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pro vyhledávání: '"A.P. Wehner"'
Autor:
A.P. Wehner
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 32(12)
A review of the literature reveals two primary issues: (1) a weak, but not causal, association of hygienic use of cosmetic talc and ovarian cancer; (2) lung changes in animals exposed to talc aerosol concentrations that resulted in lung overload. The
Publikováno v:
Food and Cosmetics Toxicology. 15:589-593
When neutron-activated talc was suspended in bovine serum, 0·5% of the 60 Co and 3·1% of the 46 Sc occurring in the sample was found in the supernatant of the centrifuged and filtered suspension. A maximum of about 0·5% of each radionuclide can be
Autor:
A.P. Wehner
Publikováno v:
Chest. 60:468-471
Four-month-old female albino rats received a single 15 to 20 minute “nose-only” exposure to 239 PuO 2 dust (CMD 0.3μm). The animals were then randomly divided into experimental and control groups of 10, 12 and 18 rats each for three exploratory
Publikováno v:
Food and Cosmetics Toxicology. 15:453-455
Summary To determine talc absorption in the gastro-intestinal tract of hamsters, talc was neutron-activated and suspended in physiological saline and 1-ml aliquots of this suspension were administered by gastric intubation to six 10-wk-old Syrian gol
Publikováno v:
Food and cosmetics toxicology. 15(2)
Groups of 50 male and 50 female Syrian golden hamsters were exposed to talc aerosol for 3, 30 or 150min/day, 5 days/wk for 30 days, or for 30 or 150min/day either until they died naturally or for a maximum of 300 days. The mean concentration of the
Publikováno v:
Food and cosmetics toxicology. 15(3)
To determine pulmonary deposition, translocation and clearance of inhaled talc, 10-wk-old hamsters received a single 2-hr nose-only exposure to neutron-activated talc. Over a period of 4 months, the hamsters were killed in groups of four. Lungs, live
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 23(3)
To investigate whether particles deposited in the vagina translocate to the oviducts, 0.3 ml of a 4% bone black suspension was deposited in the posterior vaginal fornix of each of five cynomolgus monkeys (Macaca fascicularis) during their mid-menstru
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 24(4)
The objective of this study was to investigate whether multiple vaginal depositions of neutron-activated talc in the cynomolgus monkey result in the translocation of this material to the uterus and beyond. Within a 45-day period, six monkeys received
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