Zobrazeno 1 - 10
of 94
pro vyhledávání: '"AA Melcher"'
Autor:
MJ Melake, HG Smith, D Mansfield, E Davies, MT Dillon, AC Wilkins, EC Patin, M Pedersen, R Buus, AA Melcher, K Thway, AB Miah, SH Zaidi, AJ Hayes, TR Fenton, KJ Harrington, M McLaughlin
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Systemic relapse after radiotherapy and surgery is the major cause of disease-related mortality in sarcoma patients. Combining radiotherapy and immunotherapy is under investigation as a means to improve response rates. However, the immune contexture
Externí odkaz:
https://doaj.org/article/81afcd7101924da99decc87c750acf06
Autor:
Michael Gough, Aa, Melcher, Ahmed A, Crittenden MR, Ds, Riddle, Linardakis E, An, Ruchatz, Lm, Emiliusen, Rg, Vile
Publikováno v:
Europe PubMed Central
The mechanisms by which the immune system distinguishes normal developmental cell death from pathological immunogenic cell killing are central to effective cancer immunotherapy. Using HSVtk suicide gene therapy, we showed that macrophages can disting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::30e3fee50d634b1fafa7fc4cb541be3b
https://pubmed.ncbi.nlm.nih.gov/11585761
https://pubmed.ncbi.nlm.nih.gov/11585761
Publikováno v:
British Journal of Cancer
High response rates have been reported in the treatment of advanced gastric cancer with epirubicin, cisplatin and continuous infusion 5-fluorouracil (ECF), including instances of unresectable disease being rendered operable by chemotherapy. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac3f7b542f2c5908936e6ee53d57de1
https://pubmed.ncbi.nlm.nih.gov/8932350
https://pubmed.ncbi.nlm.nih.gov/8932350
CXCL12-targeted immunomodulatory gene therapy reduces radiation-induced fibrosis in healthy tissues.
Autor:
Paget JT; Institute of Cancer Research, London, United Kingdom., Ward JA; Institute of Cancer Research, London, United Kingdom., McKean AR; Institute of Cancer Research, London, United Kingdom., Mansfield DC; Institute of Cancer Research, London, United Kingdom., McLaughlin M; Institute of Cancer Research, London, United Kingdom., Kyula-Currie JN; Institute of Cancer Research, London, United Kingdom., Smith HG; Copenhagen University Hospital, Copenhagen, Denmark., Roulstone V; Institute of Cancer Research, London, United Kingdom., Li C; Cardiff University, Cardiff, United Kingdom., Zhou Y; Cardiff University, Cardiff, United Kingdom., Hardiman T; King's College London, United Kingdom., Grigoriadis A; King's College London, London, United Kingdom., O'Brien Coon D; Brigham and Women's Faulkner Hospital, Boston, United States., Irshad S; King's College London, London, United Kingdom., Melcher AA; Institute of Cancer Research, London, United Kingdom., Harrington KJ; Institute of Cancer Research, London, United Kingdom., Khan A; Institute of Cancer Research, London, United Kingdom.
Publikováno v:
Molecular cancer therapeutics [Mol Cancer Ther] 2024 Dec 12. Date of Electronic Publication: 2024 Dec 12.
Autor:
Patin EC; Targeted Therapy Team, The Institute of Cancer Research, London, UK. emmanuel.patin@icr.ac.uk., Nenclares P; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Chan Wah Hak C; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Dillon MT; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Patrikeev A; Targeted Therapy Team, The Institute of Cancer Research, London, UK., McLaughlin M; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Grove L; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Foo S; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Soliman H; The Royal Marsden Hospital, London, UK., Barata JP; The Royal Marsden Hospital, London, UK., Marsden J; The Royal Marsden Hospital, London, UK., Baldock H; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Gkantalis J; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Roulstone V; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Kyula J; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Burley A; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Hubbard L; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Pedersen M; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Smith SA; Early Oncology R&D, AstraZeneca, Cambridge, UK., Clancy-Thompson E; Early Oncology R&D, AstraZeneca, Cambridge, UK., Melcher AA; Translational Immunotherapy Team, The Institute of Cancer Research, London, UK., Ono M; Department of Life Sciences, Imperial College London, London, UK., Rullan A; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Harrington KJ; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK.
Publikováno v:
Nature communications [Nat Commun] 2024 Aug 13; Vol. 15 (1), pp. 6923. Date of Electronic Publication: 2024 Aug 13.
Autor:
Wongariyapak A; Targeted Therapy Team, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK., Roulstone V; Targeted Therapy Team, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK., Melcher AA; Translational Immunotherapy Team, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK., Pedersen M; Targeted Therapy Team, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK.; Translational Immunotherapy Team, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK., Harrington KJ; Targeted Therapy Team, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK.
Publikováno v:
Annals of translational medicine [Ann Transl Med] 2023 Aug 30; Vol. 11 (10), pp. 369. Date of Electronic Publication: 2023 Mar 17.
Autor:
Chan Wah Hak CML; Translational Immunotherapy Team, The Institute of Cancer Research, London, United Kingdom., Rullan A; Targeted Therapy Team, The Institute of Cancer Research, London, United Kingdom., Patin EC; Targeted Therapy Team, The Institute of Cancer Research, London, United Kingdom., Pedersen M; Targeted Therapy Team, The Institute of Cancer Research, London, United Kingdom., Melcher AA; Translational Immunotherapy Team, The Institute of Cancer Research, London, United Kingdom., Harrington KJ; Targeted Therapy Team, The Institute of Cancer Research, London, United Kingdom.
Publikováno v:
Frontiers in oncology [Front Oncol] 2022 Aug 29; Vol. 12, pp. 971959. Date of Electronic Publication: 2022 Aug 29 (Print Publication: 2022).
Autor:
Samson A; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., West EJ; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Carmichael J; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Scott KJ; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Turnbull S; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Kuszlewicz B; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Dave RV; Manchester University NHS Foundation Trust, Manchester, United Kingdom., Peckham-Cooper A; Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., Tidswell E; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Kingston J; Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., Johnpulle M; Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., da Silva B; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Jennings VA; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Bendjama K; Transgene, Strasbourg, France., Stojkowitz N; Transgene, Strasbourg, France., Lusky M; Transgene, Strasbourg, France., Prasad KR; Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., Toogood GJ; Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., Auer R; Ontario Health Research Institute, Ottawa, Canada., Bell J; Ontario Health Research Institute, Ottawa, Canada., Twelves CJ; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Harrington KJ; The Institute of Cancer Research, London, United Kingdom., Vile RG; Mayo Clinic, Rochester, Minnesota., Pandha H; University of Surrey, Guildford, United Kingdom., Errington-Mais F; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Ralph C; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Newton DJ; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Anthoney A; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom., Melcher AA; The Institute of Cancer Research, London, United Kingdom., Collinson F; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom.
Publikováno v:
Cancer immunology research [Cancer Immunol Res] 2022 Jun 03; Vol. 10 (6), pp. 745-756.
Autor:
Melake MJ; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Smith HG; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; Digestive Disease Center, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Denmark., Mansfield D; Translational Immunotherapy Team, The Institute of Cancer Research, London, UK., Davies E; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Dillon MT; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Wilkins AC; The Royal Marsden Hospital, London, UK., Patin EC; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Pedersen M; Translational Immunotherapy Team, The Institute of Cancer Research, London, UK., Buus R; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Melcher AA; Translational Immunotherapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., Thway K; The Royal Marsden Hospital, London, UK., Miah AB; The Royal Marsden Hospital, London, UK., Zaidi SH; The Royal Marsden Hospital, London, UK., Hayes AJ; The Royal Marsden Hospital, London, UK., Fenton TR; University of Southampton, Somers Cancer Research Building MP824, Southampton General Hospital, Southampton, UK., Harrington KJ; Targeted Therapy Team, The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, London, UK., McLaughlin M; Targeted Therapy Team, The Institute of Cancer Research, London, UK.
Publikováno v:
Oncoimmunology [Oncoimmunology] 2022 May 09; Vol. 11 (1), pp. 2066050. Date of Electronic Publication: 2022 May 09 (Print Publication: 2022).
Autor:
Wantoch M; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Wilson EB; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Droop AP; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Phillips SL; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Coffey M; Oncolytics Biotech Inc, Calgary, Alberta, Canada., El-Sherbiny YM; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Holmes TD; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Melcher AA; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Wetherill LF; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK., Cook GP; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK.
Publikováno v:
Immunology [Immunology] 2022 May; Vol. 166 (1), pp. 104-120. Date of Electronic Publication: 2022 Mar 09.