Zobrazeno 1 - 10
of 34
pro vyhledávání: '"A.G.B. Templeton"'
Publikováno v:
British Journal of Pharmacology. 119:277-282
1. The 5-hydroxytryptamine (5-HT) receptors mediating contraction of human isolated pulmonary artery rings were investigated. Responses to the agonists 5-carboximidotryptamine (5-CT, non-selective 5-HT1 agonist), sumatriptan (5-HT1D-like receptor ago
Autor:
Clayton Ra, E. D. Johnston, Margaret R. MacLean, M. Baird, G. Sweeney, A.G.B. Templeton, Sheridan S
Publikováno v:
Journal of Cardiovascular Pharmacology. 26:751-760
We examined responses to the 5-hydroxy-tryptamine 1D (5-HT 1D )-receptor agonist sumatriptan in bovine pulmonary artery rings (2-3 mm ID). The effects of agonist-induced tone and agents that alter intracellular cyclic AMP [cyclic AMP] i or [cyclic GM
Autor:
V. G. Wilson, Craig J. Daly, David J. Miller, John C. McGrath, John O’Dowd, A.G.B. Templeton, G. Singh, M. Nagadeh, C. M. Brown, A. MacKinnon, Anne O'Dowd, David A. Kendall, Darawan Pinthong
Publikováno v:
Annals of the New York Academy of Sciences. 763:591-605
This article brings together work on imidazoline or imidazole-containing compounds concerned with the pharmacology of alpha-adrenoceptors, principally on smooth muscle, to illustrate how imidazolines have contributed to the subclassification of alpha
Publikováno v:
Placenta. 15:715-720
A role for atrial natriuretic peptide (ANP) in maintaining low vascular resistance within the fetoplacental circulation was investigated using isolated strips of human umbilical artery (HUA). Physiological levels of ANP significantly reduced the isom
Autor:
A.J. Peacock, Margaret R. MacLean, R.A. Clayton, P.D. McIntyre, A.G.B. Templeton, S.W. Hillis
Publikováno v:
Pulmonary Pharmacology. 7:65-72
Summary: Vasoconstrictor responses to 5-hydroxytryptamine (5-HT) and the 5-HT 1D receptor agonist sumatriptan were studied in isolated bovine pulmonary artery rings. The effects of the antagonists, ketanserin (5-HT 2A -receptors) and methiothepin (5-
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H1878-H1883
It has previously been shown that human umbilical artery (HUA) smooth muscle produces thromboxane A2 in response to increasing oxygen levels and that this thromboxane promotes contraction. To investigate the intracellular action of thromboxane A2, st
Publikováno v:
British Journal of Pharmacology. 99:77-86
1. The effects of an endothelium-dependent (acetylcholine) and an endothelium-independent (sodium nitroprusside) relaxant against noradrenaline-induced contractions were compared in three isolated superficial blood vessels of the rabbit, the lateral
Publikováno v:
Cardiovascular research. 28(9)
Objective: The aim was to investigate the effect of altered bathing pH on calcium activated force generated by the contractile proteins in an α toxin permeabilised phasic (rat portal vein) and tonic (human umbilical artery) smooth muscle. Methods: S
Publikováno v:
Placenta. 14(5)
The contractile properties of the umbilical artery to oxygen, U46619 (a stable thromboxane A2 mimetic) and 5-hydroxytryptamine (5-HT) were studied in normal term (> or = 37 weeks) and preterm (< 34 weeks) pregnancies, and in a group of pregnancies co
Publikováno v:
British journal of pharmacology. 106(4)
1. The vasoconstrictor effect of endothelin-1 (3 x 10(-11) M-10(-7) M) was studied in successive generations of blood vessels of the foeto-placental vascular tree. These were the human umbilical arteries and veins, primary surface chorionic plate art