Zobrazeno 1 - 10
of 15
pro vyhledávání: '"A.M. Bouwman"'
Publikováno v:
Cell Reports, Vol 29, Iss 3, Pp 560-572.e4 (2019)
Summary: DNA double-strand breaks (DSBs) are deleterious and tumorigenic but could also be essential for DNA-based processes. Yet the landscape of physiological DSBs and their role and repair are still elusive. Here, we mapped DSBs at high resolution
Externí odkaz:
https://doaj.org/article/8491ff4ff89747c1a2808ac7bb50c69e
Publikováno v:
Current Opinion in Cell Biology. 74:7-12
A growing body of evidence points to a role of nuclear RNAs (nucRNAs) in shaping the three-dimensional (3D) architecture of the genome within the nucleus of a eukaryotic cell. nucRNAs are non-homogeneously distributed within the nucleus where they ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f96fa1b1a539ef5c4cfb5034e20d7
https://doi.org/10.1016/j.ceb.2021.12.001
https://doi.org/10.1016/j.ceb.2021.12.001
Publikováno v:
Trends in genetics : TIG. 38(10)
Over a decade ago the advent of high-throughput chromosome conformation capture (Hi-C) sparked a new era of 3D genomics. Since then the number of methods for mapping the 3D genome has flourished, enabling an ever-increasing understanding of how DNA i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6024d3d5f53d4a0a9d99e8ab2c13b9
https://pubmed.ncbi.nlm.nih.gov/35680466
https://pubmed.ncbi.nlm.nih.gov/35680466
Autor:
Carlo Vermeulen, Amin Allahyar, Britta A.M. Bouwman, Peter H.L. Krijger, Marjon J.A.M. Verstegen, Geert Geeven, Christian Valdes-Quezada, Ivo Renkens, Roy Straver, Wigard P. Kloosterman, Jeroen de Ridder, Wouter de Laat
We present the protocol and data analysis toolbox for Multi-Contact 4C (MC-4C), a new proximity ligation method tailored to study the higher-order chromatin contact patterns of selected genomic sites. Conventional chromosome conformation capture (3C)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc4f545c71cd2ee9f5aed8ce124dcf77
https://doi.org/10.17504/protocols.io.zmwf47e
https://doi.org/10.17504/protocols.io.zmwf47e
Publikováno v:
International Journal of Pharmaceutics, 318(1-2), 78-85. Elsevier Bedrijfsinformatie b.v.
The objective of this study was three-fold; to investigate the different mechanisms of material exchange during the equilibrium phase of the granulation process and whether these mechanisms are consistent with the mechanisms described in the growth r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5f799a619cc52c04737a2a13527d36
https://doi.org/10.1016/j.ijpharm.2006.03.038
https://doi.org/10.1016/j.ijpharm.2006.03.038
Autor:
E.J. Duiverman, A.M. Bouwman, P. N. LeSouef, N. C. Schaefer, M.P. Heijstra, Sunalene G. Devadason
Publikováno v:
Drug Delivery, 13(5), 357-363. Taylor & Francis Group
Our aim was to improve the efficiency of nebulised budesonide using surface-active agents. Cationic, anionic, and nonionic detergents were added to commercial budesonide suspension, and the particle size distribution during nebulization was measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ec6a7c6dbf936125883af2d6c5c3f3
https://doi.org/10.1080/10717540500458862
https://doi.org/10.1080/10717540500458862
Autor:
Zhibing Zhang, D. Westerman, J.T. Chung, M.J. Henstra, A.M. Bouwman, Andrew Ingram, Henderik W. Frijlink, J.P.K. Seville
Publikováno v:
International Journal of Pharmaceutics, 290(1-2), 129-136. Elsevier Bedrijfsinformatie b.v.
The structure of granules changes during the high shear granulation process. The purpose of this research was to investigate the effect of the amount of binder liquid on the structure of the granules and the structural changes which occur during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981f9d7468883786d5e04707442d5270
https://research.rug.nl/en/publications/512ceab5-d469-4478-a312-5b7fd39c9455
https://research.rug.nl/en/publications/512ceab5-d469-4478-a312-5b7fd39c9455
Autor:
M.J. Henstra, A.M. Bouwman, Henderik W. Frijlink, J.P.K. Seville, J.J.M.E. Hegge, Andrew Ingram, Zhibing Zhang
Publikováno v:
Pharmaceutical Research, 22(2), 270-275. SPRINGER/PLENUM PUBLISHERS
Purpose. To investigate the background of the observed relationship between measured torque and granule size in high-shear granulation processes.Methods. Torque was measured during the granulation process; the behavior of individual wet granules duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490b07807d5ef24a21d0b26aba4ad5c4
https://hdl.handle.net/11370/11fe1269-08a7-47bf-b99a-0c8884567444
https://hdl.handle.net/11370/11fe1269-08a7-47bf-b99a-0c8884567444
Publikováno v:
European Journal of Pharmaceutical Sciences, 23(2), 169-179. ELSEVIER SCIENCE BV
In this study the effect of different vessel wall materials on the granule size distributions obtained during high-shear granulation of different materials is investigated. The distributions obtained in glass and stainless steel vessels differ from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313cc65bd29541177133c4f72d94d3db
https://research.rug.nl/en/publications/7be4edfd-4500-4da7-af1d-071045d06af4
https://research.rug.nl/en/publications/7be4edfd-4500-4da7-af1d-071045d06af4
Publikováno v:
Powder Technology, 146(1-2), 66-72
This study evaluates methods used for granule shape characterization. The aim is to identify an optimal combination of shape factors to measure granule shape and roughness.Granules were prepared from microcrystalline cellulose (MCC), alpha-lactose, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9410d8584c144422adecd6b24872763
https://research.rug.nl/en/publications/910fca7c-4f51-491f-b9be-269ae24aea62
https://research.rug.nl/en/publications/910fca7c-4f51-491f-b9be-269ae24aea62