Biochemical characterization of adenosine deaminase (CD26; EC 3.5.4.4) activity in human lymphocyte-rich peripheral blood mononuclear cells

Autor: F.F. Zanoelo, A.K.Y. de Souza, Fabrício Figueiró, Juliete Nathali Scholl, J.A. dos Santos Jaques, Ana Maria Oliveira Battastini, L.R. Costa

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 54, Iss 8 (2021)
Brazilian Journal of Medical and Biological Research
Brazilian Journal of Medical and Biological Research, Volume: 54, Issue: 8, Article number: e10850, Published: 24 MAY 2021
Brazilian Journal of Medical and Biological Research v.54 n.8 2021
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC

The conversion of adenosine to inosine is catalyzed by adenosine deaminase (ADA) (EC 3.5.4.4), which has two isoforms in humans (ADA1 and ADA2) and belongs to the zinc-dependent hydrolase family. ADA modulates lymphocyte function and differentiation,

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