SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease

Autor: Colarusso, Stefania, Ferrigno, Federica, Ponzi, Simona, Pavone, Francesca, Conte, Immacolata, Abate, Luigi, Beghetto, Elisa, Missineo, Antonino, Amaudrut, Jerome, Bresciani, Alberto, Paonessa, Giacomo, Tomei, Licia, Montalbetti, Christian, Bianchi, Elisabetta, Toniatti, Carlo, Ontoria, Jesus M.

Publikováno v: In Bioorganic & Medicinal Chemistry 1 March 2022 57

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Design, synthesis and biological activity of peptides and peptidomimetics as modulators the urotensinergic system

Autor: Abate, Luigi

In the humane, the urotensinergical system is involved in several pathological conditions, from cardiovascular disease at the neoplastic condition. The urotensinergical system is mediated by two cyclic peptides U-II and URP, these conserve the same c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______152::126e9fa0340149b1db8ccc6cc323d085
http://www.fedoa.unina.it/13121/

Adult Swyer-James-MacLeod syndrome: report of two cases and review of the literature.

Autor: Abate, Luigi¹ l.abate@usl7.toscana.it, Biagi, Paolo¹, Fabbrini, Domenico¹, Nardi, Piero²

Publikováno v: Italian Journal of Medicine. 2014, Vol. 8 Issue 2, p127-131. 5p.

Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides

Autor: Alfonso Carotenuto, Paolo Grieco, William D. Lubell, Rosa Bellavita, Ettore Novellino, Etienne Billard, Diego Brancaccio, Paola Santicioli, Ali Munaim Yousif, David Chatenet, Salvatore Di Maro, Terence E. Hébert, Roberta d'Emmanuele di Villa Bianca, Francesco Merlino, Luigi Abate, Luciana Marinelli

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (3), pp.1455-1467. ⟨10.1021/acs.jmedchem.8b01601⟩

International audience; In accordance with their common but also divergent physiological actions, human urotensin II (1) and urotensin II-related peptide (2) could stabilize specific urotensin II receptor (UTR) conformations, thereby activating diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390eb6c999713918817c28dfe5429a17
http://hdl.handle.net/11591/408767