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Connexin 43 maintains tissue polarity and regulates mitotic spindle orientation in the breast epithelium

Autor: Shirisha Chittiboyina, Sophie A. Lelièvre, Pierre-Alexandre Vidi, Rabih S. Talhouk, Sabreen F. Fostok, Jennifer Sturgis, Kurt B. Hodges, Lei Wang, Gurushankar Chandramouly, A.K Urazaev, Iliana Tenvooren, Dana Bazzoun, Hibret A. Adissu

Publikováno v: J Cell Sci

Cell–cell communication is essential for tissue homeostasis, but its contribution to disease prevention remains to be understood. We demonstrate the involvement of connexin 43 (Cx43, also known as GJA1) and related gap junction in epithelial homeos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a51feb6e0e10c38093ed1ecab72e8c
https://doi.org/10.1242/jcs.223313

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Increased non-quantal release of acetylcholine after inhibition of endocytosis by methyl-β-cyclodextrin: the role of vesicular acetylcholine transporter

Autor: Andrey L. Zefirov, A.K Urazaev, K.V. Uzinskaya, N. V. Naumenko, Alexey M. Petrov, A. R. Giniatullin

Publikováno v: Neuroscience. 186:1-12

We investigated the role of the vesicular acetylcholine transporter in the mechanism of non-quantal (non-vesicular) secretion of neurotransmitter in the neuromuscular synapse of the rat diaphragm muscle. Non-quantal secretion was estimated electrophy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3affdce2603739ead04767aca062ed3
https://doi.org/10.1016/j.neuroscience.2011.04.051

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Glutamate regulation of non-quantal release of acetylcholine in the rat neuromuscular junction

Autor: A.K Urazaev, Eugen E. Nikolsky, A. I. Malomouzh, Edward M. Lieberman, M. R. Mukhtarov, Vyskocil F

Publikováno v: Journal of Neurochemistry. 85:206-213

Glutamate, previously demonstrated to participate in regulation of the resting membrane potential in skeletal muscles, also regulates non-quantal acetylcholine (ACh) secretion from rat motor nerve endings. Non-quantal ACh secretion was estimated by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddc04d9e3b168a1d942f3ea039029518
https://doi.org/10.1046/j.1471-4159.2003.01660.x

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Properties of glutaminase of crayfish CNS: implications for axon–glia signaling

Autor: J.A Engler, J.C Harkins, J.M Gottesman, Robert M. Grossfeld, A.K Urazaev, Edward M. Lieberman

Publikováno v: Neuroscience. 114:699-705

Glutaminase of crayfish axons is believed to participate in recycling of axon-glia signaling agent(s). We measured the activity and properties of glutaminase in crude homogenates of crayfish CNS, using ion exchange chromatography to separate radiolab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde51a107fc6d6507e5a3cf939f57454
https://doi.org/10.1016/s0306-4522(02)00357-3

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Mechanism of NMDA receptor contribution to axon-to-glia signaling in the crayfish medial giant nerve fiber

Autor: B. S. Gafurov, Robert M. Grossfeld, A.K Urazaev, Edward M. Lieberman

Publikováno v: Glia. 38:80-86

Electrical stimulation of crayfish giant axons at high frequency activates group II metabotropic and NMDA glutamate receptors on adjacent glial cells via release of N-acetylaspartylglutamate and glutamate formed upon its hydrolysis. This produces a t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bbabb7f2257417448dae6056b1d701
https://doi.org/10.1002/glia.10042

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N-Acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber

Autor: A.K Urazaev, Edward M. Lieberman, B. S. Gafurov, Robert M. Grossfeld

Publikováno v: Neuroscience. 106:227-235

Glial cell hyperpolarization previously has been reported to be induced by high frequency stimulation or glutamate. We now report that it also is produced by the glutamate-containing dipeptide N-acetylaspartylglutamate (NAAG), by its non-hydrolyzable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7805a9468d4573016ce085e66ad04ab
https://doi.org/10.1016/s0306-4522(01)00271-8

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Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium

Autor: Elikplimi K. Asem, Cedric Plachot, Lesley S. Chaboub, Jennifer Sturgis, Sophie A. Lelièvre, Lei Wang, Hibret A. Adissu, A.K Urazaev

Publikováno v: BMC Biology
BMC Biology, Vol 7, Iss 1, p 77 (2009)

Background Basoapical polarity in epithelia is critical for proper tissue function, and control of proliferation and survival. Cell culture models that recapitulate epithelial tissue architecture are invaluable to unravel developmental and disease me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8ba96866d45f48ca45ba6afc0cc06b
https://pubmed.ncbi.nlm.nih.gov/19917093

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Effect of N-acetylaspartylglutamate (NAAG) on non-quantal and spontaneous quantal release of acetylcholine at the neuromuscular synapse of rat

Autor: A.K Urazaev, Edward M. Lieberman, Jane L. Lubischer, Eugen E. Nikolsky, Robert M. Grossfeld, A. I. Malomouzh, Jessica A. Sherman

Publikováno v: Journal of neurochemistry. 94(1)

N-Acetylaspartylglutamate (NAAG), known to be present in rat motor neurons, may participate in neuronal modulation of non-quantal secretion of acetylcholine (ACh) from motor nerve terminals. Non-quantal release of ACh was estimated by the amplitude o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f02cfaef18de17628e6afe43d2325f4
https://pubmed.ncbi.nlm.nih.gov/15953368

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