Zobrazeno 1 - 10
of 108
pro vyhledávání: '"A.F Kotzé"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Planta Medica. 85:1114-1123
The fruit from various pepper plants has been employed for the seasoning of food, as perfuming agents, and also as traditional medicines. Phytochemicals isolated from different pepper species have been found to modulate the pharmacokinetics of orally
Autor:
Dewald Steyn, Bianca Peterson, A.F Kotzé, Hanna Svitina, Werner Gerber, Ché Weldon, Josias H. Hamman
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 113:107131
Nasal drug administration has been identified as a potential alternative to oral drug administration, especially for systemic delivery of large molecular weight compounds. Major advantages of nasal drug delivery include high vascularity and permeabil
Publikováno v:
Journal of HerbMed Pharmacology, Vol 9, Iss 4, Pp 355-365 (2020)
Introduction: The nasal route of drug administration offers an alternative way for oral drug delivery and has the benefit of avoiding first-pass metabolism through drug delivery directly into the systemic circulation. The drug absorption enhancing ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb2c001ca2f00330bf419da40cd04e4
https://hdl.handle.net/10394/36000
https://hdl.handle.net/10394/36000
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 940-950 (2019)
Toxicology Reports, Vol 6, Iss, Pp 940-950 (2019)
Graphical abstract
Highlights • Acute administration of 2000 mg/kg of the Pheroid® delivery system was tolerated upon intravenous administration in BALB/c mice and Sprague-Dawley rats. • Oral administration was tolerated in both acute toxic
Highlights • Acute administration of 2000 mg/kg of the Pheroid® delivery system was tolerated upon intravenous administration in BALB/c mice and Sprague-Dawley rats. • Oral administration was tolerated in both acute toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3932da74caa5db95d43f42b121f5625a
https://www.sciencedirect.com/science/article/pii/S2214750018301835/pdfft?md5=873dd031b7b7b9553b8d82e3da2c86ec&pid=1-s2.0-S2214750018301835-main.pdf
https://www.sciencedirect.com/science/article/pii/S2214750018301835/pdfft?md5=873dd031b7b7b9553b8d82e3da2c86ec&pid=1-s2.0-S2214750018301835-main.pdf
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 106 (2018)
Pharmaceutics
Pharmaceutics
Simultaneous oral intake of herbs, supplements, foods and drugs with other drug(s) may result in pharmacokinetic or pharmacodynamic interactions with the latter. Although these interactions are often associated with unwanted effects such as adverse e
Publikováno v:
Journal of Pharmacy and Pharmacology. 66:14-22
Objectives Mefloquine (MQ) is an antimalarial drug with high efficacy, often used in the treatment and chemoprophylaxis of malaria. However, it has low solubility in water, a long elimination half-life (4 days), and is neurotoxic, which leads to unwa
Publikováno v:
Current Drug Delivery. 10:348-356
Chitosan is a polymer derived from chitin that is widely available at relatively low cost, but due to compression challenges it has limited application for the production of direct compression tablets. The aim of this study was to use certain process
Publikováno v:
Drug Development and Industrial Pharmacy. 29:61-69
Previous studies have established that N-trimethyl chitosan chloride (TMC) is a potent absorption enhancer for peptides and large hydrophilic compounds across mucosal surfaces, especially in neutral and basic environments where chitosan is ineffectiv
Publikováno v:
Drug Development and Industrial Pharmacy. 29:161-172
N-trimethyl chitosan chloride (TMC) is a polycation that enhances drug transport across epithelia by opening tight junctions. The degree of quaternization of TMC determines the number of positive charges available on the molecule for interactions wit