White matter changes and gait decline in cerebral small vessel disease

Autor: H.M. van der Holst, A.M. Tuladhar, V. Zerbi, I.W.M. van Uden, K.F. de Laat, E.M.C. van Leijsen, M. Ghafoorian, B. Platel, M.I. Bergkamp, A.G.W. van Norden, D.G. Norris, E.J. van Dijk, A.J. Kiliaan, F.-E. de Leeuw

Publikováno v: NeuroImage: Clinical, Vol 17, Iss , Pp 731-738 (2018)

The relation between progression of cerebral small vessel disease (SVD) and gait decline is uncertain, and diffusion tensor imaging (DTI) studies on gait decline are lacking. We therefore investigated the longitudinal associations between (micro) str

Externí odkaz: https://doaj.org/article/4837e056dd064a8a9a4ab1d368d3a86b

Diffusion tensor imaging of the hippocampus predicts the risk of dementia; the RUN DMC study

Autor: H.M. van der Holst, Roy P. C. Kessels, A.G.W. van Norden, F-E de Leeuw, Anil M. Tuladhar, Loes C.A. Rutten-Jacobs, David G. Norris, E.M.C. van Leijsen, E.J. van Dijk, K.F. de Laat, Jurgen A.H.R. Claassen, I.W.M. van Uden

Publikováno v: Human Brain Mapping. 37:327-337

INTRODUCTION: Cerebral small vessel disease is one of the most important risk factors for dementia, and has been related to hippocampal atrophy, which is among the first observed changes on conventional MRI in patients with dementia. However, these v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0371e9e80ff5dc966a7061b51194813b
https://doi.org/10.1002/hbm.23029

Dementia: Alzheimer pathology and vascular factors: From mutually exclusive to interaction

Autor: A.G.W. van Norden, P. Scheltens, M.G.M. Olde Rikkert, K.F. de Laat, F.E. de Leeuw, E.J. van Dijk

Publikováno v: van Norden, A G W, van Dijk, E J, de Laat, K F, Scheltens, P, Olde Rikkert, M G M & de Leeuw, F E 2012, ' Dementia: Alzheimer pathology and vascular factors: From mutually exclusive to interaction ', Biochimica et Biophysica Acta. Molecular Basis of Disease, vol. 1822, no. 3, pp. 340-349 . https://doi.org/10.1016/j.bbadis.2011.07.003
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1822, 340-9
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1822, 3, pp. 340-9
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1822(3), 340-349. Elsevier

Contains fulltext : 110813.pdf (Publisher’s version ) (Closed access) Alzheimer's disease (AD) is the most common type of dementia. Both its incidence and prevalence are expected to increase exponentially as populations' age worldwide. Despite impr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4f13d9d30b66595df17e7cd0ce39a4
https://doi.org/10.1016/j.bbadis.2011.07.003

White matter integrity in small vessel disease is related to cognition

Autor: K.F. de Laat, David G. Norris, Marcel P. Zwiers, Anil M. Tuladhar, F.E. de Leeuw, E.J. van Dijk, A.G.W. van Norden

Publikováno v: Neuroimage. Clinical, 7, pp. 518-524
Neuroimage. Clinical, 7, 518-524
NeuroImage : Clinical
NeuroImage: Clinical, 7, 518-524. Elsevier
NeuroImage: Clinical, Vol 7, Iss C, Pp 518-524 (2015)

Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes of presumed vascular origin, is common in elderly people and is related to cognitive impairment and dementia. One possible mechanism could be the disruption of w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140b1519867f01129aea29949e321209
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/154451

Depressive Symptoms and Amygdala Volume in Elderly with Cerebral Small Vessel Disease: The RUN DMC Study

Autor: Marcel P. Zwiers, K.F. de Laat, F-E. de Leeuw, I.W.M. van Uden, Indira Tendolkar, L.J.B. Van Oudheusden, A.G.W. van Norden, Rob A.R. Gons

Publikováno v: Journal of Aging Research, 2011, pp. 647869-647869
van Uden, I W M, van Norden, A G W, de Laat, K F, van Oudheusden, L J B, Gons, R A R, Tendolkar, I, Zwiers, M P & de Leeuw, F-E 2011, ' Depressive Symptoms and Amygdala Volume in Elderly with Cerebral Small Vessel Disease : The RUN DMC Study ', Experimental Aging Research, vol. 2011, pp. 647869 . https://doi.org/10.4061/2011/647869
Journal of Aging Research, 2011, 647869-647869
Experimental Aging Research, 2011. Taylor and Francis Ltd.
Journal of Aging Research, Vol 2011 (2011)
Journal of Aging Research

Introduction. Late onset depressive symptoms (LODSs) frequently occur in elderly with cerebral small vessel disease (SVD). SVD cannot fully explain LODS; a contributing factor could be amygdala volume. We investigated the relation between amygdala vo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206e6ff5633ea29297a471fc56967044
https://hdl.handle.net/2066/97796