Zobrazeno 1 - 10
of 65
pro vyhledávání: '"A.L. Muggleton-Harris"'
Publikováno v:
Human Reproduction. 10:183-192
Cultured human preimplantation embryos have been used to develop methods which allow preimplantation genetic diagnosis (PGD) analyses by polymerase chain reaction (PCR) and fluorescent in-situ hybridization (FISH) on biopsied blastomeres and trophect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f407685202c0eb07d94215d1d6ed354
https://doi.org/10.1093/humrep/10.1.183
https://doi.org/10.1093/humrep/10.1.183
Publikováno v:
Human Reproduction. 8:2197-2205
Cultured human blastocysts have been biopsied on day 5-6 post insemination and 2-6 extra-embryonic cells from the trophectoderm were removed and their DNA subjected to specific amplification by the polymerase chain reaction (PCR). Simultaneous amplif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c540c326a7d2aa91050d88b9c67e08af
https://doi.org/10.1093/oxfordjournals.humrep.a138003
https://doi.org/10.1093/oxfordjournals.humrep.a138003
Autor:
I. Findlay, A.L. Muggleton-Harris, Virginia N. Bolton, S.A. Sheardown, M. Mitchell, D.M. Layton, A. Turner, D. Greaves
Publikováno v:
Scopus-Elsevier
The preimplantation diagnosis of a HbSA-globin transgene in biopsied trophectoderm cells and blastomeres in embryos using a transgenic mouse model for the trait of human sickle-cell anaemia has been undertaken. A sensitive procedure was developed for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e037164d84d8a73936df2e57c8ea6c
https://doi.org/10.1093/oxfordjournals.humrep.a137845
https://doi.org/10.1093/oxfordjournals.humrep.a137845
Publikováno v:
Human reproduction (Oxford, England). 10(11)
In-house prepared medium was used routinely in our in-vitro fertilization (IVF) facility prior to the introduction of the commercial 'Medi-Cult' products. A comparative study of the in-vitro development of embryos cultured in two [T6 and Earle's bala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939cf0ce0ab7d286b53c73d5c65e6e70
https://pubmed.ncbi.nlm.nih.gov/8747058
https://pubmed.ncbi.nlm.nih.gov/8747058
Autor:
C.E. Patek, A.H. Handyside, K. Hardy, J.B. Kerr, Martin L. Hooper, K. W. Jones, R.G. Gosden, A.L. Muggleton-Harris, D.G. Whittingham
Publikováno v:
Development (Cambridge, England). 113(1)
Adult intraspecific mouse chimaeras, derived by introducing male embryonal stem cells into unsexed host blastocysts, were examined to determine whether gonadal sex was correlated with the sex chromosome composition of particular cell lineages. The fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c9c5e2c105100af01849a16d97c386
https://pubmed.ncbi.nlm.nih.gov/1765003
https://pubmed.ncbi.nlm.nih.gov/1765003
Publikováno v:
Experimental Eye Research. 32:563-573
When individual lens epithelial cells from normal and cataractous mice are cloned, they undergo a finite number of replications in culture. Within each clone there is a heterogeneity of replicative states. The Nakano cataractous lens cells have far g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336d6658525b3ed94a104435f5870496
https://doi.org/10.1016/s0014-4835(81)80005-x
https://doi.org/10.1016/s0014-4835(81)80005-x
Publikováno v:
Mechanisms of Ageing and Development. 19:37-43
Confluent cultured normal human skin fibroblasts from neonatal, adult and aged donors have been stimulated to respond to wounding of the cell sheet. The latent period prior to initial migration of cells from the leading edge of the monolayer is corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dafd997ecac4015fcb73eebea28dc4
https://doi.org/10.1016/0047-6374(82)90048-3
https://doi.org/10.1016/0047-6374(82)90048-3
Publikováno v:
Development. 99:473-480
In the study of the lens of a congenital cataractous mouse mutant (CAT), it has been shown that a loss of growth regulation at the cellular level causes gross lens abnormalities. The phenotypic characteristics of the cataractous mouse lens are simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf3b7c17dad154e662cffbccb02fc08
https://doi.org/10.1242/dev.99.4.473
https://doi.org/10.1242/dev.99.4.473
Autor:
A.L. Muggleton-Harris
Publikováno v:
Experimental Gerontology. 6:461-468
Adult frog lens cell nuclei resting in the G1 phase of the cell cycle were transplanted into recipient eggs with negative results as far as cleavage or development was concerned. If these donor cells were stimulated to undergo mitosis and they were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fc07a3c22d1a552430cc44a6898d81
https://doi.org/10.1016/0531-5565(71)90025-8
https://doi.org/10.1016/0531-5565(71)90025-8
Autor:
A.L. Muggleton-Harris
Publikováno v:
Experimental Gerontology. 6:279-285
An improved method for isolating donor cells from amphibian lens tissue is described. Nuclei from the embryonic and adult frog lens cells were transplanted into prepared, parthogenetically activated, enucleated eggs. The activity and stage of develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8cb5a878d6ab54cd7a9dee2ab233b7
https://doi.org/10.1016/0531-5565(71)90009-x
https://doi.org/10.1016/0531-5565(71)90009-x