Zobrazeno 1 - 10
of 21
pro vyhledávání: '"A.-Mohsen M.E. Omar"'
Publikováno v:
Bioorganic Chemistry. 109:104752
New benzoxazole derivatives containing 1,3,4-oxadiazole, 1,2,4-triazole or triazolothiadiazine rings were synthesized and screened for their in vitro antiproliferative activities against MCF-7 and MDA-MB-231 breast cancer cell lines using MTT assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628d6ded844658cd97426ec4e64bfc0c
https://doi.org/10.1016/j.bioorg.2021.104752
https://doi.org/10.1016/j.bioorg.2021.104752
Autor:
A.-Mohsen M.E. Omar, Doaa A. E. Issa, May E. Amr, Mai S. El-Shoukrofy, Ibrahim M. El-Ashmawy, Omaima M. Aboulwafa
Publikováno v:
MedChemComm. 8:1440-1451
A series of new substituted 6-methoxybenzothiazoles was synthesized and evaluated for their anthelmintic activity. The synthesis of the desired compounds was achieved through the key intermediate 2-(2-aminobenzothiazol-6-yloxy)acetohydrazide6. Target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c346d2fd6f8e7ac0e243c5180f392cd
https://doi.org/10.1039/c7md00140a
https://doi.org/10.1039/c7md00140a
Publikováno v:
Bioorganic Chemistry. 96:103593
New 2-substituted benzoxazole derivatives were synthesized and screened for their in vitro anti-proliferative activities against MCF-7 and MDA-MB-231 cell lines. Compounds 4b, 4d and 11c eliciting the highest activity against MCF-7 cells were further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e2529c88f0add38412a56d284af64a
https://doi.org/10.1016/j.bioorg.2020.103593
https://doi.org/10.1016/j.bioorg.2020.103593
Autor:
A.-Mohsen M.E. Omar, K. A. Ismail, Mervat Z. El-Azzouni, Salwa T. El-Mansoury, Alaa A. El-Tombary, Omaima M. Aboulwafa
Publikováno v:
ChemInform. 30
Several quinazoline derivatives containing substituted thiosemicarbazido and S -methylisothiosemicarbazido groups at the 2-position and at both the 2- and 4-positions have been synthesized. Treatment of the S -methylthiosemicarbazides with morpholine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bea86e657eee10c8194581f29efbd3
https://doi.org/10.1002/chin.199947169
https://doi.org/10.1002/chin.199947169
Autor:
Mervat Z. El-Azzouni, K. A. Ismail, Omaima M. Aboulwafa, A.-Mohsen M.E. Omar, Alaa A. El-Tombary, Salwa T. El-Mansoury
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 54(7)
Several quinazoline derivatives containing substituted thiosemicarbazido and S -methylisothiosemicarbazido groups at the 2-position and at both the 2- and 4-positions have been synthesized. Treatment of the S -methylthiosemicarbazides with morpholine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abd0a50494bcbf4cb83df0b80fc67d6
https://pubmed.ncbi.nlm.nih.gov/10486917
https://pubmed.ncbi.nlm.nih.gov/10486917
Autor:
Jacques Bourdais, A.-Mohsen M.E. Omar
Publikováno v:
Journal of Heterocyclic Chemistry. 17:555-558
A series of 3-substituted aminoimidazo[1,5-a]pyridine derivatives have been synthesized by cyclodesulfurization of a variety of N′-substituted-N-(2-pyridylmethyl)thioureas with dicyclohexylcarbodiimide (DCCD). 1H Nmr spectral analysis of all synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::020064d734dc3748328fc792cd1c922f
https://doi.org/10.1002/jhet.5570170327
https://doi.org/10.1002/jhet.5570170327
Publikováno v:
Journal of Pharmaceutical Sciences. 71:983-986
A series of steroidal oxazoline derivatives, containing different chains attached to the heterocyclic ring, were synthesized and examined for in vitro effect on bovine pancreatic ribonuclease activity. The results indicated weak anabolic properties f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc89db739a4e395a4b4d29b427926f44
https://doi.org/10.1002/jps.2600710907
https://doi.org/10.1002/jps.2600710907
Publikováno v:
Journal of Heterocyclic Chemistry. 16:1435-1438
A simple method for the synthesis of a novel series of 2-substituted amino-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones (11–16) has been established through two routes. The first involving the cyelodesulfurization of the thiosemicarbazides (3–8) wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e3dd63450de364be964aaaa31509b06
https://doi.org/10.1002/jhet.5570160729
https://doi.org/10.1002/jhet.5570160729
Publikováno v:
Journal of Heterocyclic Chemistry. 23:1731-1735
A series of 3-(N-substituted thiocarbamoyl)hydrazino-1,2,4-triazino[5,6-b]indole derivatives 3–22 has been synthesized and evaluated for in vitro antimicrobial activity. Although some of the products displayed significant activity against Staphyloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::866c974b02e973a20daefb953010d0af
https://doi.org/10.1002/jhet.5570230626
https://doi.org/10.1002/jhet.5570230626
Publikováno v:
Journal of Heterocyclic Chemistry. 21:1419-1423
Several novel estradiol-17α-triazolines were synthesized and tested in vitro for anabolic-catabolic acitivity and binding affinity to steroid receptors. While no binding affinity to steroid receptors was detected, due to the presence of a bulky tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1a22490459d46a23532a89c4933bf86
https://doi.org/10.1002/jhet.5570210539
https://doi.org/10.1002/jhet.5570210539