Zobrazeno 1 - 10
of 37
pro vyhledávání: '"A.-M. Kissmeyer"'
Publikováno v:
Xenobiotica. 20:417-434
1. The absorption, distribution, metabolism and excretion of 2-[3'-(2"-quinolyl-methoxy)phenylamino]benzoic acid (QMPB), a novel leukotriene D4/E4 antagonist, were investigated in rat, dog, guinea pig and man. 2. The oral absorption of the potassium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fbacc1d116c89cd8063d915bb7800c
https://doi.org/10.3109/00498259009046858
https://doi.org/10.3109/00498259009046858
Molecular evaluation of vitamin D3 receptor agonists designed for topical treatment of skin diseases
Publikováno v:
The Journal of investigative dermatology. 116(5)
MC903 (calcipotriol) is a synthetic, low calcemic analog of the nuclear hormone 1alpha,25-dihydroxyvitamin D3 and used in the treatment of psoriasis. The beneficial effects of MC903 on psoriasis are based on gene regulatory events. The genomic action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8f6287a2e819230db6b2c91862e70e2
https://pubmed.ncbi.nlm.nih.gov/11348471
https://pubmed.ncbi.nlm.nih.gov/11348471
Autor:
A M Kissmeyer, J T Mortensen
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 30(8)
1. Seocalcitol (EB 1089), a vitamin D analogue with strong antiproliferative effects in vitro and in vivo, is presently under clinical evaluation for the systemic treatment of various solid tumours. 2. The aim was to investigate the pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8cc21bd2b4526ff20a5d3950ff6abc
https://pubmed.ncbi.nlm.nih.gov/11037113
https://pubmed.ncbi.nlm.nih.gov/11037113
Publikováno v:
British journal of pharmacology. 125(4)
1. 1alpha,25-dihydroxyvitamin3 (VD) is a nuclear hormone that has important cell regulatory functions but also a strong calcemic effect. EB1089 is a potent antiproliferative VD analogue, which has a modified side chain resulting in increased metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8eaf20a9c2c2300e5682e66c1036004
https://pubmed.ncbi.nlm.nih.gov/9831892
https://pubmed.ncbi.nlm.nih.gov/9831892
Autor:
Graham R. Williams, E. Binderup, Glenville Jones, M. J. Calverley, A.-M. Kissmeyer, F. J. Dilworth, J. L. Nielsen, Hugh L.J. Makin
Publikováno v:
Scopus-Elsevier
Vitamin D analogs are valuable drugs with established and potential uses in hyperproliferative disorders. Lexacalcitol (KH1060) is over 100 times more active than 1alpha,25-dihydroxyvitamin D3 [1alpha,25-(OH)2D3], as judged by in vitro antiproliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2087df31f9422f90c8f4bbf9ed1483
https://pubmed.ncbi.nlm.nih.gov/9389535
https://pubmed.ncbi.nlm.nih.gov/9389535
Publikováno v:
Tijdschrift voor diergeneeskunde. 121(6)
Two different studies are described. The first study deals with the elimination of residues of trimethoprim (TMP), sulfatroxazole (STX) and its main metabolite N4-acetyl-sulfatroxazole (N4-acetyl-STX) in pigs. Thirty -six pigs were treated with trime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0cbf45fe4647b3e1571e9136c33fe52
https://pubmed.ncbi.nlm.nih.gov/8629271
https://pubmed.ncbi.nlm.nih.gov/8629271
Autor:
L. Binderup, A.-M. Kissmeyer
Publikováno v:
Vitamin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de2a2ce5e6d5b63d2093ad2ca1427e61
https://doi.org/10.1515/9783110882513-063
https://doi.org/10.1515/9783110882513-063
Publikováno v:
Endocrine. 3(4)
Vitamin D(3), 25-hydroxyvitamin D(3) (25OHD(3)) and 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) bind to the vitamin D binding protein (DBP) in the serum. During the development of synthetic vitamin D analogues, it has been shown that the majorit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d9166aaa3229aa2a778c1f526a228a
https://pubmed.ncbi.nlm.nih.gov/21153172
https://pubmed.ncbi.nlm.nih.gov/21153172
Autor:
A M, Kissmeyer, L, Binderup
Publikováno v:
Biochemical pharmacology. 41(11)
Calcipotriol (MC 903) is a novel analogue of the physiologically active metabolite of vitamin D3, 1 alpha,25-dihydroxycholecalciferol [1,25(OH)2D3]. MC 903 and 1,25(OH)2D3 have similar effects on cell proliferation and cell differentiation in vitro u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::674f002b1ead3996edf400da4fd92946
https://pubmed.ncbi.nlm.nih.gov/2043150
https://pubmed.ncbi.nlm.nih.gov/2043150
Publikováno v:
Skin Pharmacology & Physiology; Jan2009, Vol. 22 Issue 3, p124-127, 4p