Zobrazeno 1 - 10
of 81
pro vyhledávání: '"A.S. Hamblin"'
Publikováno v:
Veterinary Immunology and Immunopathology. 98:153-165
Lymphocytes play an important role in allergic inflammation and have been implicated in the pathogenesis of equine allergic skin and respiratory disease. Targeting intracellular signalling pathways in human lymphocytes has demonstrated a role for bot
Publikováno v:
Veterinary Immunology and Immunopathology. 87:215-221
Dendritic cells (DCs) are antigen presenting cells that potently modulate immune responses with varying outcomes depending on the DC sub-population involved. To understand how DC sub-types arise, it is necessary to determine which factors influence t
Publikováno v:
Clinical and Experimental Immunology. 129:281-287
SUMMARY Antisera to activated equine endothelial cells, which detected surface molecules of 116 kD, 97 kD, 42 kD and 38 kD, were made to investigate the role of endothelial adhesion molecules in equid herpes virus 1 infection. These putative adhesion
Publikováno v:
Research in Veterinary Science. 70:115-122
Intradermal injection of a Culicoides antigen extract (CAgX) induces T lymphocyte and eosinophil accumulation in the skin of horses with sweet itch. Blood mononuclear ( BMN ) cells from normal ponies proliferate when stimulated by mitogen (phytohaema
Publikováno v:
Journal of Comparative Pathology. 124:83-87
The number of antibodies for identifying equine B cells is small and the number that react with well-defined epitopes even smaller. The monoclonal antibody, BU33, which is directed against human CD21 (Complement Receptor 2; CR2) was shown to identify
Publikováno v:
Journal of Comparative Pathology. 122:145-154
Monoclonal antibodies (mAbs) recognizing equine macrophages are scarce. The present study compared the immunocytochemical staining of various equine tissues (lymphoid tissue, lung, liver, small intestine, skin and blood leucocytes) by an antibody, Ki
Publikováno v:
Veterinary Immunology and Immunopathology. 60:15-31
Despite their important role in initiating T-cell responses in other species, dendritic cells have not been studied in the horse. A method for isolating blood dendritic cells by adherence and metrizamide gradients was adapted to equine cells. A numbe
Publikováno v:
Cytokine. 19(1)
The chemokine eotaxin (CCL11) is a key player in the trafficking of eosinophils to normal tissues and in the tissue eosinophilia associated with human allergic disease. We have recently cloned equine eotaxin and here we report the production of rEq e
Publikováno v:
Autoimmunity. 35(2)
Lewis rats develop immune-mediated arthritis following injection with a variety of agents including bovine type II collagen (bCII), mycobacteria, muramyl dipeptide and CP20961. Since susceptibility to experimentally-induced arthritis has been linked
Publikováno v:
Journal of autoimmunity. 17(3)
Collagen-induced arthritis (CIA) is a T cell-dependent disease induced in susceptible rodents by immunizing with bovine type II collagen (bCII). In order to study T cell responses, a programme to generate bCII-specific T cell lines from arthritic rat