Zobrazeno 1 - 10
of 51
pro vyhledávání: '"A.D. Shafton"'
Publikováno v:
Bioelectronics in Medicine. 1:21-27
Vagal nerve stimulation is widely used therapeutically but the fiber groups activated are often unknown. Aim: To establish a simple protocol to define stimulus thresholds for vagal A, B and C fibers. Methods: The intact left or right cervical vagus w
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Autor:
David B. Grayden, Robin M. McAllen, A.D. Shafton, John B. Furness, Catherine E. Davey, Martin J. Stebbing, Artemio Soto-Breceda
Publikováno v:
Journal of Neuroscience Methods. 338:108683
Background Peripheral autonomic nerves control visceral organs and convey information regarding their functional states and are, therefore, potential targets for new therapeutic and diagnostic approaches. Conventionally recorded multi-unit nerve acti
Autor:
John B. Furness, Robin M. McAllen, David B. Grayden, Artemio Soto-Breceda, Catherine E. Davey, A.D. Shafton, Martin J. Stebbing
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
A.D. Shafton, Tatiana Kameneva, John B. Furness, David Trevaks, Elma O'Sullivan-Greene, David B. Grayden, Sophie C. Payne, Robin M. McAllen
Publikováno v:
Journal of neural engineering. 15(5)
Objective. Artificial modulation of peripheral nerve signals (neuromodulation) by electrical stimulation is an innovation with potential to develop treatments that replace or supplement drugs. One function of the nervous system that can be exploited
Publikováno v:
Temperature: Multidisciplinary Biomedical Journal
The thermoregulatory reflex effects of warming and cooling in the abdomen were investigated in 4 urethane-anesthetized Sprague-Dawley rats. Animals were shaved and surrounded by a water-perfused silastic jacket. Skin temperature under the jacket was
Autor:
A.D. Shafton, Robin M. McAllen
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 304:R804-R809
The brain stem premotor pathways controlling most noncardiovascular sympathetic outflows are unknown. Here, we mapped the brain stem neurons that drive sweating, by microinjecting excitant amino acid (l-glutamate or d,l-homocysteate: 0.4–3 nmol) in
Publikováno v:
Acta Oto-Laryngologica. 131:1155-1159
Betahistine dihydrochloride, a drug used widely in the systemic treatment of balance disorders such as Ménière's disease, was found to improve eustachian tube function when applied topically in the nasopharynx of rats.The study tested the effect of
Publikováno v:
Neurourology and Urodynamics. 29:S24-S28
Aims Intrinsic sphincter deficiency (ISD) causes significant disability and impairment of quality of life despite a range of treatment options. We investigated a novel method to improve sphincter function that does not appear to have been previously
Autor:
John B. Furness, Jason Witherington, L Abberley, Yasutake Shimizu, S Butler, A.D. Shafton, J D Brown, A Muir, Gareth J. Sanger
Publikováno v:
Neurogastroenterology & Motility. 21:71-77
Agonists of ghrelin receptors that cross the blood-brain barrier, but not ghrelin itself, administered peripherally (intravenous or subcutaneous), cause defecation by acting on centres in the lumbo-sacral spinal cord. It is not established whether or