Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS

Autor: Carme Pedro, Heinz Sill, Michael Lübbert, Mario Cazzola, A.A. van de Loosdrecht, Heinz Tuechler, Javier Grau, Hartmut Döhner, Michael Pfeilstöcker, Alan F. List, A.A.N. Giagounidis, Peter L. Greenberg, M.G. Della Porta, Francesc Cobo, F. Solé, Gail J. Roboz, Guillermo Sanz, Sabine Blum, M. Martinez-de-Sola, Barbara Hildebrandt, Ulrich Germing, Detlef Haase, Amy E. DeZern, Rainer Haas, David P. Steensma, Richard F. Schlenk, M. Nomdedeu, Dolors Costa, María Díez-Campelo, Mikkael A. Sekeres, Christina Ganster, Rami S. Komrokji, Itziar Oiartzabal, Benet Nomdedeu, Reinhard Stauder, Arturo Pereira, Jordi Esteve, Sigrid Machherndl-Spandl, Maria Teresa Voso, Xavier Calvo, Maria-Teresa Cedena, Tobias Schroeder, Uwe Platzbecker, G. Garcia-Manero, Peter Valent, M. López-Pavía, Brayan Merchan, Blanca Xicoy, Andrea Kuendgen, Claudia D. Baldus

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Leukemia
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Kuendgen, A, Nomdedeu, M, Tuechler, H, Garcia-Manero, G, Komrokji, R S, Sekeres, M A, Della Porta, M G, Cazzola, M, DeZern, A E, Roboz, G J, Steensma, D P, Van de Loosdrecht, A A, Schlenk, R F, Grau, J, Calvo, X, Blum, S, Pereira, A, Valent, P, Costa, D, Giagounidis, A, Xicoy, B, Döhner, H, Platzbecker, U, Pedro, C, Lübbert, M, Oiartzabal, I, Díez-Campelo, M, Cedena, M T, Machherndl-Spandl, S, López-Pavía, M, Baldus, C D, Martinez-de-Sola, M, Stauder, R, Merchan, B, List, A, Ganster, C, Schroeder, T, Voso, M T, Pfeilstöcker, M, Sill, H, Hildebrandt, B, Esteve, J, Nomdedeu, B, Cobo, F, Haas, R, Sole, F, Germing, U, Greenberg, P L, Haase, D & Sanz, G 2021, ' Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification—an approach to classification of patients with t-MDS ', Leukemia, vol. 35, no. 3, pp. 835-849 . https://doi.org/10.1038/s41375-020-0917-7
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Leukemia, 35(3), 835-849. Nature Publishing Group
Leukemia, vol. 35, no. 3, pp. 835-849

In the current World Health Organization (WHO)-classification, therapy-related myelodysplastic syndromes (t-MDS) are categorized together with therapy-related acute myeloid leukemia (AML) and t-myelodysplastic/myeloproliferative neoplasms into one su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8a5a0f2557ae57357d5b4d74c913c1
https://ddd.uab.cat/record/236625

Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials

Autor: Luca Malcovati, A.A. van de Loosdrecht, Mikkael A. Sekeres, Reinhard Stauder, U. Germing, Silke Gloaguen, A.A.N. Giagounidis, Eva Hellström-Lindberg, Valeria Santini, T. de Witte, Pierre Fenaux, David P. Steensma, Lionel Ades, David G. Bowen, Uwe Platzbecker, G. Garcia-Manero

Publikováno v: Blood, 133, 10, pp. 1020-1030
Blood, 133, 1020-1030
Platzbecker, U, Fenaux, P, Adès, L, Giagounidis, A, Santini, V, van de Loosdrecht, A A, Bowen, D, de Witte, T, Garcia-Manero, G, Hellström-Lindberg, E, Germing, U, Stauder, R, Malcovati, L, Sekeres, M A, Steensma, D P & Gloaguen, S 2019, ' Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials ', Blood, vol. 133, no. 10, pp. 1020-1030 . https://doi.org/10.1182/blood-2018-06-857102
Blood, 133(10), 1020-1030. American Society of Hematology

The heterogeneity of myelodysplastic syndromes (MDSs) has made evaluating patient response to treatment challenging. In 2006, the International Working Group (IWG) proposed a revision to previously published standardized response criteria (IWG 2000)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db603c970e85f8a9fd5f174f577fb40c
https://hdl.handle.net/2066/202124

Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5)

Autor: Gesine Bug, Arnold Ganser, U. Platzbecker, Esther Schuler, Michael Lübbert, Ulrike Bacher, Katharina Götze, Philippe Schafhausen, Friederike Braulke, D. Haase, Katayoon Shirneshan, Michael Wulfert, Norbert Gattermann, Anne Letsch, Florian Nolte, Richard F. Schlenk, Guntram Büsche, Ulrich Germing, Rainer Haas, A.A.N. Giagounidis

Publikováno v: Leukemia. 30:1580-1582

Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c0d73e7749204b277a49e6de4462a6e
https://doi.org/10.1038/leu.2015.340

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts

Autor: Christina Mecucci, Bon Ham Yip, Jacqueline Boultwood, Andrea Pellagatti, Martin Attwood, David J. Roberts, Peter Vandenberghe, Jaroslaw P. Maciejewski, Chaitanya Vuppusetty, A A Lamikanra, A.A.N. Giagounidis, J. S. Wainscoat, Ulrich Germing

Publikováno v: Leukemia. 27:1760-1763

Activation of the mTOR signaling pathway by L -leucine in 5q- syndrome and other RPS14-deficient erythroblasts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226c93e26383ae3ddf66559307228b51
https://doi.org/10.1038/leu.2013.20

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

Autor: Andrea Pellagatti, C Fernandez-Santamaria, Marta Fernandez-Mercado, Eva Hellström-Lindberg, M. García-Delgado, Janet Perry, A.A.N. Giagounidis, María José Larrayoz, J. S. Wainscoat, Jacqueline Boultwood, M.G. Della Porta, Martin Jädersten, Maria-Jose Calasanz, Mario Cazzola, Luca Malcovati, Sally Killick

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce191f48130058b790e53a5538c4c296
https://doi.org/10.1038/leu.2010.20