Zobrazeno 1 - 10
of 11
pro vyhledávání: '"AAALAC, Association for Assessment and Accreditation of Laboratory Animal Care"'
Autor:
Maodo Malick Diop, Shim-mo Hayashi, Mark R. Bauter, Jan Demyttenaere, Sean V. Taylor, Christie L. Harman, Gerhard Krammer, Odete Mendes, Jürgen Schnabel, Maria Bastaki, Michel Aubanel, Vivian Lu, Thierry Cachet, A.M. Api, Kevin J. Renskers
Publikováno v:
Current Research in Toxicology
Current Research in Toxicology, Vol 2, Iss, Pp 192-201 (2021)
Current Research in Toxicology, Vol 2, Iss, Pp 192-201 (2021)
Graphical abstract
Highlights • GLP-compliant 90-day study on β-ionone epoxide following OECD guideline. • β-Ionone epoxide produces no adverse effects at doses up to 80 mg/kg bw/day in rats. • β-Ionone epoxide had no effect on reproduc
Highlights • GLP-compliant 90-day study on β-ionone epoxide following OECD guideline. • β-Ionone epoxide produces no adverse effects at doses up to 80 mg/kg bw/day in rats. • β-Ionone epoxide had no effect on reproduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a1734febce3f0eddc6953294b37beb
https://doi.org/10.1016/j.crtox.2021.05.001
https://doi.org/10.1016/j.crtox.2021.05.001
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 557-570 (2021)
Toxicology Reports, Vol 8, Iss, Pp 557-570 (2021)
Highlights • Four-week repeated-dose toxicity of intramuscular DSS was studied in minipigs. • DSS administration at ≥10 mg/kg/day causes toxicity and injection-site reaction. • The NOAEL of DSS after 4-week administration was 2 mg/kg/day in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b26ee397ae350858c363f15bad4a7b1
https://doi.org/10.1016/j.toxrep.2021.02.022
https://doi.org/10.1016/j.toxrep.2021.02.022
Autor:
Noel Dybdal, Jason Cordes, Nick Edmunds, Gemma Ward, Helen Prior, Aileen Milne, Brian M. Roche, Michael Gerhard Hoffmann, Pascal Champéroux, Stéphane Milano, Mike Engwall, Ken Meecham, Rick Nelson, Jean-Pierre Valentin, Eric Delpy, Anna Bottomley, Mike Foley, Robert Kaiser, Kathryn Chapman
Publikováno v:
Journal of Pharmacological and Toxicological Methods
Introduction The Safety Pharmacology Society (SPS) and National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs) conducted a survey and workshop in 2015 to define current industry practices relating to housing of non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30f4fae26b6268120ca6210c96d3958
Autor:
Joerg Neddens, Stefanie Flunkert, Birgit Hutter-Paier, Tina Loeffler, Estibaliz Santiago-Mujica, Roland Rabl
Publikováno v:
Heliyon
Heliyon, Vol 5, Iss 3, Pp e01293-(2019)
Heliyon, Vol 5, Iss 3, Pp e01293-(2019)
Niemann-Pick type C disease (NPC) is a fatal autosomal recessive disorder characterized by a defect in the intracellular transport of lipoproteins leading to the accumulation of lipids in diverse tissues. A visceral and neuronal phenotype mimicking h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99f39a7aa57c35ebff86b253a3ba1e9
https://doi.org/10.1016/j.heliyon.2019.e01293
https://doi.org/10.1016/j.heliyon.2019.e01293
Publikováno v:
Toxicology Reports
Highlights • The dietary safety of a unique microalgal structuring fat produced by a heterotrophic fermentation process was assessed. • The algal fat was non-mutagenic in Salmonella typhimurium and Escherichia coli tester strains at up to 5000 μ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::163735f33ab40e13c2a47414d04db806
https://pubmed.ncbi.nlm.nih.gov/28959530
https://pubmed.ncbi.nlm.nih.gov/28959530
Autor:
Kalinich JF; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, 4555 South Palmer Road, Bethesda, MD 20889-5648, USA., Vergara VB; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, 4555 South Palmer Road, Bethesda, MD 20889-5648, USA., Hoffman JF; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, 4555 South Palmer Road, Bethesda, MD 20889-5648, USA.
Publikováno v:
Current research in toxicology [Curr Res Toxicol] 2022 Jul 25; Vol. 3, pp. 100083. Date of Electronic Publication: 2022 Jul 25 (Print Publication: 2022).
Autor:
Dubey VK; Dabur Research Foundation, 22, Site IV, Sahibabad, Ghaziabad 201010, Uttar Pradesh, India.; Amity Institute of Pharmacy, Amity University Uttar Pradesh, Sector-125, Noida 201313, Uttar Pradesh, India., Madan S; Amity Institute of Pharmacy, Amity University Uttar Pradesh, Sector-125, Noida 201313, Uttar Pradesh, India., Rajput SK; Department of Pharmaceutical Sciences, Gurukula Kangri Vishwavidyalaya, Jagjeetpur, Haridwar 249404, Uttarakhand, India., Singh AT; Dabur Research Foundation, 22, Site IV, Sahibabad, Ghaziabad 201010, Uttar Pradesh, India., Jaggi M; Dabur Research Foundation, 22, Site IV, Sahibabad, Ghaziabad 201010, Uttar Pradesh, India., Mittal AK; Amity Institute of Pharmacy, Amity University Noida, Uttar Pradesh, 322230 India.
Publikováno v:
Current research in toxicology [Curr Res Toxicol] 2021 Oct 28; Vol. 3, pp. 100057. Date of Electronic Publication: 2021 Oct 28 (Print Publication: 2022).
Autor:
Lu V; International Organization of the Flavor Industry, 1101 17th Street NW, Suite 700, Washington, DC 20036, USA., Bastaki M; International Organization of the Flavor Industry, 1101 17th Street NW, Suite 700, Washington, DC 20036, USA., Api AM; Research Institute for Fragrance Materials, Inc., 50 Tice Blvd., Woodcliff Lake, NJ 07677, USA., Aubanel M; Kerry Flavours France, Zl du Plan BP 82067, 63 Avenue Jean Maubert, 06131 Grasse Cedex, France., Bauter M; Product Safety Labs, 2394 US Route 130, Dayton, NJ 08810, USA., Cachet T; International Organization of the Flavor Industry, Avenue des Arts 6, B-1210 Brussels, Belgium., Demyttenaere J; European Flavour Association, Avenue des Arts 6, B-1210 Brussels, Belgium., Diop MM; V. Mane Fils, 620 Route de Grasse, 06620 Le Bar-sur-Loup, France., Harman CL; Flavor and Extract Manufacturers Association, 1101 17th Street NW, Suite 700, Washington, DC 20036, USA., Hayashi SM; Japan Flavor and Fragrance Materials Association, Sankeinihonbashi Bldg. 6F, 4-7-1 Nihonbashi-Honcho, Chuo-ku, Tokyo, 103-0023, Japan., Krammer G; Symrise AG, Muhlenfeldstrasse 1, 37603 Holzminden, Germany., Mendes O; Product Safety Labs, 2394 US Route 130, Dayton, NJ 08810, USA., Renskers KJ; Takasago International Corporation, 4 Volvo Drive, PO Box 932, Rockleigh, NJ 07647, USA., Schnabel J; Givaudan International SA, Kemptpark 50, 8310 Kemptthal, Switzerland., Taylor SV; International Organization of the Flavor Industry, 1101 17th Street NW, Suite 700, Washington, DC 20036, USA.
Publikováno v:
Current research in toxicology [Curr Res Toxicol] 2021 May 18; Vol. 2, pp. 192-201. Date of Electronic Publication: 2021 May 18 (Print Publication: 2021).
Autor:
Kim HS; Animal Model Research Group, Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongup, Jeonbuk, 56212, Republic of Korea., Kang GH; Animal Model Research Group, Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongup, Jeonbuk, 56212, Republic of Korea., Yang MJ; Jeonbuk Pathology Research Group, Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongup, Jeonbuk, 56212, Republic of Korea., Ahn HJ; Jeonbuk Quality Assurance Unit, Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongup, Jeonbuk, 56212, Republic of Korea., Han SC; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongup, Jeonbuk, 56212, Republic of Korea., Hwang JH; Animal Model Research Group, Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongup, Jeonbuk, 56212, Republic of Korea.
Publikováno v:
Toxicology reports [Toxicol Rep] 2021 Feb 26; Vol. 8, pp. 557-570. Date of Electronic Publication: 2021 Feb 26 (Print Publication: 2021).
Autor:
Santiago-Mujica E; QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria., Flunkert S; QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria., Rabl R; QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria., Neddens J; QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria., Loeffler T; QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria., Hutter-Paier B; QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria.
Publikováno v:
Heliyon [Heliyon] 2019 Mar 14; Vol. 5 (3), pp. e01293. Date of Electronic Publication: 2019 Mar 14 (Print Publication: 2019).