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pro vyhledávání: '"A.A. Kandutsch"'
Autor:
A.A. Kandutsch
Publikováno v:
Journal of Lipid Research, Vol 7, Iss 5, Pp 603-611 (1966)
Aerobic incubation of 7-dehydrocholesterol with mouse liver microsomes in the presence of a detergent, an iron salt, and NADH or NADPH resulted in the conversion of the sterol to more polar products. In the presence of Fe3+ or low levels of Fe2+ the
Externí odkaz:
https://doaj.org/article/a407137a98f44f3c92aa652be7774bc0
Autor:
A.A. Kandutsch, E.B. Thompson
Publikováno v:
Journal of Biological Chemistry. 255:10813-10821
The differential binding of cholesterol and 25-hydroxycholesterol to cytosolic proteins in various types of cells was investigated. 25-Hydroxycholesterol taken up by six different established cell culture lines and by mouse spleen cells in primary cu
Autor:
A.A. Kandutsch, M.J. James
Publikováno v:
Journal of Biological Chemistry. 255:8618-8622
Dolichol is an isoprenoid lipid involved in the assembly of many membrane-bound and secreted glycoproteins. Dolichol biosynthesis can be considered as a branch of the cholesterol biosynthetic pathway subsequent to the reaction catalyzed by beta-hydro
Publikováno v:
Experimental Cell Research. 109:253-262
The response of leukemic cells from AKR/J mice to phytohemagglutinin (PHA) was compared with that of normal lymphocytes. PHA stimulated first cholesterol synthesis and then DNA synthesis in both lymphocytes and leukemic cells. The neoplastic cells we
Autor:
R.M. Packie, A.A. Kandutsch
Publikováno v:
Archives of Biochemistry and Biophysics. 140:122-130
Studies were undertaken to determine whether the inhibitory effects upon hepatic sterol synthesis of cholesterol and a number of structurally and metabolically related steroids could be differentiated in terms of inhibitory potency when fed or inject
Autor:
A.A. Kandutsch
Publikováno v:
Journal of Biological Chemistry. 237:358-362
Autor:
A.A. Kandutsch
Publikováno v:
Archives of Biochemistry and Biophysics. 75:148-162
The effects of endocrine gland extirpation and of treatment with hormones and unsaturated lipides on the skin sterols of mice were investigated. Concentrations of Δ7-cholestenol, a sterol localized in sebaceous glands, were depressed by castration o
Publikováno v:
Biochemical and biophysical research communications. 163(1)
Prenylated amino acid fragments have been isolated from prenylated proteins of Chinese hamster ovary cells. Gel-exclusion chromatography indicates that these proteins are modified by two different prenyl groups. The prenyl-amino acid fragments are la
Autor:
A.A. Kandutsch
Publikováno v:
Steroids. 10(1)
Subcellular fractions of mouse liver were tested for the presence of 3β-hydroxysteroid dehydrogenases capable of catalyzing the oxidation or reduction of certain C 27 and C 30 steroids. Enzymes present in the microsomal fraction catalyzed the oxidat