Selective changes in expression of integrin α-subunits in the intestinal epithelial Caco-2 cells under conditions of hypoxia and microcirculation

Autor: VG Artyushenko, DV Maltseva, AA Poloznikov

Publikováno v: Bulletin of Russian State Medical University.

Intestinal epithelial cells are constantly exposed to physiologically hypoxic environment. The further reduction of tissue oxygen delivery may result in the intestinal epithelial cells function impairment, being a sign of active inflammation. The cul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a60af138b777536ba15ab7903b417035
https://doi.org/10.24075/brsmu.2020.078

Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs.

Autor: Gaisina IN; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago, IL, USA. Electronic address: igaysina@uic.edu., Hushpulian DM; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia., Gaisin AM; Integrated Molecular Structure Education and Research Center, Northwestern University, Evanston, IL, USA., Kazakov EH; Fordham University, Bronx, NY, USA., Ammal Kaidery N; Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC, USA; Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA., Ahuja M; Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC, USA; Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA; Department of Pharmaceutical Sciences, University of Buffalo, Buffalo, NY, USA., Poloznikov AA; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia., Gazaryan IG; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia; Department of Chemical Enzymology, M.V.Lomonosov Moscow State University, Moscow, Russia; Department of Chemistry and Physical Sciences, Pace University, Pleasantville, NY, USA., Thatcher GRJ; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ, USA., Thomas B; Darby Children's Research Institute, Medical University of South Carolina, Charleston, SC, USA; Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA; Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA; Department of Drug Discovery, Medical University of South Carolina, Charleston, SC, USA. Electronic address: thomasbo@musc.edu.

Publikováno v: Neurochemistry international [Neurochem Int] 2021 Oct; Vol. 149, pp. 105148. Date of Electronic Publication: 2021 Jul 27.

HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons.

Autor: Poloznikov AA; Faculty of Biology and Biotechnology, HSE University, Moscow, Russia., Nersisyan SA; Faculty of Biology and Biotechnology, HSE University, Moscow, Russia., Hushpulian DM; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.; School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia., Kazakov EH; Department of Anatomy and Cell Biology, New York Medical College, Valhalla, NY, United States., Tonevitsky AG; Faculty of Biology and Biotechnology, HSE University, Moscow, Russia., Kazakov SV; Department of Chemistry and Physical Sciences, Dyson College of Arts and Sciences, Pace University, Pleasantville, NY, United States., Vechorko VI; City Clinical Hospital No 15 Named After O. M. Filatov, Moscow, Russia., Nikulin SV; Faculty of Biology and Biotechnology, HSE University, Moscow, Russia., Makarova JA; Faculty of Biology and Biotechnology, HSE University, Moscow, Russia., Gazaryan IG; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.; Department of Anatomy and Cell Biology, New York Medical College, Valhalla, NY, United States.; Department of Chemistry and Physical Sciences, Dyson College of Arts and Sciences, Pace University, Pleasantville, NY, United States.; Chemical Enzymology Department, M. V. Lomonosov Moscow State University, Moscow, Russia.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2021 Jan 29; Vol. 11, pp. 621054. Date of Electronic Publication: 2021 Jan 29 (Print Publication: 2020).

Breast cancer organoid model allowed to reveal potentially beneficial combinations of 3,3'-diindolylmethane and chemotherapy drugs.

Autor: Nikulin SV; Faculty of Biology and Biotechnologies, Higher School of Economics, Moscow, 101000, Russia; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Alekseev BY; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Sergeeva NS; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Karalkin PA; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Nezhurina EK; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Kirsanova VA; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Sviridova IK; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Akhmedova SA; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Volchenko NN; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Bolotina LV; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia., Osipyants AI; School of Biomedicine, Far Eastern Federal University, Vladivostok, 690091, Russia., Hushpulian DM; School of Biomedicine, Far Eastern Federal University, Vladivostok, 690091, Russia; Institute of Nanotechnology of Microelectronics, 32A Leninsky Prospekt, Moscow, 119991, Russia., Topchiy MA; A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow, 119991, Russia., Asachenko AF; A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov str. 28, Moscow, 119991, Russia., Koval AP; Molecular Oncology Laboratory, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, 117997, Russia., Shcherbo DS; Molecular Oncology Laboratory, Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow, 117997, Russia., Kiselev VI; National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Moscow, 117997, Russia., Mikhaylenko DS; Institute of Molecular Medicine, Biomedical Science and Technology Park, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, 119991, Russia; Research Centre for Medical Genetics, Moscow, 115522, Russia., Schumacher U; Institute of Anatomy and Experimental Morphology, University Medical Center, Hamburg-Eppendorf, Hamburg, 20246, Germany., Poloznikov AA; Faculty of Biology and Biotechnologies, Higher School of Economics, Moscow, 101000, Russia; P. A. Hertsen Moscow Oncology Research Center, Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, 125284, Russia. Electronic address: apoloznikov@hse.ru.

Publikováno v: Biochimie [Biochimie] 2020 Dec; Vol. 179, pp. 217-227. Date of Electronic Publication: 2020 Oct 22.

miRNAs expression signature potentially associated with lymphatic dissemination in locally advanced prostate cancer.

Autor: Pudova EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. rhizamoeba@mail.ru., Krasnov GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Nyushko KM; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia., Kobelyatskaya AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Savvateeva MV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Poloznikov AA; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia., Dolotkazin DR; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia., Klimina KM; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia., Guvatova ZG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Simanovsky SA; A. N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, Russia., Gladysh NS; MSAVM&B - MVA named after K.I. Skryabin, Moscow, Russia., Tokarev AT; MSAVM&B - MVA named after K.I. Skryabin, Moscow, Russia., Melnikova NV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Dmitriev AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Alekseev BY; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia., Kaprin AD; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia., Kiseleva MV; National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia., Snezhkina AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia., Kudryavtseva AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

Publikováno v: BMC medical genomics [BMC Med Genomics] 2020 Sep 18; Vol. 13 (Suppl 8), pp. 129. Date of Electronic Publication: 2020 Sep 18.