Iss 5 (2012)
Bioscience Reports
Bioscience Reports
The second messengers cAMP and cGMP mediate a multitude of physiological processes. In mammals, these cyclic nucleotides are formed by related Class III nucleotidyl cyclases, and both ACs (adenylate cyclases) and GCs (guanylate cyclases) comprise tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327488c6f46380a7b9dc2e98fae1a721
http://www.bioscirep.org/bsr/032/0491/bsr0320491.htm
http://www.bioscirep.org/bsr/032/0491/bsr0320491.htm
Autor:
Yossan‑Var Tan, James A. Waschek
Publikováno v:
ASN Neuro, Vol 3 (2011)
ASN NEURO
ASN NEURO
MS (multiple sclerosis) is a chronic autoimmune and neurodegenerative pathology of the CNS (central nervous system) affecting approx. 2.5 million people worldwide. Current and emerging DMDs (disease-modifying drugs) predominantly target the immune sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f748190b08c1d26b9f1f491e1886984
https://doaj.org/article/e64728eaced048cd929fc072750ee04b
https://doaj.org/article/e64728eaced048cd929fc072750ee04b
Akademický článek
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