Výsledky vyhledávání - "A.C. Boschero"

Akademický článek

Reduced pancreatic β-cell mass is associated with decreased FoxO1 and Erk1/2 protein phosphorylation in low-protein malnourished rats

Autor: A. Rafacho, V.A.G. Giozzet, A.C. Boschero, J.L.F. Abrantes, T.M. Cestari, E.M. Carneiro, J.R. Bosqueiro

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 42, Iss 10, Pp 935-941 (2009)

A low-protein diet leads to functional and structural pancreatic islet alterations, including islet hypotrophy. Insulin-signaling pathways are involved in several adaptive responses by pancreatic islets. We determined the levels of some insulin-signa

Externí odkaz: https://doaj.org/article/eca4621b228c4cd5ba9ab23ff08b69df

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Akademický článek

Effects of systemic administration of ciliary neurotrophic factor on Bax and Bcl-2 proteins in the lumbar spinal cord of neonatal rats after sciatic nerve transection

Autor: A.C.S. Rezende, A.S. Vieira, F. Rogério, L.F. Rezende, A.C. Boschero, A. Negro, F. Langone

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 41, Iss 11, Pp 1024-1028 (2008)

Ciliary neurotrophic factor (CNTF) is a cytokine that plays a neuroprotective role in relation to axotomized motoneurons. We determined the effect of daily subcutaneous doses of CNTF (1.2 µg/g for 5 days; N = 13) or PBS (N = 13) on the levels of mRN

Externí odkaz: https://doaj.org/article/4a1c0a106e144fa3b21ebab6c0205b79

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Akademický článek

Correlation of serum leptin and insulin levels of pregnant protein-restricted rats with predictive obesity variables

Autor: G.S. Macêdo, C.L.P. Ferreira, A. Menegaz, V.C. Arantes, R.V. Veloso, E.M. Carneiro, A.C. Boschero, C.M.P. Oller do Nascimento, M.Q. Latorraca, M.H.G. Gomes-da-Silva

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 41, Iss 6, Pp 519-525 (2008)

During pregnancy and protein restriction, changes in serum insulin and leptin levels, food intake and several metabolic parameters normally result in enhanced adiposity. We evaluated serum leptin and insulin levels and their correlations with some pr

Externí odkaz: https://doaj.org/article/d2af73bfba804f49aaa2dc5e2dc4d8be

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Akademický článek

Cholesteryl ester transfer protein expression is down-regulated in hyperinsulinemic transgenic mice

Autor: J.A. Berti, A.C. Casquero, P.R. Patrício, E.J.B. Bighetti, E.M. Carneiro, A.C. Boschero, H.C.F. Oliveira

Publikováno v: Journal of Lipid Research, Vol 44, Iss 10, Pp 1870-1876 (2003)

Cholesteryl ester transfer protein (CETP) mediates cholesteryl ester (CE) and triglyceride redistribution among plasma lipoproteins. In this work, we investigated whether varying levels of insulin regulate the CETP expression in vivo. Insulin deficie

Externí odkaz: https://doaj.org/article/4d5f2263a8134e5387c538477ac6c608

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Akademický článek

Development of the insulin secretion mechanism in fetal and neonatal rat pancreatic B-cells: response to glucose, K+, theophylline, and carbamylcholine

Autor: A.C. Mendonça, E.M. Carneiro, J.R. Bosqueiro, S.C. Crepaldi-Alves, A.C. Boschero

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 31, Iss 6, p 841 (1998)

We studied the development of the insulin secretion mechanism in the pancreas of fetal (19- and 21-day-old), neonatal (3-day-old), and adult (90-day-old) rats in response to stimulation with 8.3 or 16.7 mM glucose, 30 mM K+, 5 mM theophylline (Theo)

Externí odkaz: https://doaj.org/article/0d5b5b191dcd46ea8ee8bf7c5e8adfb1

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Akademický článek

Synergistic effect of glucose and prolactin on GLUT2 expression in cultured neonatal rat islets

Autor: S.C. Crepaldi-Alves, E.M. Carneiro, J.R. Bosqueiro, A.C. Boschero

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 30, Iss 3, p 359 (1997)

We studied the synergistic effect of glucose and prolactin (PRL) on insulin secretion and GLUT2 expression in cultured neonatal rat islets. After 7 days in culture, basal insulin secretion (2.8 mM glucose) was similar in control and PRL-treated islet

Externí odkaz: https://doaj.org/article/bbca09c90b964ffbb5f43bd99e7956f1

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Akademický článek

Duodenal-jejunal bypass normalizes pancreatic islet proliferation rate and function but not hepatic steatosis in hypothalamic obese rats

Autor: K.R. Cantelli, G.M. Soares, R.A. Ribeiro, S.L. Balbo, C. Lubaczeuski, A.C. Boschero, A.C.F. Araújo, M.L. Bonfleur

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 50, Iss 5

Modifications in life-style and/or pharmacotherapies contribute to weight loss and ameliorate the metabolic profile of diet-induced obese humans and rodents. Since these strategies fail to treat hypothalamic obesity, we have assessed the possible mec

Externí odkaz: https://doaj.org/article/af48ad6627034a758a528d8d66a5b66e

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