Výsledky vyhledávání - "A.D.G. de Roos"

The linear C-terminal regions of epidermal growth factor (EGF) and transforming growth factor-α bind to different epitopes on the human EGF receptor

Autor: M.J.H. van Vugt, E.J.J. van Zoelen, M.L.M. van de Poll, A.D.G. de Roos, Anne E.G. Lenferink

Publikováno v: Biochemical Journal, 336, 147-151
Biochemical Journal, 336, pp. 147-151
Europe PubMed Central

Epidermal growth factor (EGF) and transforming growth factor-alpha (TGFalpha) bind with similar affinities in a competitive fashion to the human EGF receptor, and basically induce similar mitogenic responses. In spite of the fact that EGF and TGFalph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a001a7d31c607889a8e291d8c77b1b
https://doi.org/10.1042/bj3360147

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Synchronized calcium spiking resulting from spontaneous calcium action potentials in monolayers of NRK fibroblasts

Autor: A.D.G. de Roos, P.H.J. Peters, Alexander P.R. Theuvenet, E.J.J. van Zoelen, Peter H.G.M. Willems

Publikováno v: Cell Calcium, 22, 195-207. Churchill livingstone
Cell Calcium, 22, pp. 195-207
Cell Calcium, 22, 195-207
Cell Calcium, 22, 3, pp. 195-207

The correlation between the intracellular Ca2+ concentration ([Ca2+]i) and membrane potential in monolayers of density-arrested normal rat kidney (NRK) fibroblasts was investigated. Using the fluorescent probe Fura-2, spontaneous repetitive spike-lik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8bc63bbd783a3d8efd9321fd9d80fb
https://doi.org/10.1016/s0143-4160(97)90013-0

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Generation and characterization of radiation reduced cell hybrids and isolation of probes from the proximal short arm of the human X chromosome

Autor: Helene Achatz, S.D. van der Velde-Visser, Alfons Meindl, Thomas Meitinger, B. de Leeuw, Frans P.M. Cremers, T.J.R. van de Pol, H. H. Ropers, Wolfgang Berger, A.D.G. de Roos, A. Geurts van Kessel

Publikováno v: Human Genetics. 90:243-246

Employing a modified Goss-Harris irradiation fusion protocol, we have generated a panel of somatic cell hybrids containing various overlapping fragments of the Xcen-Xp11.4 interval. This region of the human X chromosome is known to carry genes for se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e88b7e962d3b46ec3a0ba93b733778
https://doi.org/10.1007/bf00220070

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Synchronized Ca2+ signaling by intercellular propagation of Ca2+ action potentials in NRK fibroblasts

Autor: A.D.G. de Roos, Peter H.G.M. Willems, E.J.J. van Zoelen, Alexander P.R. Theuvenet

Publikováno v: Europe PubMed Central

The intercellular propagation of Ca2+waves by diffusion of inositol trisphosphate has been shown to be a general mechanism by which nonexcitable cells communicate. Here, we show that monolayers of normal rat kidney (NRK) fibroblasts behave like a typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb19a23f0196b72644f43cd3bc1e3f87
https://pubmed.ncbi.nlm.nih.gov/9435495

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Electrophysiological Aspects of Growth Factor Signaling in NRK Fibroblasts: The Role of Intercellular Communication, Membrane Potential and Calcium

Autor: E.J.J. van Zoelen, A.D.G. de Roos, Alexander P.R. Theuvenet

Publikováno v: Wirtz, K.W.A. (ed.), Molecular Mechanisms of Signalling and Membrane Transport, pp. 113-126
Molecular Mechanisms of Signalling and Membrane Transport ISBN: 9783642645594

Normal, non-transformed cells become limited in their growth when cultured at high cell densities. This density-dependent growth inhibition, which is also known as contactinhibition, is one of the most prominent characteristics of non-transformed cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53d2e8a2984a9b9e2fd80fb4065f7bc
https://repository.ubn.ru.nl/handle/2066/249947

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Determination of gap junctional intercellular communication by capacitance measurements

Autor: A.D.G. de Roos, Alexander P.R. Theuvenet, E.J.J. van Zoelen

Publikováno v: Pflügers Archiv : European Journal of Physiology, 431, 4, pp. 556-563
Pflügers Archiv : European Journal of Physiology, 431, 556-563. Springer verlag

Electrical coupling between cells is usually measured using the double patch-clamp technique with cell pairs. Here, a single patch-clamp technique that is not limited to cell pairs is described to determine electrical coupling between cells. Capacita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe1c31bc890c621f0e74b607133b6b9
https://hdl.handle.net/2066/29216

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Lysophosphatidic acid and bradykinin have opposite effects on phenotypic transformation of normal rat kidney cells

Autor: D. C. G. J. Van Alewijk, E.J.J. van Zoelen, A.D.G. de Roos, Gijs B. Afink

Publikováno v: Journal of Cellular Biochemistry, 56, 4, pp. 480-489
Journal of cellular biochemistry, 56(4), 480-489. Wiley-Liss Inc.
Journal of Cellular Biochemistry, 56, 480-489

The bioactive lipid lysophosphatidic acid is besides a strong mitogen for quiescent fibroblasts, a potent inducer of phenotypic transformation of normal rat kidney cells. The lysophosphatidic acid induced loss of density-arrest is strongly inhibited

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177b5ea92adc159c1d2a98f8428a5a7e
https://doi.org/10.1002/jcb.240560408

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Bradykinin-induced growth inhibition of normal rat kidney (NRK) cells is paralleled by a decrease in epidermal growth factor receptor expression

Autor: E.J.J. van Zoelen, P.H.J. Peters, A.D.G. de Roos, Gijs B. Afink, W van Rotterdam, Alexander P.R. Theuvenet, S.T. van Genesen

Publikováno v: Scopus-Elsevier
Biochemical journal, 298 ( Pt 2), 335-340. Portland Press Ltd.
Biochemical Journal, 298, 335-340
Biochemical Journal, 298, 2, pp. 335-340

Normal rat kidney fibroblasts, grown to density arrest in the presence of epidermal growth factor (EGF), can be induced to undergo phenotypic transformation by treatment with transforming growth factor beta or retinoic acid. Here we show that bradyki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c7be9877ab7ce8b44a9e3e9b5091e8
https://doi.org/10.1042/bj2980335

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