Zobrazeno 1 - 10
of 141
pro vyhledávání: '"A.V. Powles"'
Autor:
Brian Kirby, Luisa W. Hugerth, L. Fry, Cheryl M. Sweeney, Anne-Marie Tobin, Stefanie Prast-Nielsen, Lars Engstrand, A.V. Powles, K. Adamzik
Publikováno v:
British Journal of Dermatology. 181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2eeaa7810749a923725e5cdf6c414c
https://doi.org/10.1111/bjd.18279
https://doi.org/10.1111/bjd.18279
Autor:
K. Adamzik, A.V. Powles, L. Fry, Lars Engstrand, Stefanie Prast-Nielsen, Brian Kirby, Cheryl M. Sweeney, Luisa W. Hugerth, Anne-Marie Tobin
Publikováno v:
The British journal of dermatologyReferences. 181(3)
Background Human skin is populated by diverse bacteria and there is increasing evidence that resident bacteria play a key role initiating immune responses in cutaneous diseases such as atopic dermatitis, psoriasis and hidradenitis suppurativa. Bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5797b471fac3c001eb723994f33dd7c
https://pubmed.ncbi.nlm.nih.gov/31353448
https://pubmed.ncbi.nlm.nih.gov/31353448
Publikováno v:
Experimental Dermatology. 24:241-244
The concept that psoriasis is an autoimmune disease needs to be questioned. The autoimmune label has been based on molecular mimicry between streptococcal and keratin proteins and the existence of homologous peptides between these proteins. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fa300a090feb366ac0964ed6c9c590
https://doi.org/10.1111/exd.12572
https://doi.org/10.1111/exd.12572
Autor:
Deborah A. Matthews, Elizabeth M. C. Fisher, Mark I. McCarthy, Robert Williamson, A.V. Powles, James L. Weber, Kay E. Davies, Lionel Fry
Psoriasis is an inflammatory skin disease that affects 2% of the population. It is characterised by red, scaly skin patches which are usually found on the scalp, elbows and knees, and may be associated with severe arthropathy. The lesions are caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71f915098bcc5f3fc188955b5a14ba4
https://doi.org/10.1038/ng1096-231
https://doi.org/10.1038/ng1096-231
Autor:
James R.C. Parkinson, Sarah Rogers, Damian Smedley, Lionel Fry, Ann Caird, Celine Charon, Stephanie Halford, B. S. Baker, A.V. Powles, Mark I. McCarthy
Evidence, largely from Irish pedigrees, indicates that a susceptibility locus for psoriasis maps to chromosome 4q. The gene encoding interferon regulatory factor-2 ( IRF-2 ) maps to this region, and, as mice lacking IRF-2 exhibit a dermatologic pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6c2f7b50d9f20d951609e69d6c52c6
https://doi.org/10.1046/j.0022-202x.2004.22135.x
https://doi.org/10.1046/j.0022-202x.2004.22135.x
Publikováno v:
British Journal of Dermatology. 167:980-986
Post-streptococcal guttate psoriasis only sometimes progresses to the persistent plaque psoriasis. We have previously proposed that psoriasis is driven by multiple extradomain A+ fibronectin (EDA+ FN) 'feedback loops'. The psoriasis-specific loop, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22807f1bdb90da82bed74697a09c02f
https://doi.org/10.1111/j.1365-2133.2012.11149.x
https://doi.org/10.1111/j.1365-2133.2012.11149.x
Publikováno v:
Archives of Dermatological Research. 302:495-498
Evidence exists that microorganisms, particularly in the throat and skin, play a role in the pathogenesis of psoriasis. The aim of this study was to investigate whether evidence for the presence of bacteria, including Streptococcus pyogenes, can be d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bdbbe95bed95da0623594a71ea8dbe7
https://doi.org/10.1007/s00403-010-1065-0
https://doi.org/10.1007/s00403-010-1065-0
Publikováno v:
British Journal of Dermatology. 163:5-11
We have previously postulated that as well as T-helper (Th) 1 and Th17 cells, the transforming growth factor (TGF)-beta/fibronectin (FN)/alpha5beta1 pathway is central to psoriasis pathogenesis. EDA+ FN refers to an alternatively spliced isoform of F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e255117cf5737c0e13c07ba5f1e8a2ef
https://doi.org/10.1111/j.1365-2133.2010.09737.x
https://doi.org/10.1111/j.1365-2133.2010.09737.x
Publikováno v:
British Journal of Dermatology. 160:929-937
We have previously postulated that surviving invasive streptococcal infections may have been a factor in psoriasis becoming a common skin disease in some parts of the world. Many of the candidate genes linked to psoriasis are associated with the acqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39971e7e1961357c2a39416f20f63ea3
https://doi.org/10.1111/j.1365-2133.2009.09102.x
https://doi.org/10.1111/j.1365-2133.2009.09102.x
Autor:
Marco Zucchelli, A.V. Powles, Lena Samuelsson, Ulpu Saarialho-Kere, Juha Kere, Sari Suomela, Kati Kainu, B. S. Baker, Annica Inerot, L. Fry, Katja Kivinen
Publikováno v:
Experimental Dermatology. 18:109-115
A susceptibility locus for psoriasis, PSORS4, has been mapped to chromosome 1q21 in the region of the epidermal differentiation complex. The region has been refined to a 115 kb interval around the loricrin (LOR) gene. However, no evidence of associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed817c35477ea7b545d8bea37fe0f8c9
https://doi.org/10.1111/j.1600-0625.2008.00769.x
https://doi.org/10.1111/j.1600-0625.2008.00769.x