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Three-dimensional printed personalized drug devices with anatomical fit: a review

Autor: Marcilio Cunha-Filho, Ludmila A.G. Pinho, Ricardo Neves Marreto, Guilherme M. Gelfuso, Tais Gratieri

Publikováno v: Journal of Pharmacy and Pharmacology. 74:1391-1405

Objectives Three-dimensional printing (3DP) has opened the era of drug personalization, promising to revolutionize the pharmaceutical field with improvements in efficacy, safety and compliance of the treatments. As a result of these investigations, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d433f790d775af79fb0dfe55e3301d
https://doi.org/10.1093/jpp/rgab146

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Granules of finasteride and cyclodextrin obtained by hot-melt extrusion to target the hair follicles

Autor: Guilherme M. Gelfuso, Livia L. Sa-Barreto, Tais Gratieri, Ludmila A.G. Pinho, Stephania G.B. Lima, Marcilio Cunha-Filho

Publikováno v: Powder Technology. 391:311-320

This study aimed to develop topical granules of finasteride (FIN) with a follicular targeting potential to treat androgenic alopecia. In this sense, FIN inclusion complexes with cyclodextrin produced by two different methods (nanospray-drying and rot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba3dc38639c1e67c5615be8a2b36187c
https://doi.org/10.1016/j.powtec.2021.06.027

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Quantification of CO2 emission reductions from energy efficiency actions and solar photovoltaic generation at the Federal Institute of Education, Science, and Technology of Goiás

Autor: Elder Geraldo Domingues, Luane Schiochet Pinto, A.F. Faria, M.A. Vidal, A. H. M. Stach, A.G. Pinho, Daywes Pinheiro Neto

Publikováno v: Renewable Energy and Power Quality Journal. 19:45-50

In 2016, the Brazilian Agency of Electric Energy launched a public call for research and development projects to reduce barriers to implementing energy efficiency projects and own electricity generation. One objective of this public call was to encou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::670b17a518edf9ce97b8ffdcd3eb7917
https://doi.org/10.24084/repqj19.209

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Medicated lacquer for application on adornments to treat affections in aesthetic perforations

Autor: Ludmila A.G. Pinho, Ana Luiza Lima, Livia L. Sa-Barreto, Guilherme M. Gelfuso, Tais Gratieri, Ricardo Neves Marreto, Yong Chen, Marcilio Cunha-Filho

Publikováno v: International journal of pharmaceutics. 627

Aesthetic perforations are often associated with health issues, such as itching, inflammation, or microbial infection. Accordingly, this work proposed a lacquer to be applied on the adornment accessory forming a film from which a proper drug is relea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032378bdf015b3bd975e118934dbecae
https://pubmed.ncbi.nlm.nih.gov/36179928

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Preformulation Studies to Guide the Production of Medicines by Fused Deposition Modeling 3D Printing

Autor: Ricardo Neves Marreto, Guilherme M. Gelfuso, Livia L. Sa-Barreto, Marcilio Cunha-Filho, Tais Gratieri, Ludmila A.G. Pinho, Ana Luiza Lima

Publikováno v: AAPS PharmSciTech. 22

Fused deposition modeling (FDM) 3D printing has demonstrated high potential for the production of personalized medicines. However, the heating at high temperatures inherent to this process causes unknown risks to the drug product's stability. The pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b5398e72ec41ddaedb7e4b5536243f
https://doi.org/10.1208/s12249-021-02114-7

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Hot-Melt Extrusion as an Advantageous Technology to Obtain Effervescent Drug Products

Autor: Guilherme M. Gelfuso, Tais Gratieri, Ludmila A.G. Pinho, Marcilio Cunha-Filho, Ricardo Neves Marreto, Livia L. Sa-Barreto, Juliano A. Chaker, Ana Luiza Lima

Publikováno v: Pharmaceutics
Pharmaceutics, Vol 12, Iss 779, p 779 (2020)
Volume 12
Issue 8

Here, we assessed the feasibility of hot-melt extrusion (HME) to obtain effervescent drug products for the first time. For this, a combined mixture design was employed using paracetamol as a model drug. Extrudates were obtained under reduced torque (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbdeb14b10039494ad4fc387818b6f1
http://europepmc.org/articles/PMC7464369

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Thermal analysis used to guide the production of thymol and Lippia origanoides essential oil inclusion complexes with cyclodextrin

Autor: Ludmila A.G. Pinho, Felipe Q. Pires, Izabel Cristina Rodrigues da Silva, Tais Gratieri, Marcilio Cunha-Filho, Daniel Oliveira Freire, Lúcio Cardozo-Filho, Livia L. Sa-Barreto, Guilherme M. Gelfuso

Publikováno v: Journal of Thermal Analysis and Calorimetry. 137:543-553

This study aimed to use thermal analysis and other analytical tools to guide the production of thymol (TML) and essential oil of Lippia origanoides (EO) solid inclusion complexes from a screening of different cyclodextrins (CDs) types and production

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3222632c2c8f0eedeaf1aba3a6597bb7
https://doi.org/10.1007/s10973-018-7956-6

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Autor: Livia L. Sa-Barreto, Ludmila A.G. Pinho, Marcilio Cunha-Filho, Caroline Garcia Ribeiro, Ana Claudia Temer

Publikováno v: Infarma: Pharmaceutical Sciences, Vol 30, Iss 2, Pp 77-84 (2018)

Orodispersible tablets are getting popular due to its easy administration which leads to a higher therapeutic adherence. This study aimed to evaluate the state of the art of these drug products based on the scientific literature. Also, orodispersible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27616cf4c49901103ce55071d8d0127
http://revistas.cff.org.br/?journal=infarma&page=article&op=view&path[]=2309&path[]=pdf

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