Zobrazeno 1 - 10
of 58
pro vyhledávání: '"A.M. Bonin"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 398:111-121
4,4'-Methylenebis(2-chlororaniline) (MOCA) is a suspect human carcinogen that has wide use as an industrial compound. Occupationally, exposure may occur through inhalation and ingestion, but skin absorption is the main route by which this compound ga
Autor:
Carolyn T. Dillon, M. Cholewa, Sebastian M. Marcuccio, G.J.F. Legge, Helmut Weigold, Peter A. Lay, I. F. Turnbull, George Holan, E. Tomlinson, A.M. Bonin, Peter J. Wright
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 104:317-323
The use of micro-PIXE [1] in measuring the quantitative uptake of drugs containing metal atoms by individual Vero cells (African green monkey kidney cell line) and V79 Chinese hamster lung cells is demonstrated. One class of drugs, heteropolytungstat
Publikováno v:
Carcinogenesis. 13:329-332
The most potent carcinogen of the cyclopenta[a]phenanthrene series, 15, 16-dihydro-11-methylcyclopenta[a]phenanthren-17-one and its non-carcinogenic, unmethylated parent compound, were compared for their abilities to induce micronuclei in epidermal k
Publikováno v:
Mutagenesis. 7:199-203
Phorbol esters are chemical compounds which have the ability to promote carcinogenesis in the skin of mice. In the HRA/Skh mouse strain, an initiation-promotion assay substantiated evidence that mezerein acts as a complete promoter. Complete promotio
Publikováno v:
Mutation research. 283(1)
Amitrole is a herbicide which has been found to induce thyroid and liver tumours in rodents, yet demonstrates limited genotoxic activity. The lack of mutagenicity of this compound in Salmonella typhimurium when employing a standard liver microsomal f
Publikováno v:
Mutagenesis. 6(5)
Micronucleus (MN) induction in cultured keratinocytes was investigated following skin painting of HRA/Skh mice with the pesticide, dichlorvos. Whole skin and partially-purified epidermal cells from 5-6 week old male animals were cultured for 4 days i
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 28(3)
Mutagen production was examined in lamb and beef in relation to certain common household cooking methods. Mutagenicity was assessed, after extraction of the basic fraction of cooked meat samples, using Salmonella typhimurium strain TA1538 with added
Publikováno v:
Toxicology Letters. 95:147
Autor:
Philip Hendry, R.J. Judd, Gregory Barr-David, Peter A. Lay, Nicholas E. Dixon, R.S.U. Baker, B.D. Martin, Jennifer A. Irwin, A.M. Bonin, Rodney P. Farrell
Publikováno v:
Journal of Inorganic Biochemistry. 43:466
Publikováno v:
Carcinogenesis. 10:2119-2122
The mutagenic properties of Ethacure 300, Cyanacure and Polacure 740M, all possible substitutes for the industrial carcinogen, 4,4'-methylene bis(2-chloroaniline), have been determined in Salmonella typhimurium strains TA100, TA98, TA1535 and TA1537.