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pro vyhledávání: '"A.G. Wrobel"'
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Autor:
Dhira Joshi, Lucy R. Marshall, Lucy R. Wedderburn, Stavroula Paraskevopoulou, Steve Gamblin, Georgina H. Cornish, Sonia Gandhi, Charles Swanton, John W. McCauley, William Bolland, Svend Kjaer, Nikhil Faulkner, Hannah Rickman, Rachel Ulferts, Philip Hobson, D.J. Benton, Laura E. McCoy, Ana Agua-Doce, Rupert Beale, Annachiara Rosa, Chloe Roustan, Nicola O’Reilly, Catherine F Houlihan, Christopher Earl, Eleni Nastouli, A.G. Wrobel, Rachael Thompson, Brigitta Stockinger, Kirsty Thomson, Catherine Moore, Bethany R. Jebson, Anna Radziszewska, Coziana Ciurtin, Andrew Riddell, Saira Hussain, Emilie Sanchez, Peter Cherepanov, Elizabeth C. Rosser, Meredyth G. Ll Wilkinson, Kevin W. Ng, Ruth Harvey, Philip A. Walker, Hannah Peckham, Judith Heaney, Gee Yen Shin, Moira J. Spyer, George Kassiotis
Publikováno v:
Science (New York, N.y.)
Science
Science
Antibodies predating infection Immunological memory after infection with seasonal human coronaviruses (hCoVs) may potentially contribute to cross-protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ng et al. report that i
Autor:
A.G. Wrobel, Andreas Wack, Jack Major, William Bolland, Jan Attig, Steve Gamblin, Kevin W. Ng, George R. Young, George Kassiotis
Publikováno v:
Nature genetics
Nature Genetics
Nature Genetics
Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and a regulator of several physiological processes. ACE2 has recently been proposed to be interferon-inducible, suggesting th
Autor:
D.J. Benton, Chloe Roustan, John J. Skehel, Stephen R. Martin, Steven J. Gamblin, A.G. Wrobel, Peter B. Rosenthal, Pengqi Xu
Publikováno v:
Nature
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is initiated by virus binding to the ACE2 cell-surface receptors1-4, followed by fusion of the virus and cell membranes to release the virus genome into the cell. Both recept
Autor:
John J. Skehel, Stephen R. Martin, A.G. Wrobel, Peter B. Rosenthal, Chloe Roustan, Saira Hussain, Annabel Borg, Steve Gamblin, D.J. Benton
Recently emerged variants of SARS-CoV-2 contain in their surface spike glycoproteins multiple substitutions associated with increased transmission and resistance to neutralising antibodies. We have examined the structure and receptor binding properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741046cad28d5321ce3b490fbc6f2c74
Autor:
John J. Skehel, Annabel Borg, D.J. Benton, Pengqi Xu, Chloe Roustan, A.G. Wrobel, Peter B. Rosenthal, Stephen R. Martin, S.J. Gamblin
Publikováno v:
Proceedings of the National Academy of Sciences. 118
The authors note that on page 3, left column, first paragraph, line 5, “K848” should instead appear as “K854.” The online version has been corrected.
Publikováno v:
Seminars in Immunology
Coronaviruses are evolutionarily successful RNA viruses, common to multiple avian, amphibian and mammalian hosts. Despite their ubiquity and potential impact, knowledge of host immunity to coronaviruses remains incomplete, partly owing to the lack of
Autor:
Chloe Roustan, D.J. Benton, Lesley J. Calder, Pengqi Xu, Steven J. Gamblin, A.G. Wrobel, John J. Skehel, Peter B. Rosenthal, Stephen R. Martin, Annabel Borg
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Coronaviruses of bats and pangolins have been implicated in the origin and evolution of the pandemic SARS-CoV-2. We show that spikes from Guangdong Pangolin-CoVs, closely related to SARS-CoV-2, bind strongly to human and pangolin ACE2 receptors. We a
Autor:
A.G. Wrobel, Peter B. Rosenthal, Svend Kjaer, George Kassiotis, Richard S. Tedder, Judith Heaney, Andrea Nans, Moira Spyer, Eleni Nastouli, Valerie E. Pye, Charlotte-Eve Short, Eleanor Parker, Andy Riddell, Chloe Rees-Spear, Annachiara Rosa, Nicola J. Cook, Graham P. Taylor, Chloe Roustan, Michael Fertleman, Carl Graham, Marit J. van Gils, Alberto Susana, Rogier W. Sanders, Mariana Silva dos Santos, Peter Cherepanov, Rachel Ulferts, Myra O. McClure, Luke Muir, Michael H. Malim, Hefin Rhys, Massimo Pizzato, Laura E. McCoy, James I. MacRae, Evangelos Christodoulou, Jeffrey Seow, Kevin W. Ng, Rupert Beale, Katie J. Doores, Laura Masino, Carolina Rosadas
Publikováno v:
Science Advances
SARS-CoV-2 spike N-terminal domain harbors a potent epitope that can be modulated by binding of natural linear tetrapyrroles.
The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies. We show that SARS-CoV-2
The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies. We show that SARS-CoV-2
Autor:
A.G. Wrobel, John J. Skehel, Peter B. Rosenthal, Steven J. Gamblin, Stephen R. Martin, Chloe Roustan, D.J. Benton, Annabel Borg, Pengqi Xu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences
Proc Natl Acad Sci U S A
Significance The spike proteins of most current severe acute respiratory syndrome coronavirus 2 isolates contain a D614G substitution, by comparison with the spike protein of initial isolates. In this study we present high-resolution, single-particle