Zobrazeno 1 - 10
of 830
pro vyhledávání: '"A.-chou Su"'
Autor:
Chun-Hua Hung, Shang-Yin Wu, Cheng-I Daniel Yao, Hsuan-Heng Yeh, Chien-Chung Lin, Chang-Yao Chu, Tzu-Yu Huang, Meng-Ru Shen, Chun-Hung Lin, Wu-Chou Su
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract The IL6-GP130-STAT3 pathway facilitates lung cancer progression and resistance to tyrosine kinase inhibitors. Although glycosylation alters the stability of GP130, its effect on the ligand IL6 remains unclear. We herein find that N-glycosyla
Externí odkaz:
https://doaj.org/article/3a5cd2f7ff2f4570954e24e9d5764b19
Erdafitinib in Asian patients with advanced solid tumors: an open-label, single-arm, phase IIa trial
Autor:
Joon Oh Park, Yin-Hsun Feng, Wu-Chou Su, Do-Youn Oh, Bhumsuk Keam, Lin Shen, Sang-We Kim, Xiufeng Liu, Huimin Liao, Min Qing, Chong Zhang, Jiaqi Qian, Xiaodan Tang, Peng Li, Spyros Triantos, Hussein Sweiti
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background FGFR genomic aberrations occur in approximately 5–10% of human cancers. Erdafitinib has previously demonstrated efficacy and safety in FGFR-altered advanced solid tumors, such as gliomas, thoracic, gastrointestinal, gynecologica
Externí odkaz:
https://doaj.org/article/46cf37a8f4c5475998d9519b116a314e
Autor:
Michael Boyer, Rina Hui, Damien Urban, Philip Clingan, Wu-Chou Su, Celine Devaux, Shirish Gadgeel, Marina Garassino, Lance Leopold, Jeannie Daniel, Mihaela C. Munteanu, Ayman Samkari, Yiwen Luo, Delvys Rodriguez Abreu
Publikováno v:
BMC Cancer, Vol 23, Iss S1, Pp 1-12 (2024)
Abstract Background The combination of the checkpoint inhibitor (CPI) pembrolizumab and platinum-based chemotherapy is effective frontline therapy for advanced non-small cell lung cancer (NSCLC) lacking targetable mutations. Indoleamine 2,3- dioxygen
Externí odkaz:
https://doaj.org/article/f859d06395444ff68173b8d586898c31
Autor:
You-En Yang, Meng-Hsuan Hu, Yen-Chen Zeng, Yau-Lin Tseng, Ying-Yuan Chen, Wu-Chou Su, Chih-Peng Chang, Yi-Ching Wang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract IL-33 is a danger signal that binds to its receptor ST2L to promote tumor progression. This study identifies the IL-33/ST2L positive-feedback loop and the trafficking of ST2L membrane presentation in macrophages that contribute to lung tumor
Externí odkaz:
https://doaj.org/article/5eb3ecf778c04b50bdc1a72f3fada202
Publikováno v:
International Journal of Infectious Diseases, Vol 146, Iss , Pp 107119- (2024)
The ascomycete filamentous fungus Neurospora intermedia is commonly used in the food industry and considered nonpathogenic to humans. This study characterizes four N. intermedia isolates recovered from three patients. The first patient had a mediasti
Externí odkaz:
https://doaj.org/article/a4dc25e20bf9496db9d6653f9e39c51e
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-20 (2024)
Abstract Background Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor expressed on the surface of T cells. High expression of PD-1 leads to T-cell dysfunction in the tumor microenvironment (TME). However, the mechanism of intrac
Externí odkaz:
https://doaj.org/article/f40fd3e99c6c4fc29da14694cc63407c
Autor:
Chien-Huei Huang, Yung-Hsin Tseng, Wen-Shan Tsai, Chien-Chou Su, Ching-Lan Cheng, Yea-Huei Kao Yang, Yu-Ching Chang, Yi-Hsuan Liu
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 2, Pp 373-383 (2024)
Abstract Introduction Limited studies have evaluated the association between Clostridium difficile infection (CDI) and the duration of proton pump inhibitor (PPI) or histamine H2-receptor blocker (H2RA) use and provided a cutoff duration for PPI or H
Externí odkaz:
https://doaj.org/article/277364ca038840b593c1396f211c8e8d
Autor:
Chiao-En Wu, Yi-Hua Liao, Cheng-Lin Wu, Ruoh-Fang Yen, Chia-Chi Lin, Muh-Hwa Yang, Chueh-Chuan Yen, Wu-Chou Su, Chia-Jui Yen, Yi-Fang Chang, Ming-Fang Wu, Youngsen Yang, Chen-Yuan Lin, Wen-Chi Yang, Hui-Ching Wang, Cheng-Yuan Li, Yin-Yu Ho, Yao-Yu Chang, Chieh-Shan Wu, Hsiu-Cheng Hsu, Kuang-Hua Chen, Yenlin Huang, Chih-Jung Chen, Pei-Ju Chuang, Yung-Chi Lai, Yu-Yi Huang, Neng-Chuan Tseng, Yi-Ting Huang, Chia-Yu Chu, John Wen-Cheng Chang
Publikováno v:
Journal of the Formosan Medical Association, Vol 123, Iss 1, Pp 7-15 (2024)
Melanoma is rare in Taiwan. Asian melanoma is distinct from Western melanoma because acral and mucosal melanoma accounts for the majority of melanoma cases, leading to distinct tumor behaviors and genetic profiling. With consideration of the clinical
Externí odkaz:
https://doaj.org/article/04854f0faec04d159246a6f4a85d5aa9
Autor:
Yi-Chia Su, Chih-Chien Wu, Yu-Hsun Chen, Chien-Chou Su, Yu-Ching Chang, Meng-Che Hsieh, Yea-Huei Kao Yang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Primary tumor resection and metastasectomy may be beneficial for many patients with metastatic colorectal cancer (mCRC). Objective: To assess the differences in postoperative survival outcomes between adjuvant therapy with chemotherapy al
Externí odkaz:
https://doaj.org/article/fb9db7dc2cff41d8af54cddd358bbbf5
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Aberrant overexpression or activation of EGFR drives the development of non-small cell lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by secondary EGFR mutations or c-MET amplification/activation remain
Externí odkaz:
https://doaj.org/article/aaf04d699c2f45f6a88e5341ad07b036