11b Prevention of postpartum haemorrhage

Autor: A.N.J.A. de Groot

Publikováno v: Baillière's Clinical Obstetrics and Gynaecology. 9:619-631

Primary prevention of PPH is advocated at all levels of obstetric care. This implies active management of the third stage of labour also at the first and most peripheral levels of obstetric care. Active management includes the use of an oxytocic, ear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ecb91440c86d4ab86b8670d8f531410
https://doi.org/10.1016/s0950-3552(05)80385-2

Oral administration of methylergometrine shows a late and unpredictable effect on the non-pregnant human menstruating uterus

Autor: Tom B. Vree, A.N.J.A. de Groot, P.W.J. van Dongen, Tom K.A.B. Eskes

Publikováno v: European Journal of Obstetrics & Gynecology and Reproductive Biology, 60, 101-107
European Journal of Obstetrics & Gynecology and Reproductive Biology, 60, pp. 101-107
European Journal of Obstetrics & Gynecology and Reproductive Biology, 60, 2, pp. 101-107

Objective: To study the pharmacodynamic and pharmacokinetic properties of oral and intravenous methylergometrine upon uterine motility during menstruation. Study-design: Intra-uterine pressure was measured in six volunteers with a fluid-filled sponge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ae5b9474dbb1b710f51b7eec0309a8
https://hdl.handle.net/2066/20775

Variation in Bioavailability of Oral Methylergometrine in Healthy Male Volunteers

Autor: A.N.J.A. de Groot, Tom B. Vree, Yechiel A. Hekster, J. van Roosmalen, M. van den Biggelaar-Martea, P.W.J. van Dongen

Publikováno v: Drug Investigation. 8:345-351

The aim of this investigation was to assess the pharmacokinetics and bioavail-ability of methylergometrine in 6 healthy male volunteers after an oral dose of 0.125mg and after an intravenous dose of 0.200mg. A large variation in bio-availability of b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48e95a4d0f29d1edb848043dae0d5410
https://doi.org/10.1007/bf03257449

The number of multinucleated trophoblastic giant cells in the basal decidua is decreased in retained placenta

Autor: Irma Joosten, Fred K. Lotgering, Johan Bulten, H. J. van Beekhuizen, A.N.J.A. de Groot, J.A.W.M. van der Laak

Publikováno v: Journal of Clinical Pathology, 62(9), 794-797. BMJ Publishing Group
Journal of Clinical Pathology : the Journal of the Association of Clinical Pathologists, 62, 9, pp. 794-7
Journal of Clinical Pathology : the Journal of the Association of Clinical Pathologists, 62, 794-7

Contains fulltext : 81223.pdf (Publisher’s version ) (Open Access) AIMS: Retained placenta (RP) is a major cause of obstetric haemorrhage. The aim of the study was to obtain a better understanding of the mechanisms that cause some placentas to beco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be9c1324bda226fea19ccd05f9533fa
https://doi.org/10.1136/jcp.2009.065953

History and use of oxytocics

Autor: P.W.J. van Dongen, C.E.C. den Hertog, A.N.J.A. de Groot

Publikováno v: European journal of obstetrics, gynecology, and reproductive biology. 94(1)

The most widely known oxytocic drug that can be used for the induction of labor or post-partum is oxytocin. In 1954, the american biochemist Vincent du Vigneaud was the first to describe an octapeptide amide with the hormonal activity of oxytocin. On

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44141edd526a7b782d27b3bdd09bb410
https://pubmed.ncbi.nlm.nih.gov/11134819